FGF9

 

Full name: fibroblast growth factor 9 Alias Symbol: 
Type: protein-coding gene Cytoband: 13q12.11
Entrez ID: 2254 HGNC ID: HGNC:3687 Ensembl Gene: ENSG00000102678 OMIM ID: 600921
Drug and gene relationship at DGIdb

 

FGF9 involved pathways:

KEGG pathway Description View
hsa04010MAPK signaling pathway
hsa04014Ras signaling pathway
hsa04015Rap1 signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa05200Pathways in cancer
hsa05218Melanoma

 

Expression of FGF9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FGF9 2254 206404_at -0.3583 0.5691
GSE20347 FGF9 2254 206404_at 0.1746 0.3569
GSE23400 FGF9 2254 206404_at -0.1519 0.0731
GSE26886 FGF9 2254 206404_at 0.0287 0.8934
GSE29001 FGF9 2254 206404_at 0.1739 0.6469
GSE38129 FGF9 2254 206404_at -0.1435 0.5409
GSE45670 FGF9 2254 206404_at -0.6733 0.0114
GSE53622 FGF9 2254 100411 -2.1880 0.0000
GSE53624 FGF9 2254 74468 -0.1464 0.2734
GSE63941 FGF9 2254 206404_at -1.3569 0.0500
GSE77861 FGF9 2254 206404_at 0.0412 0.7810
SRP133303 FGF9 2254 RNAseq 0.2873 0.4137
TCGA FGF9 2254 RNAseq -1.2854 0.0232

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by FGF9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FGF9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FGF9 2254 1 14 15
GSE20123 FGF9 2254 1 13 16
GSE43470 FGF9 2254 2 13 28
GSE46452 FGF9 2254 0 33 26
GSE47630 FGF9 2254 3 26 11
GSE54993 FGF9 2254 11 2 57
GSE54994 FGF9 2254 1 13 39
GSE60625 FGF9 2254 0 3 8
GSE74703 FGF9 2254 2 10 24
GSE74704 FGF9 2254 0 11 9
TCGA FGF9 2254 6 43 47

Total number of gains: 27; Total number of losses: 181; Total Number of normals: 280.  


 

Somatic mutations of FGF9:

 

Generating mutation plots.

 

Highly correlated genes for FGF9:

 

Showing top 20/163 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FGF9OMD0.703544303
FGF9ADAMTS190.671832303
FGF9ERVFRD-10.663658403
FGF9TMEM255A0.656414403
FGF9MAP60.639515303
FGF9CYS10.635528403
FGF9ITSN10.628925404
FGF9FGL10.62546303
FGF9CCDC800.614642303
FGF9OLFML10.613128403
FGF9ECM20.610559403
FGF9PNMA20.607905504
FGF9BBS10.607454403
FGF9MAP1A0.601291706
FGF9KIF5C0.599394604
FGF9FXYD10.598939403
FGF9VIT0.594075303
FGF9PDGFD0.592901504
FGF9NACAD0.592547604
FGF9ASTN10.591291604

For details and further investigation, click here