CCDC85B

 

Full name: coiled-coil domain containing 85B Alias Symbol: DIPA
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 11007 HGNC ID: HGNC:24926 Ensembl Gene: ENSG00000175602 OMIM ID: 605360
Drug and gene relationship at DGIdb

 

Expression of CCDC85B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC85B 11007 204610_s_at 0.3621 0.4047
GSE20347 CCDC85B 11007 204610_s_at 0.5652 0.0122
GSE23400 CCDC85B 11007 204610_s_at 0.2936 0.0091
GSE26886 CCDC85B 11007 204610_s_at 1.2468 0.0001
GSE29001 CCDC85B 11007 204610_s_at 0.3218 0.4479
GSE38129 CCDC85B 11007 204610_s_at 0.2322 0.2132
GSE45670 CCDC85B 11007 204610_s_at 0.0512 0.8249
GSE53622 CCDC85B 11007 992 0.2959 0.0000
GSE53624 CCDC85B 11007 992 0.4050 0.0000
GSE63941 CCDC85B 11007 204610_s_at -0.4911 0.4163
GSE77861 CCDC85B 11007 204610_s_at 0.4605 0.1015
GSE97050 CCDC85B 11007 A_23_P150249 0.1041 0.7416
SRP007169 CCDC85B 11007 RNAseq -0.8204 0.0225
SRP008496 CCDC85B 11007 RNAseq -0.1818 0.5469
SRP064894 CCDC85B 11007 RNAseq 0.0520 0.8772
SRP133303 CCDC85B 11007 RNAseq 0.3504 0.1803
SRP159526 CCDC85B 11007 RNAseq 0.3011 0.3955
SRP193095 CCDC85B 11007 RNAseq 0.2613 0.2321
SRP219564 CCDC85B 11007 RNAseq -0.0569 0.9329
TCGA CCDC85B 11007 RNAseq 0.1952 0.0124

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by CCDC85B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC85B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC85B 11007 8 5 17
GSE20123 CCDC85B 11007 8 5 17
GSE43470 CCDC85B 11007 6 1 36
GSE46452 CCDC85B 11007 11 3 45
GSE47630 CCDC85B 11007 7 5 28
GSE54993 CCDC85B 11007 3 0 67
GSE54994 CCDC85B 11007 7 5 41
GSE60625 CCDC85B 11007 0 3 8
GSE74703 CCDC85B 11007 4 0 32
GSE74704 CCDC85B 11007 6 3 11
TCGA CCDC85B 11007 23 7 66

Total number of gains: 83; Total number of losses: 37; Total Number of normals: 368.  

 

Somatic mutations of CCDC85B:

 

Generating mutation plots.

 

Highly correlated genes for CCDC85B:

 

Showing top 20/994 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC85BCRTC20.790983303
CCDC85BGHDC0.778206303
CCDC85BPTGFRN0.749447404
CCDC85BPACSIN30.720062303
CCDC85BCAMKK10.717887303
CCDC85BABI20.716756303
CCDC85BGAS2L10.716499303
CCDC85BRFTN20.713976303
CCDC85BKANSL30.712055303
CCDC85BEXOSC60.711385303
CCDC85BA4GALT0.708415303
CCDC85BPHRF10.707597404
CCDC85BNOC2L0.706868303
CCDC85BZC3H12C0.705919303
CCDC85BCDC42EP40.70123404
CCDC85BIRF2BP20.696706303
CCDC85BPOC50.696683404
CCDC85BTRIB10.696242403
CCDC85BDGKD0.6952403
CCDC85BARL20.69418812011

For details and further investigation, click here