| Full name: family with sequence similarity 218 member A | Alias Symbol: FLJ31659 | ||
| Type: protein-coding gene | Cytoband: 4q32.3 | ||
| Entrez ID: 152756 | HGNC ID: HGNC:26466 | Ensembl Gene: ENSG00000250486 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM218A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM218A | 152756 | 1553710_at | -0.0599 | 0.8905 | |
| GSE26886 | FAM218A | 152756 | 1553711_a_at | 0.0439 | 0.7095 | |
| GSE45670 | FAM218A | 152756 | 1553711_a_at | -0.1012 | 0.3088 | |
| GSE53622 | FAM218A | 152756 | 2489 | -0.7714 | 0.0000 | |
| GSE53624 | FAM218A | 152756 | 2489 | -1.3575 | 0.0000 | |
| GSE63941 | FAM218A | 152756 | 1553711_a_at | 0.2370 | 0.3550 | |
| GSE77861 | FAM218A | 152756 | 1553711_a_at | -0.0049 | 0.9626 | |
| SRP133303 | FAM218A | 152756 | RNAseq | 0.1572 | 0.7545 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FAM218A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FAM218A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM218A | 152756 | 0 | 11 | 19 | |
| GSE20123 | FAM218A | 152756 | 0 | 11 | 19 | |
| GSE43470 | FAM218A | 152756 | 0 | 14 | 29 | |
| GSE46452 | FAM218A | 152756 | 1 | 36 | 22 | |
| GSE47630 | FAM218A | 152756 | 0 | 22 | 18 | |
| GSE54993 | FAM218A | 152756 | 10 | 0 | 60 | |
| GSE54994 | FAM218A | 152756 | 1 | 12 | 40 | |
| GSE60625 | FAM218A | 152756 | 0 | 0 | 11 | |
| GSE74703 | FAM218A | 152756 | 0 | 12 | 24 | |
| GSE74704 | FAM218A | 152756 | 0 | 5 | 15 | |
| TCGA | FAM218A | 152756 | 10 | 33 | 53 |
Total number of gains: 22; Total number of losses: 156; Total Number of normals: 310.
Somatic mutations of FAM218A:
Generating mutation plots.
Highly correlated genes for FAM218A:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM218A | ASIC5 | 0.728219 | 3 | 0 | 3 |
| FAM218A | CCDC50 | 0.678651 | 3 | 0 | 3 |
| FAM218A | MORN3 | 0.615695 | 3 | 0 | 3 |
| FAM218A | RRAGD | 0.61388 | 3 | 0 | 3 |
| FAM218A | ATRNL1 | 0.609847 | 3 | 0 | 3 |
| FAM218A | PLXNB1 | 0.603378 | 3 | 0 | 3 |
| FAM218A | MAPT | 0.601846 | 3 | 0 | 3 |
| FAM218A | GOLGA8N | 0.591096 | 4 | 0 | 3 |
| FAM218A | MYEF2 | 0.590261 | 6 | 0 | 4 |
| FAM218A | ARID5A | 0.590196 | 3 | 0 | 3 |
| FAM218A | CGNL1 | 0.571642 | 3 | 0 | 3 |
| FAM218A | SLC6A4 | 0.552331 | 3 | 0 | 3 |
| FAM218A | GJC1 | 0.547773 | 4 | 0 | 3 |
| FAM218A | UHRF2 | 0.546157 | 3 | 0 | 3 |
| FAM218A | LAMB4 | 0.5449 | 4 | 0 | 3 |
| FAM218A | ART3 | 0.536059 | 4 | 0 | 3 |
| FAM218A | ASTN1 | 0.522818 | 4 | 0 | 3 |
| FAM218A | ANKS1B | 0.518188 | 4 | 0 | 3 |
| FAM218A | COBL | 0.517618 | 4 | 0 | 3 |
| FAM218A | HTR3A | 0.51728 | 4 | 0 | 3 |
For details and further investigation, click here
