ZNF658

 

Full name: zinc finger protein 658 Alias Symbol: MGC35232|DKFZp572C163|FLJ32813
Type: protein-coding gene Cytoband: 9q21.11
Entrez ID: 26149 HGNC ID: HGNC:25226 Ensembl Gene: ENSG00000274349 OMIM ID: 616290
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZNF658:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF658 26149 231950_at -0.4803 0.6021
GSE26886 ZNF658 26149 231950_at 0.0210 0.9604
GSE45670 ZNF658 26149 231950_at -0.2712 0.4036
GSE53622 ZNF658 26149 6658 -0.7071 0.0000
GSE53624 ZNF658 26149 51934 -0.6363 0.0000
GSE63941 ZNF658 26149 231950_at -0.3214 0.6842
GSE77861 ZNF658 26149 231950_at -0.4111 0.0044
GSE97050 ZNF658 26149 A_23_P419202 -0.4649 0.1556
SRP007169 ZNF658 26149 RNAseq -0.5588 0.3861
SRP008496 ZNF658 26149 RNAseq 0.0969 0.8151
SRP064894 ZNF658 26149 RNAseq -0.3244 0.1683
SRP133303 ZNF658 26149 RNAseq -0.8406 0.0009
SRP159526 ZNF658 26149 RNAseq -0.7562 0.0500
SRP193095 ZNF658 26149 RNAseq -0.6202 0.0014
SRP219564 ZNF658 26149 RNAseq -0.4465 0.3633
TCGA ZNF658 26149 RNAseq -0.0964 0.4466

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF658 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF658:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF658 26149 4 13 13
GSE20123 ZNF658 26149 4 13 13
GSE43470 ZNF658 26149 1 8 34
GSE46452 ZNF658 26149 6 16 37
GSE47630 ZNF658 26149 1 20 19
GSE54993 ZNF658 26149 6 0 64
GSE54994 ZNF658 26149 4 15 34
GSE60625 ZNF658 26149 0 0 11
GSE74703 ZNF658 26149 1 6 29
GSE74704 ZNF658 26149 1 10 9
TCGA ZNF658 26149 22 42 32

Total number of gains: 50; Total number of losses: 143; Total Number of normals: 295.  


 

Somatic mutations of ZNF658:

 

Generating mutation plots.

 

Highly correlated genes for ZNF658:

 

Showing top 20/150 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF658FBXO40.662062303
ZNF658NFKBIL10.63842303
ZNF658PLEKHF20.629738404
ZNF658GOLPH3L0.627823403
ZNF658ZNF1400.625468303
ZNF658UBA50.623112403
ZNF658BLOC1S10.609821403
ZNF658FBXW20.605594303
ZNF658UXT0.603677303
ZNF658MST10.602843303
ZNF658ZNF450.60256403
ZNF658ANKRD490.599695504
ZNF658SLC44A30.597858403
ZNF658DEPTOR0.597346303
ZNF658ZNF4430.591724504
ZNF658FBXO100.591297403
ZNF658USP460.59124403
ZNF658CHPT10.590802504
ZNF658USP300.588733303
ZNF658SCAF110.588146303

For details and further investigation, click here