| Full name: stimulator of chondrogenesis 1 | Alias Symbol: SCRG-1 | ||
| Type: protein-coding gene | Cytoband: 4q34.1 | ||
| Entrez ID: 11341 | HGNC ID: HGNC:17036 | Ensembl Gene: ENSG00000164106 | OMIM ID: 603163 |
| Drug and gene relationship at DGIdb | |||
Expression of SCRG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCRG1 | 11341 | 205475_at | -0.7152 | 0.4581 | |
| GSE20347 | SCRG1 | 11341 | 205475_at | -0.0208 | 0.8899 | |
| GSE23400 | SCRG1 | 11341 | 205475_at | 0.0880 | 0.6252 | |
| GSE26886 | SCRG1 | 11341 | 205475_at | -0.0800 | 0.5803 | |
| GSE29001 | SCRG1 | 11341 | 205475_at | 0.0034 | 0.9883 | |
| GSE38129 | SCRG1 | 11341 | 205475_at | -0.4416 | 0.3567 | |
| GSE45670 | SCRG1 | 11341 | 205475_at | -0.6630 | 0.0000 | |
| GSE53622 | SCRG1 | 11341 | 15768 | -0.2167 | 0.0044 | |
| GSE53624 | SCRG1 | 11341 | 15768 | -0.0803 | 0.4088 | |
| GSE63941 | SCRG1 | 11341 | 205475_at | -0.3641 | 0.0498 | |
| GSE77861 | SCRG1 | 11341 | 205475_at | -0.0440 | 0.7631 | |
| GSE97050 | SCRG1 | 11341 | A_23_P167159 | 0.0864 | 0.9369 | |
| SRP064894 | SCRG1 | 11341 | RNAseq | 1.5231 | 0.0003 | |
| SRP133303 | SCRG1 | 11341 | RNAseq | 0.0054 | 0.9808 | |
| SRP193095 | SCRG1 | 11341 | RNAseq | 0.1251 | 0.3638 | |
| SRP219564 | SCRG1 | 11341 | RNAseq | -0.7962 | 0.5114 | |
| TCGA | SCRG1 | 11341 | RNAseq | -1.0871 | 0.1422 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SCRG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCRG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCRG1 | 11341 | 2 | 10 | 18 | |
| GSE20123 | SCRG1 | 11341 | 2 | 10 | 18 | |
| GSE43470 | SCRG1 | 11341 | 0 | 13 | 30 | |
| GSE46452 | SCRG1 | 11341 | 1 | 36 | 22 | |
| GSE47630 | SCRG1 | 11341 | 0 | 22 | 18 | |
| GSE54993 | SCRG1 | 11341 | 10 | 0 | 60 | |
| GSE54994 | SCRG1 | 11341 | 2 | 12 | 39 | |
| GSE60625 | SCRG1 | 11341 | 0 | 0 | 11 | |
| GSE74703 | SCRG1 | 11341 | 0 | 11 | 25 | |
| GSE74704 | SCRG1 | 11341 | 1 | 5 | 14 | |
| TCGA | SCRG1 | 11341 | 10 | 36 | 50 |
Total number of gains: 28; Total number of losses: 155; Total Number of normals: 305.
Somatic mutations of SCRG1:
Generating mutation plots.
Highly correlated genes for SCRG1:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCRG1 | FILIP1 | 0.794597 | 3 | 0 | 3 |
| SCRG1 | ANGPTL1 | 0.754694 | 4 | 0 | 4 |
| SCRG1 | ID4 | 0.738346 | 3 | 0 | 3 |
| SCRG1 | CTSW | 0.737929 | 3 | 0 | 3 |
| SCRG1 | SYNM | 0.735548 | 8 | 0 | 8 |
| SCRG1 | SLIT2 | 0.734879 | 6 | 0 | 6 |
| SCRG1 | PPP1R12B | 0.731004 | 7 | 0 | 7 |
| SCRG1 | SLC4A4 | 0.722255 | 3 | 0 | 3 |
| SCRG1 | ARHGEF9 | 0.72054 | 4 | 0 | 4 |
| SCRG1 | STK38L | 0.717614 | 3 | 0 | 3 |
| SCRG1 | SMOC2 | 0.711352 | 3 | 0 | 3 |
| SCRG1 | TSHZ1 | 0.708037 | 3 | 0 | 3 |
| SCRG1 | STARD13 | 0.707436 | 6 | 0 | 5 |
| SCRG1 | ASPA | 0.703062 | 5 | 0 | 4 |
| SCRG1 | NDUFB2 | 0.700992 | 3 | 0 | 3 |
| SCRG1 | SYNE1 | 0.700272 | 5 | 0 | 5 |
| SCRG1 | DIXDC1 | 0.700032 | 6 | 0 | 6 |
| SCRG1 | PLN | 0.698147 | 9 | 0 | 8 |
| SCRG1 | CNN1 | 0.695789 | 9 | 0 | 8 |
| SCRG1 | KCNT2 | 0.694206 | 4 | 0 | 3 |
For details and further investigation, click here
