| Full name: endogenous retrovirus group FRD member 1, envelope | Alias Symbol: HERV-W/FRD|HERV-FRD|envFRD|ERVFRDE1|syncytin-2 | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 405754 | HGNC ID: HGNC:33823 | Ensembl Gene: ENSG00000244476 | OMIM ID: 610524 |
Expression of ERVFRD-1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERVFRD-1 | 405754 | 1555880_at | -0.2507 | 0.3397 | |
| GSE26886 | ERVFRD-1 | 405754 | 1555880_at | 0.0457 | 0.7546 | |
| GSE45670 | ERVFRD-1 | 405754 | 1555880_at | -0.2594 | 0.0340 | |
| GSE53622 | ERVFRD-1 | 405754 | 90207 | -0.2625 | 0.0056 | |
| GSE53624 | ERVFRD-1 | 405754 | 90207 | -0.1677 | 0.0070 | |
| GSE63941 | ERVFRD-1 | 405754 | 1555880_at | -0.0115 | 0.9545 | |
| GSE77861 | ERVFRD-1 | 405754 | 1555880_at | 0.0509 | 0.7005 | |
| GSE97050 | ERVFRD-1 | 405754 | A_24_P924261 | -0.0643 | 0.8545 | |
| SRP133303 | ERVFRD-1 | 405754 | RNAseq | 0.1997 | 0.2221 | |
| SRP159526 | ERVFRD-1 | 405754 | RNAseq | -0.0986 | 0.8386 | |
| SRP193095 | ERVFRD-1 | 405754 | RNAseq | 0.2949 | 0.1124 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ERVFRD-1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ERVFRD-1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERVFRD-1 | 405754 | 4 | 7 | 19 | |
| GSE20123 | ERVFRD-1 | 405754 | 4 | 7 | 19 | |
| GSE43470 | ERVFRD-1 | 405754 | 9 | 2 | 32 | |
| GSE46452 | ERVFRD-1 | 405754 | 1 | 10 | 48 | |
| GSE47630 | ERVFRD-1 | 405754 | 7 | 8 | 25 | |
| GSE54993 | ERVFRD-1 | 405754 | 1 | 1 | 68 | |
| GSE54994 | ERVFRD-1 | 405754 | 10 | 3 | 40 | |
| GSE60625 | ERVFRD-1 | 405754 | 0 | 1 | 10 | |
| GSE74703 | ERVFRD-1 | 405754 | 8 | 2 | 26 | |
| GSE74704 | ERVFRD-1 | 405754 | 2 | 3 | 15 |
Total number of gains: 46; Total number of losses: 44; Total Number of normals: 302.
Somatic mutations of ERVFRD-1:
Generating mutation plots.
Highly correlated genes for ERVFRD-1:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERVFRD-1 | SPTBN1 | 0.736451 | 3 | 0 | 3 |
| ERVFRD-1 | ZBTB26 | 0.735206 | 3 | 0 | 3 |
| ERVFRD-1 | SLIT3 | 0.733646 | 4 | 0 | 4 |
| ERVFRD-1 | FGF7 | 0.728847 | 3 | 0 | 3 |
| ERVFRD-1 | AGTR1 | 0.722087 | 3 | 0 | 3 |
| ERVFRD-1 | CASC4 | 0.710809 | 3 | 0 | 3 |
| ERVFRD-1 | S1PR1 | 0.703609 | 3 | 0 | 3 |
| ERVFRD-1 | NPY1R | 0.702684 | 4 | 0 | 4 |
| ERVFRD-1 | PPFIBP1 | 0.699072 | 3 | 0 | 3 |
| ERVFRD-1 | ACO1 | 0.694554 | 3 | 0 | 3 |
| ERVFRD-1 | CAPN7 | 0.690888 | 3 | 0 | 3 |
| ERVFRD-1 | INMT | 0.689971 | 3 | 0 | 3 |
| ERVFRD-1 | PEAK1 | 0.686397 | 3 | 0 | 3 |
| ERVFRD-1 | FAM13A | 0.684976 | 3 | 0 | 3 |
| ERVFRD-1 | DPYSL2 | 0.683115 | 3 | 0 | 3 |
| ERVFRD-1 | FHL5 | 0.676065 | 3 | 0 | 3 |
| ERVFRD-1 | ZNF25 | 0.67498 | 3 | 0 | 3 |
| ERVFRD-1 | ADAMTS5 | 0.674767 | 3 | 0 | 3 |
| ERVFRD-1 | TIMP4 | 0.674391 | 3 | 0 | 3 |
| ERVFRD-1 | FRY | 0.670029 | 3 | 0 | 3 |
For details and further investigation, click here
