| Full name: beta-1,3-galactosyltransferase 5 | Alias Symbol: beta3Gal-T5|B3GalT-V|GLCT5|B3T5 | ||
| Type: protein-coding gene | Cytoband: 21q22.2 | ||
| Entrez ID: 10317 | HGNC ID: HGNC:920 | Ensembl Gene: ENSG00000183778 | OMIM ID: 604066 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of B3GALT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GALT5 | 10317 | 230269_at | -0.0727 | 0.9283 | |
| GSE20347 | B3GALT5 | 10317 | 206947_at | -0.1197 | 0.1114 | |
| GSE23400 | B3GALT5 | 10317 | 206947_at | -0.1956 | 0.0000 | |
| GSE26886 | B3GALT5 | 10317 | 230269_at | -0.0147 | 0.9820 | |
| GSE29001 | B3GALT5 | 10317 | 206947_at | -0.3432 | 0.0286 | |
| GSE38129 | B3GALT5 | 10317 | 206947_at | -0.1814 | 0.0075 | |
| GSE45670 | B3GALT5 | 10317 | 230269_at | 0.1807 | 0.6413 | |
| GSE53622 | B3GALT5 | 10317 | 99379 | -1.9869 | 0.0000 | |
| GSE53624 | B3GALT5 | 10317 | 99379 | -2.0639 | 0.0000 | |
| GSE63941 | B3GALT5 | 10317 | 230269_at | -0.0142 | 0.9624 | |
| GSE77861 | B3GALT5 | 10317 | 230269_at | 0.0699 | 0.8868 | |
| GSE97050 | B3GALT5 | 10317 | A_23_P102919 | -0.2076 | 0.6050 | |
| SRP007169 | B3GALT5 | 10317 | RNAseq | -0.4454 | 0.5519 | |
| SRP064894 | B3GALT5 | 10317 | RNAseq | -0.5472 | 0.3514 | |
| SRP133303 | B3GALT5 | 10317 | RNAseq | -0.7313 | 0.2166 | |
| SRP159526 | B3GALT5 | 10317 | RNAseq | -0.4042 | 0.6654 | |
| SRP193095 | B3GALT5 | 10317 | RNAseq | -1.9395 | 0.0002 | |
| SRP219564 | B3GALT5 | 10317 | RNAseq | -0.5124 | 0.5706 | |
| TCGA | B3GALT5 | 10317 | RNAseq | -1.5912 | 0.0079 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by B3GALT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GALT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GALT5 | 10317 | 2 | 11 | 17 | |
| GSE20123 | B3GALT5 | 10317 | 2 | 11 | 17 | |
| GSE43470 | B3GALT5 | 10317 | 0 | 10 | 33 | |
| GSE46452 | B3GALT5 | 10317 | 1 | 21 | 37 | |
| GSE47630 | B3GALT5 | 10317 | 6 | 17 | 17 | |
| GSE54993 | B3GALT5 | 10317 | 8 | 1 | 61 | |
| GSE54994 | B3GALT5 | 10317 | 3 | 8 | 42 | |
| GSE60625 | B3GALT5 | 10317 | 0 | 0 | 11 | |
| GSE74703 | B3GALT5 | 10317 | 0 | 8 | 28 | |
| GSE74704 | B3GALT5 | 10317 | 1 | 7 | 12 | |
| TCGA | B3GALT5 | 10317 | 8 | 42 | 46 |
Total number of gains: 31; Total number of losses: 136; Total Number of normals: 321.
Somatic mutations of B3GALT5:
Generating mutation plots.
Highly correlated genes for B3GALT5:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GALT5 | CHST9 | 0.663045 | 4 | 0 | 4 |
| B3GALT5 | CYP2C19 | 0.64696 | 5 | 0 | 5 |
| B3GALT5 | MYCN | 0.6391 | 3 | 0 | 3 |
| B3GALT5 | FBXO4 | 0.637799 | 3 | 0 | 3 |
| B3GALT5 | AKAP7 | 0.635816 | 3 | 0 | 3 |
| B3GALT5 | HMGCS1 | 0.632319 | 3 | 0 | 3 |
| B3GALT5 | ABHD3 | 0.625429 | 3 | 0 | 3 |
| B3GALT5 | ZNF419 | 0.624783 | 3 | 0 | 3 |
| B3GALT5 | SYT13 | 0.624053 | 4 | 0 | 3 |
| B3GALT5 | LRRD1 | 0.622606 | 3 | 0 | 3 |
| B3GALT5 | ST6GALNAC1 | 0.620082 | 4 | 0 | 3 |
| B3GALT5 | MGAT3 | 0.618935 | 3 | 0 | 3 |
| B3GALT5 | E2F2 | 0.613911 | 4 | 0 | 4 |
| B3GALT5 | TOX3 | 0.613078 | 5 | 0 | 4 |
| B3GALT5 | MTHFR | 0.60749 | 4 | 0 | 4 |
| B3GALT5 | USP54 | 0.605302 | 4 | 0 | 3 |
| B3GALT5 | SERPINB11 | 0.603933 | 4 | 0 | 3 |
| B3GALT5 | B3GNT6 | 0.602787 | 3 | 0 | 3 |
| B3GALT5 | ATP6V0E2 | 0.599938 | 3 | 0 | 3 |
| B3GALT5 | ZFPL1 | 0.593799 | 3 | 0 | 3 |
For details and further investigation, click here
