| Full name: FKBP prolyl isomerase 11 | Alias Symbol: FKBP19 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 51303 | HGNC ID: HGNC:18624 | Ensembl Gene: ENSG00000134285 | OMIM ID: 610571 |
| Drug and gene relationship at DGIdb | |||
Expression of FKBP11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP11 | 51303 | 219117_s_at | 0.2430 | 0.7363 | |
| GSE20347 | FKBP11 | 51303 | 219117_s_at | 0.5807 | 0.0060 | |
| GSE23400 | FKBP11 | 51303 | 219117_s_at | 0.6399 | 0.0000 | |
| GSE26886 | FKBP11 | 51303 | 219117_s_at | 1.5346 | 0.0000 | |
| GSE29001 | FKBP11 | 51303 | 219117_s_at | 0.6732 | 0.0356 | |
| GSE38129 | FKBP11 | 51303 | 219117_s_at | 0.6848 | 0.0003 | |
| GSE45670 | FKBP11 | 51303 | 219117_s_at | 0.1988 | 0.4848 | |
| GSE53622 | FKBP11 | 51303 | 72191 | 0.7886 | 0.0000 | |
| GSE53624 | FKBP11 | 51303 | 72191 | 0.5412 | 0.0000 | |
| GSE63941 | FKBP11 | 51303 | 219117_s_at | -1.1917 | 0.1668 | |
| GSE77861 | FKBP11 | 51303 | 219117_s_at | 0.2801 | 0.5348 | |
| GSE97050 | FKBP11 | 51303 | A_33_P3267296 | 1.2222 | 0.1204 | |
| SRP007169 | FKBP11 | 51303 | RNAseq | 0.8281 | 0.0842 | |
| SRP008496 | FKBP11 | 51303 | RNAseq | 0.9223 | 0.0079 | |
| SRP064894 | FKBP11 | 51303 | RNAseq | 1.0958 | 0.0014 | |
| SRP133303 | FKBP11 | 51303 | RNAseq | 0.3169 | 0.1378 | |
| SRP159526 | FKBP11 | 51303 | RNAseq | 0.6318 | 0.1018 | |
| SRP193095 | FKBP11 | 51303 | RNAseq | 0.2159 | 0.3780 | |
| SRP219564 | FKBP11 | 51303 | RNAseq | 1.0164 | 0.0023 | |
| TCGA | FKBP11 | 51303 | RNAseq | -0.1956 | 0.0377 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by FKBP11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP11 | 51303 | 6 | 1 | 23 | |
| GSE20123 | FKBP11 | 51303 | 6 | 1 | 23 | |
| GSE43470 | FKBP11 | 51303 | 4 | 1 | 38 | |
| GSE46452 | FKBP11 | 51303 | 8 | 1 | 50 | |
| GSE47630 | FKBP11 | 51303 | 11 | 2 | 27 | |
| GSE54993 | FKBP11 | 51303 | 0 | 5 | 65 | |
| GSE54994 | FKBP11 | 51303 | 4 | 1 | 48 | |
| GSE60625 | FKBP11 | 51303 | 0 | 0 | 11 | |
| GSE74703 | FKBP11 | 51303 | 4 | 1 | 31 | |
| GSE74704 | FKBP11 | 51303 | 4 | 1 | 15 | |
| TCGA | FKBP11 | 51303 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 26; Total Number of normals: 399.
Somatic mutations of FKBP11:
Generating mutation plots.
Highly correlated genes for FKBP11:
Showing top 20/785 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP11 | KIAA0895 | 0.778415 | 3 | 0 | 3 |
| FKBP11 | FHL3 | 0.760619 | 3 | 0 | 3 |
| FKBP11 | SLC6A15 | 0.739677 | 3 | 0 | 3 |
| FKBP11 | PDIA5 | 0.737757 | 3 | 0 | 3 |
| FKBP11 | LRCH3 | 0.737571 | 3 | 0 | 3 |
| FKBP11 | NEK8 | 0.705608 | 3 | 0 | 3 |
| FKBP11 | SH2B2 | 0.697112 | 3 | 0 | 3 |
| FKBP11 | SLC39A10 | 0.694364 | 4 | 0 | 4 |
| FKBP11 | NAA38 | 0.693429 | 3 | 0 | 3 |
| FKBP11 | RAC2 | 0.687203 | 7 | 0 | 6 |
| FKBP11 | RICTOR | 0.682168 | 3 | 0 | 3 |
| FKBP11 | TAF4B | 0.679298 | 4 | 0 | 3 |
| FKBP11 | SNAPC4 | 0.678345 | 3 | 0 | 3 |
| FKBP11 | STOML1 | 0.675093 | 4 | 0 | 3 |
| FKBP11 | GLIS2 | 0.673963 | 3 | 0 | 3 |
| FKBP11 | NGF | 0.671342 | 3 | 0 | 3 |
| FKBP11 | EMB | 0.667635 | 3 | 0 | 3 |
| FKBP11 | CERKL | 0.665362 | 3 | 0 | 3 |
| FKBP11 | EID2B | 0.664035 | 3 | 0 | 3 |
| FKBP11 | CYBA | 0.660963 | 8 | 0 | 6 |
For details and further investigation, click here
