| Full name: FERM domain containing 4A | Alias Symbol: FLJ10210|KIAA1294|bA295P9.4 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 55691 | HGNC ID: HGNC:25491 | Ensembl Gene: ENSG00000151474 | OMIM ID: 616305 |
| Drug and gene relationship at DGIdb | |||
Expression of FRMD4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRMD4A | 55691 | 225167_at | -0.2869 | 0.4419 | |
| GSE20347 | FRMD4A | 55691 | 208475_at | -0.1568 | 0.5125 | |
| GSE23400 | FRMD4A | 55691 | 208475_at | -0.0200 | 0.5949 | |
| GSE26886 | FRMD4A | 55691 | 225163_at | -1.2168 | 0.0038 | |
| GSE29001 | FRMD4A | 55691 | 208475_at | -0.0028 | 0.9941 | |
| GSE38129 | FRMD4A | 55691 | 208476_s_at | -0.3340 | 0.0773 | |
| GSE45670 | FRMD4A | 55691 | 225163_at | -0.6630 | 0.0075 | |
| GSE53622 | FRMD4A | 55691 | 54888 | -0.3286 | 0.0054 | |
| GSE53624 | FRMD4A | 55691 | 99987 | -0.1253 | 0.3828 | |
| GSE63941 | FRMD4A | 55691 | 225168_at | -0.2740 | 0.7277 | |
| GSE77861 | FRMD4A | 55691 | 225168_at | -0.5103 | 0.0389 | |
| GSE97050 | FRMD4A | 55691 | A_23_P22352 | -0.1338 | 0.6701 | |
| SRP007169 | FRMD4A | 55691 | RNAseq | -0.5725 | 0.1743 | |
| SRP008496 | FRMD4A | 55691 | RNAseq | -0.4860 | 0.2372 | |
| SRP064894 | FRMD4A | 55691 | RNAseq | 0.2444 | 0.1978 | |
| SRP133303 | FRMD4A | 55691 | RNAseq | -0.6323 | 0.0017 | |
| SRP193095 | FRMD4A | 55691 | RNAseq | -0.2630 | 0.0718 | |
| SRP219564 | FRMD4A | 55691 | RNAseq | -0.1942 | 0.6627 | |
| TCGA | FRMD4A | 55691 | RNAseq | -0.1128 | 0.1932 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FRMD4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRMD4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMD4A | 55691 | 3 | 8 | 19 | |
| GSE20123 | FRMD4A | 55691 | 3 | 7 | 20 | |
| GSE43470 | FRMD4A | 55691 | 3 | 5 | 35 | |
| GSE46452 | FRMD4A | 55691 | 1 | 14 | 44 | |
| GSE47630 | FRMD4A | 55691 | 6 | 14 | 20 | |
| GSE54993 | FRMD4A | 55691 | 11 | 0 | 59 | |
| GSE54994 | FRMD4A | 55691 | 4 | 9 | 40 | |
| GSE60625 | FRMD4A | 55691 | 0 | 0 | 11 | |
| GSE74703 | FRMD4A | 55691 | 2 | 3 | 31 | |
| GSE74704 | FRMD4A | 55691 | 0 | 6 | 14 | |
| TCGA | FRMD4A | 55691 | 19 | 26 | 51 |
Total number of gains: 52; Total number of losses: 92; Total Number of normals: 344.
Somatic mutations of FRMD4A:
Generating mutation plots.
Highly correlated genes for FRMD4A:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMD4A | CCDC12 | 0.719369 | 3 | 0 | 3 |
| FRMD4A | C2CD2L | 0.710835 | 3 | 0 | 3 |
| FRMD4A | RBPJL | 0.686171 | 3 | 0 | 3 |
| FRMD4A | HSPB8 | 0.670964 | 3 | 0 | 3 |
| FRMD4A | CRYL1 | 0.669726 | 3 | 0 | 3 |
| FRMD4A | HERC6 | 0.665482 | 3 | 0 | 3 |
| FRMD4A | ZNF784 | 0.663742 | 3 | 0 | 3 |
| FRMD4A | INPP1 | 0.659972 | 4 | 0 | 3 |
| FRMD4A | ASCC2 | 0.659222 | 3 | 0 | 3 |
| FRMD4A | TRIM6 | 0.657326 | 3 | 0 | 3 |
| FRMD4A | FBXW5 | 0.657293 | 3 | 0 | 3 |
| FRMD4A | TP53I3 | 0.655134 | 3 | 0 | 3 |
| FRMD4A | MECOM | 0.65402 | 5 | 0 | 4 |
| FRMD4A | SEC24C | 0.643411 | 4 | 0 | 4 |
| FRMD4A | CPPED1 | 0.638335 | 3 | 0 | 3 |
| FRMD4A | SUOX | 0.638023 | 4 | 0 | 3 |
| FRMD4A | TIFA | 0.637548 | 4 | 0 | 3 |
| FRMD4A | GPD1L | 0.636818 | 5 | 0 | 5 |
| FRMD4A | PPM1K | 0.632968 | 5 | 0 | 5 |
| FRMD4A | SLC44A2 | 0.630856 | 3 | 0 | 3 |
For details and further investigation, click here
