| Full name: FA complementation group F | Alias Symbol: FAF | ||
| Type: protein-coding gene | Cytoband: 11p14.3 | ||
| Entrez ID: 2188 | HGNC ID: HGNC:3587 | Ensembl Gene: ENSG00000183161 | OMIM ID: 613897 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
FANCF involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03460 | Fanconi anemia pathway |
Expression of FANCF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FANCF | 2188 | 218689_at | -0.1092 | 0.9457 | |
| GSE20347 | FANCF | 2188 | 218689_at | -0.3533 | 0.0206 | |
| GSE23400 | FANCF | 2188 | 218689_at | 0.1391 | 0.0013 | |
| GSE26886 | FANCF | 2188 | 218689_at | 0.0288 | 0.9621 | |
| GSE29001 | FANCF | 2188 | 218689_at | 0.1216 | 0.7253 | |
| GSE38129 | FANCF | 2188 | 218689_at | -0.0205 | 0.9131 | |
| GSE45670 | FANCF | 2188 | 218689_at | 0.0645 | 0.8367 | |
| GSE53622 | FANCF | 2188 | 12924 | 0.4039 | 0.0000 | |
| GSE53624 | FANCF | 2188 | 69574 | 0.1707 | 0.0363 | |
| GSE63941 | FANCF | 2188 | 218689_at | 0.3714 | 0.6500 | |
| GSE77861 | FANCF | 2188 | 218689_at | -0.1167 | 0.7332 | |
| GSE97050 | FANCF | 2188 | A_33_P3386364 | 0.7444 | 0.1316 | |
| SRP007169 | FANCF | 2188 | RNAseq | -0.5323 | 0.2895 | |
| SRP008496 | FANCF | 2188 | RNAseq | 0.0601 | 0.8601 | |
| SRP064894 | FANCF | 2188 | RNAseq | 0.0915 | 0.6922 | |
| SRP133303 | FANCF | 2188 | RNAseq | 0.3855 | 0.0636 | |
| SRP159526 | FANCF | 2188 | RNAseq | -0.1952 | 0.4218 | |
| SRP193095 | FANCF | 2188 | RNAseq | -0.2448 | 0.1363 | |
| SRP219564 | FANCF | 2188 | RNAseq | 0.6918 | 0.1074 | |
| TCGA | FANCF | 2188 | RNAseq | -0.0402 | 0.6671 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FANCF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FANCF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FANCF | 2188 | 0 | 11 | 19 | |
| GSE20123 | FANCF | 2188 | 0 | 11 | 19 | |
| GSE43470 | FANCF | 2188 | 1 | 6 | 36 | |
| GSE46452 | FANCF | 2188 | 7 | 5 | 47 | |
| GSE47630 | FANCF | 2188 | 3 | 10 | 27 | |
| GSE54993 | FANCF | 2188 | 3 | 0 | 67 | |
| GSE54994 | FANCF | 2188 | 3 | 12 | 38 | |
| GSE60625 | FANCF | 2188 | 0 | 0 | 11 | |
| GSE74703 | FANCF | 2188 | 1 | 4 | 31 | |
| GSE74704 | FANCF | 2188 | 0 | 9 | 11 | |
| TCGA | FANCF | 2188 | 12 | 24 | 60 |
Total number of gains: 30; Total number of losses: 92; Total Number of normals: 366.
Somatic mutations of FANCF:
Generating mutation plots.
Highly correlated genes for FANCF:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FANCF | ICA1 | 0.702907 | 3 | 0 | 3 |
| FANCF | MX2 | 0.632777 | 3 | 0 | 3 |
| FANCF | KRT19 | 0.632576 | 4 | 0 | 3 |
| FANCF | PRSS16 | 0.608892 | 3 | 0 | 3 |
| FANCF | METTL18 | 0.597557 | 6 | 0 | 5 |
| FANCF | ARFGEF1 | 0.583576 | 3 | 0 | 3 |
| FANCF | TRIM14 | 0.579511 | 6 | 0 | 3 |
| FANCF | SCFD2 | 0.56959 | 3 | 0 | 3 |
| FANCF | TUSC1 | 0.56563 | 6 | 0 | 3 |
| FANCF | USP30 | 0.560424 | 4 | 0 | 3 |
| FANCF | PCLO | 0.558597 | 6 | 0 | 4 |
| FANCF | RPL6 | 0.554445 | 4 | 0 | 3 |
| FANCF | MFSD1 | 0.553688 | 4 | 0 | 3 |
| FANCF | KLHL12 | 0.535503 | 5 | 0 | 3 |
| FANCF | GATA3 | 0.530821 | 4 | 0 | 3 |
| FANCF | ARL14EP | 0.514336 | 5 | 0 | 3 |
| FANCF | SETDB2 | 0.501993 | 4 | 0 | 3 |
| FANCF | ANKEF1 | 0.500508 | 7 | 0 | 3 |
| FANCF | PHF10 | 0.50026 | 5 | 0 | 3 |
For details and further investigation, click here
