| Full name: fukutin related protein | Alias Symbol: LGMD2I|MDC1C | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 79147 | HGNC ID: HGNC:17997 | Ensembl Gene: ENSG00000181027 | OMIM ID: 606596 |
| Drug and gene relationship at DGIdb | |||
Expression of FKRP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKRP | 79147 | 227882_at | 0.3035 | 0.5345 | |
| GSE20347 | FKRP | 79147 | 219853_at | 0.0423 | 0.5107 | |
| GSE23400 | FKRP | 79147 | 219853_at | 0.0414 | 0.1605 | |
| GSE26886 | FKRP | 79147 | 227882_at | 0.2932 | 0.2329 | |
| GSE29001 | FKRP | 79147 | 219853_at | 0.3895 | 0.1339 | |
| GSE38129 | FKRP | 79147 | 219853_at | 0.1297 | 0.2613 | |
| GSE45670 | FKRP | 79147 | 227882_at | 0.1269 | 0.2437 | |
| GSE53622 | FKRP | 79147 | 69311 | -0.1289 | 0.0101 | |
| GSE53624 | FKRP | 79147 | 69311 | -0.2818 | 0.0000 | |
| GSE63941 | FKRP | 79147 | 227882_at | -1.0542 | 0.0221 | |
| GSE77861 | FKRP | 79147 | 227882_at | 0.3844 | 0.0430 | |
| GSE97050 | FKRP | 79147 | A_23_P164946 | -0.2554 | 0.2464 | |
| SRP007169 | FKRP | 79147 | RNAseq | 0.8679 | 0.1729 | |
| SRP064894 | FKRP | 79147 | RNAseq | 0.4040 | 0.0047 | |
| SRP133303 | FKRP | 79147 | RNAseq | 0.4057 | 0.0478 | |
| SRP159526 | FKRP | 79147 | RNAseq | 0.6352 | 0.0210 | |
| SRP193095 | FKRP | 79147 | RNAseq | 0.5506 | 0.0000 | |
| SRP219564 | FKRP | 79147 | RNAseq | 0.2001 | 0.5570 | |
| TCGA | FKRP | 79147 | RNAseq | -0.0385 | 0.5009 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FKRP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKRP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKRP | 79147 | 4 | 4 | 22 | |
| GSE20123 | FKRP | 79147 | 4 | 3 | 23 | |
| GSE43470 | FKRP | 79147 | 3 | 11 | 29 | |
| GSE46452 | FKRP | 79147 | 45 | 1 | 13 | |
| GSE47630 | FKRP | 79147 | 8 | 7 | 25 | |
| GSE54993 | FKRP | 79147 | 17 | 4 | 49 | |
| GSE54994 | FKRP | 79147 | 5 | 13 | 35 | |
| GSE60625 | FKRP | 79147 | 9 | 0 | 2 | |
| GSE74703 | FKRP | 79147 | 3 | 7 | 26 | |
| GSE74704 | FKRP | 79147 | 4 | 1 | 15 | |
| TCGA | FKRP | 79147 | 16 | 16 | 64 |
Total number of gains: 118; Total number of losses: 67; Total Number of normals: 303.
Somatic mutations of FKRP:
Generating mutation plots.
Highly correlated genes for FKRP:
Showing top 20/142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKRP | KCTD13 | 0.65599 | 4 | 0 | 3 |
| FKRP | FGFR1 | 0.655544 | 3 | 0 | 3 |
| FKRP | MGP | 0.630745 | 4 | 0 | 4 |
| FKRP | FLOT1 | 0.624364 | 4 | 0 | 3 |
| FKRP | LINC01252 | 0.621988 | 3 | 0 | 3 |
| FKRP | TMSB15B | 0.618563 | 3 | 0 | 3 |
| FKRP | SGCD | 0.613966 | 3 | 0 | 3 |
| FKRP | JUN | 0.611322 | 3 | 0 | 3 |
| FKRP | KPNA6 | 0.610192 | 4 | 0 | 4 |
| FKRP | RILPL1 | 0.609504 | 4 | 0 | 3 |
| FKRP | TPM2 | 0.607523 | 3 | 0 | 3 |
| FKRP | NCKAP5L | 0.605055 | 4 | 0 | 3 |
| FKRP | NFIC | 0.599409 | 5 | 0 | 3 |
| FKRP | COPG1 | 0.599318 | 3 | 0 | 3 |
| FKRP | CLEC11A | 0.597477 | 3 | 0 | 3 |
| FKRP | SF3A2 | 0.596571 | 5 | 0 | 3 |
| FKRP | TBCB | 0.595783 | 6 | 0 | 4 |
| FKRP | GLIS3 | 0.592281 | 3 | 0 | 3 |
| FKRP | ARHGEF2 | 0.584734 | 5 | 0 | 3 |
| FKRP | TUBA1A | 0.583976 | 4 | 0 | 4 |
For details and further investigation, click here
