FJX1

 

Full name: four-jointed box kinase 1 Alias Symbol: FLJ22416|FLJ25593
Type: protein-coding gene Cytoband: 11p13
Entrez ID: 24147 HGNC ID: HGNC:17166 Ensembl Gene: ENSG00000179431 OMIM ID: 612206
Drug and gene relationship at DGIdb

 

Expression of FJX1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FJX1 24147 219522_at 1.1888 0.2143
GSE20347 FJX1 24147 219522_at 0.9252 0.0010
GSE23400 FJX1 24147 219522_at 0.7479 0.0000
GSE26886 FJX1 24147 219522_at 1.8860 0.0000
GSE29001 FJX1 24147 219522_at 0.9829 0.0091
GSE38129 FJX1 24147 219522_at 1.2515 0.0000
GSE45670 FJX1 24147 219522_at 0.7623 0.0429
GSE53622 FJX1 24147 113793 1.6099 0.0000
GSE53624 FJX1 24147 113793 1.7595 0.0000
GSE63941 FJX1 24147 219522_at -0.7335 0.1608
GSE77861 FJX1 24147 219522_at 0.6520 0.0477
GSE97050 FJX1 24147 A_23_P150693 1.1891 0.1133
SRP007169 FJX1 24147 RNAseq 0.9790 0.1530
SRP008496 FJX1 24147 RNAseq 1.8313 0.0002
SRP064894 FJX1 24147 RNAseq 1.6739 0.0000
SRP133303 FJX1 24147 RNAseq 1.0218 0.0000
SRP159526 FJX1 24147 RNAseq 1.8563 0.0019
SRP219564 FJX1 24147 RNAseq 1.1788 0.0147
TCGA FJX1 24147 RNAseq 0.8519 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  


 

Survival by FJX1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FJX1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FJX1 24147 1 6 23
GSE20123 FJX1 24147 1 5 24
GSE43470 FJX1 24147 3 4 36
GSE46452 FJX1 24147 7 5 47
GSE47630 FJX1 24147 3 10 27
GSE54993 FJX1 24147 3 2 65
GSE54994 FJX1 24147 3 10 40
GSE60625 FJX1 24147 0 0 11
GSE74703 FJX1 24147 2 2 32
GSE74704 FJX1 24147 0 3 17
TCGA FJX1 24147 13 23 60

Total number of gains: 36; Total number of losses: 70; Total Number of normals: 382.  


 

Somatic mutations of FJX1:

 

Generating mutation plots.

 

Highly correlated genes for FJX1:

 

Showing top 20/1609 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FJX1FAM89A0.817853303
FJX1TKT0.783368303
FJX1UCK20.783266303
FJX1SPON20.762926303
FJX1SLC22A50.752981303
FJX1PACS10.748844303
FJX1ZNF7070.739629303
FJX1SH2B20.738709303
FJX1TOP1MT0.738592707
FJX1SSBP40.736581303
FJX1SPSB20.733733303
FJX1ARV10.7315303
FJX1KRTCAP20.727999505
FJX1FMNL20.727911808
FJX1NOP560.724659303
FJX1DKC10.721455303
FJX1TMEM1380.720114707
FJX1TRIM470.719209303
FJX1XPR10.71803707
FJX1SIX50.716465404

For details and further investigation, click here