| Full name: keratin 19 | Alias Symbol: K19|CK19|K1CS|MGC15366 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3880 | HGNC ID: HGNC:6436 | Ensembl Gene: ENSG00000171345 | OMIM ID: 148020 |
| Related drugs: CHEMBL35482, DEXAMETHASONE... [more] | |||
Expression of KRT19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT19 | 3880 | 201650_at | -0.4345 | 0.8160 | |
| GSE20347 | KRT19 | 3880 | 201650_at | -0.6944 | 0.3175 | |
| GSE23400 | KRT19 | 3880 | 201650_at | -0.8558 | 0.0409 | |
| GSE26886 | KRT19 | 3880 | 201650_at | -0.4343 | 0.3972 | |
| GSE29001 | KRT19 | 3880 | 201650_at | -2.1723 | 0.0751 | |
| GSE38129 | KRT19 | 3880 | 201650_at | -0.0479 | 0.9580 | |
| GSE45670 | KRT19 | 3880 | 201650_at | -0.1705 | 0.7911 | |
| GSE53622 | KRT19 | 3880 | 33039 | -0.9344 | 0.0006 | |
| GSE53624 | KRT19 | 3880 | 33039 | -1.1204 | 0.0000 | |
| GSE63941 | KRT19 | 3880 | 201650_at | 5.7923 | 0.0469 | |
| GSE77861 | KRT19 | 3880 | 201650_at | -0.2734 | 0.7645 | |
| GSE97050 | KRT19 | 3880 | A_23_P66798 | 0.7348 | 0.5553 | |
| SRP007169 | KRT19 | 3880 | RNAseq | -1.4983 | 0.0125 | |
| SRP008496 | KRT19 | 3880 | RNAseq | -1.0731 | 0.0267 | |
| SRP064894 | KRT19 | 3880 | RNAseq | -1.0445 | 0.0543 | |
| SRP133303 | KRT19 | 3880 | RNAseq | 0.2494 | 0.5790 | |
| SRP159526 | KRT19 | 3880 | RNAseq | -0.0149 | 0.9851 | |
| SRP193095 | KRT19 | 3880 | RNAseq | -0.7549 | 0.0318 | |
| SRP219564 | KRT19 | 3880 | RNAseq | -0.6091 | 0.6082 | |
| TCGA | KRT19 | 3880 | RNAseq | 0.0370 | 0.8898 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by KRT19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT19 | 3880 | 6 | 2 | 22 | |
| GSE20123 | KRT19 | 3880 | 6 | 2 | 22 | |
| GSE43470 | KRT19 | 3880 | 1 | 2 | 40 | |
| GSE46452 | KRT19 | 3880 | 34 | 0 | 25 | |
| GSE47630 | KRT19 | 3880 | 8 | 1 | 31 | |
| GSE54993 | KRT19 | 3880 | 3 | 4 | 63 | |
| GSE54994 | KRT19 | 3880 | 8 | 5 | 40 | |
| GSE60625 | KRT19 | 3880 | 4 | 0 | 7 | |
| GSE74703 | KRT19 | 3880 | 1 | 1 | 34 | |
| GSE74704 | KRT19 | 3880 | 4 | 1 | 15 | |
| TCGA | KRT19 | 3880 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT19:
Generating mutation plots.
Highly correlated genes for KRT19:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT19 | TXNL4A | 0.66399 | 3 | 0 | 3 |
| KRT19 | CAMSAP3 | 0.650455 | 7 | 0 | 5 |
| KRT19 | UPK3B | 0.650161 | 3 | 0 | 3 |
| KRT19 | ZKSCAN1 | 0.636838 | 3 | 0 | 3 |
| KRT19 | C6orf132 | 0.63511 | 4 | 0 | 4 |
| KRT19 | S100A11 | 0.633976 | 4 | 0 | 3 |
| KRT19 | FANCF | 0.632576 | 4 | 0 | 3 |
| KRT19 | PLEKHN1 | 0.628499 | 3 | 0 | 3 |
| KRT19 | LAD1 | 0.627447 | 5 | 0 | 4 |
| KRT19 | SPINT2 | 0.625359 | 4 | 0 | 4 |
| KRT19 | TSEN54 | 0.62284 | 5 | 0 | 4 |
| KRT19 | CLDN7 | 0.621695 | 11 | 0 | 9 |
| KRT19 | CRB3 | 0.617201 | 5 | 0 | 4 |
| KRT19 | SETMAR | 0.612873 | 3 | 0 | 3 |
| KRT19 | PKP3 | 0.609519 | 5 | 0 | 5 |
| KRT19 | TPRN | 0.60686 | 5 | 0 | 4 |
| KRT19 | LIPH | 0.601566 | 7 | 0 | 5 |
| KRT19 | NCCRP1 | 0.600199 | 3 | 0 | 3 |
| KRT19 | BAIAP2 | 0.600099 | 4 | 0 | 3 |
| KRT19 | ELF3 | 0.598866 | 13 | 0 | 10 |
For details and further investigation, click here
