| Full name: V-set pre-B cell surrogate light chain 3 | Alias Symbol: 8HS20 | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 29802 | HGNC ID: HGNC:12710 | Ensembl Gene: ENSG00000128218 | OMIM ID: 605017 |
| Drug and gene relationship at DGIdb | |||
Expression of VPREB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPREB3 | 29802 | 220068_at | 0.1235 | 0.9053 | |
| GSE20347 | VPREB3 | 29802 | 220068_at | 0.1298 | 0.3315 | |
| GSE23400 | VPREB3 | 29802 | 220068_at | -0.0408 | 0.4136 | |
| GSE26886 | VPREB3 | 29802 | 220068_at | 0.0167 | 0.9337 | |
| GSE29001 | VPREB3 | 29802 | 220068_at | -0.0299 | 0.8815 | |
| GSE38129 | VPREB3 | 29802 | 220068_at | -0.0041 | 0.9883 | |
| GSE45670 | VPREB3 | 29802 | 220068_at | 0.1849 | 0.4860 | |
| GSE53622 | VPREB3 | 29802 | 57919 | 0.1580 | 0.1094 | |
| GSE53624 | VPREB3 | 29802 | 57919 | -0.1879 | 0.1071 | |
| GSE63941 | VPREB3 | 29802 | 220068_at | 0.5022 | 0.2104 | |
| GSE77861 | VPREB3 | 29802 | 220068_at | 0.0643 | 0.7556 | |
| GSE97050 | VPREB3 | 29802 | A_33_P3401990 | 0.3397 | 0.2883 | |
| TCGA | VPREB3 | 29802 | RNAseq | -0.1189 | 0.7976 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPREB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPREB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPREB3 | 29802 | 5 | 7 | 18 | |
| GSE20123 | VPREB3 | 29802 | 5 | 6 | 19 | |
| GSE43470 | VPREB3 | 29802 | 3 | 6 | 34 | |
| GSE46452 | VPREB3 | 29802 | 32 | 1 | 26 | |
| GSE47630 | VPREB3 | 29802 | 8 | 5 | 27 | |
| GSE54993 | VPREB3 | 29802 | 3 | 6 | 61 | |
| GSE54994 | VPREB3 | 29802 | 11 | 7 | 35 | |
| GSE60625 | VPREB3 | 29802 | 5 | 0 | 6 | |
| GSE74703 | VPREB3 | 29802 | 3 | 5 | 28 | |
| GSE74704 | VPREB3 | 29802 | 2 | 3 | 15 | |
| TCGA | VPREB3 | 29802 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of VPREB3:
Generating mutation plots.
Highly correlated genes for VPREB3:
Showing top 20/210 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPREB3 | FCRL1 | 0.780662 | 3 | 0 | 3 |
| VPREB3 | CR2 | 0.734439 | 9 | 0 | 9 |
| VPREB3 | KIR2DL5A | 0.726437 | 4 | 0 | 4 |
| VPREB3 | TBC1D10C | 0.712252 | 4 | 0 | 3 |
| VPREB3 | MS4A1 | 0.70197 | 8 | 0 | 7 |
| VPREB3 | CD79B | 0.689142 | 7 | 0 | 6 |
| VPREB3 | PTPRCAP | 0.676545 | 8 | 0 | 7 |
| VPREB3 | ALPL | 0.674255 | 4 | 0 | 4 |
| VPREB3 | IKZF3 | 0.671141 | 5 | 0 | 4 |
| VPREB3 | SLC9A5 | 0.668613 | 3 | 0 | 3 |
| VPREB3 | TCL1A | 0.666411 | 7 | 0 | 6 |
| VPREB3 | FCAMR | 0.659312 | 5 | 0 | 4 |
| VPREB3 | NCR3 | 0.65556 | 5 | 0 | 5 |
| VPREB3 | DDC | 0.652627 | 3 | 0 | 3 |
| VPREB3 | WAS | 0.647768 | 6 | 0 | 4 |
| VPREB3 | TSPO2 | 0.646055 | 4 | 0 | 3 |
| VPREB3 | CD19 | 0.645476 | 10 | 0 | 8 |
| VPREB3 | KLK2 | 0.644874 | 3 | 0 | 3 |
| VPREB3 | CCDC177 | 0.642272 | 4 | 0 | 3 |
| VPREB3 | PRODH2 | 0.640005 | 4 | 0 | 4 |
For details and further investigation, click here
