| Full name: SEC24 homolog C, COPII coat complex component | Alias Symbol: KIAA0079 | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 9632 | HGNC ID: HGNC:10705 | Ensembl Gene: ENSG00000176986 | OMIM ID: 607185 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC24C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC24C | 9632 | 202361_at | -0.2110 | 0.7047 | |
| GSE20347 | SEC24C | 9632 | 202361_at | -0.6734 | 0.0000 | |
| GSE23400 | SEC24C | 9632 | 202361_at | -0.5743 | 0.0000 | |
| GSE26886 | SEC24C | 9632 | 202361_at | -2.2237 | 0.0000 | |
| GSE29001 | SEC24C | 9632 | 202361_at | -0.8450 | 0.0073 | |
| GSE38129 | SEC24C | 9632 | 202361_at | -0.4280 | 0.0005 | |
| GSE45670 | SEC24C | 9632 | 202361_at | -0.1446 | 0.4724 | |
| GSE53622 | SEC24C | 9632 | 92992 | -0.5849 | 0.0000 | |
| GSE53624 | SEC24C | 9632 | 92992 | -0.5228 | 0.0000 | |
| GSE63941 | SEC24C | 9632 | 202361_at | -0.1971 | 0.6600 | |
| GSE77861 | SEC24C | 9632 | 202361_at | -0.6405 | 0.0005 | |
| GSE97050 | SEC24C | 9632 | A_33_P3317123 | 0.0716 | 0.8191 | |
| SRP007169 | SEC24C | 9632 | RNAseq | -1.9510 | 0.0000 | |
| SRP008496 | SEC24C | 9632 | RNAseq | -1.7493 | 0.0000 | |
| SRP064894 | SEC24C | 9632 | RNAseq | -1.1150 | 0.0000 | |
| SRP133303 | SEC24C | 9632 | RNAseq | -0.4568 | 0.0005 | |
| SRP159526 | SEC24C | 9632 | RNAseq | -0.9817 | 0.0000 | |
| SRP193095 | SEC24C | 9632 | RNAseq | -0.7454 | 0.0000 | |
| SRP219564 | SEC24C | 9632 | RNAseq | -0.7674 | 0.0387 | |
| TCGA | SEC24C | 9632 | RNAseq | -0.0735 | 0.1007 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SEC24C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC24C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC24C | 9632 | 3 | 4 | 23 | |
| GSE20123 | SEC24C | 9632 | 3 | 3 | 24 | |
| GSE43470 | SEC24C | 9632 | 1 | 8 | 34 | |
| GSE46452 | SEC24C | 9632 | 0 | 11 | 48 | |
| GSE47630 | SEC24C | 9632 | 2 | 14 | 24 | |
| GSE54993 | SEC24C | 9632 | 7 | 0 | 63 | |
| GSE54994 | SEC24C | 9632 | 2 | 10 | 41 | |
| GSE60625 | SEC24C | 9632 | 0 | 0 | 11 | |
| GSE74703 | SEC24C | 9632 | 1 | 5 | 30 | |
| GSE74704 | SEC24C | 9632 | 1 | 1 | 18 | |
| TCGA | SEC24C | 9632 | 11 | 23 | 62 |
Total number of gains: 31; Total number of losses: 79; Total Number of normals: 378.
Somatic mutations of SEC24C:
Generating mutation plots.
Highly correlated genes for SEC24C:
Showing top 20/1294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC24C | ZNRF1 | 0.770515 | 5 | 0 | 5 |
| SEC24C | ASCC2 | 0.760641 | 11 | 0 | 11 |
| SEC24C | MMEL1 | 0.752844 | 4 | 0 | 4 |
| SEC24C | ANKRD22 | 0.746519 | 4 | 0 | 4 |
| SEC24C | CSDE1 | 0.740095 | 3 | 0 | 3 |
| SEC24C | VSIG10L | 0.740032 | 5 | 0 | 5 |
| SEC24C | NT5C2 | 0.736437 | 11 | 0 | 11 |
| SEC24C | PCBP1-AS1 | 0.73257 | 3 | 0 | 3 |
| SEC24C | ESPL1 | 0.73014 | 10 | 0 | 10 |
| SEC24C | FUT3 | 0.729751 | 11 | 0 | 11 |
| SEC24C | MFSD5 | 0.729234 | 11 | 0 | 10 |
| SEC24C | TTC9 | 0.726987 | 11 | 0 | 10 |
| SEC24C | SFTA2 | 0.725552 | 4 | 0 | 4 |
| SEC24C | NAGK | 0.725252 | 11 | 0 | 11 |
| SEC24C | GCHFR | 0.722409 | 8 | 0 | 8 |
| SEC24C | TMEM254 | 0.716666 | 10 | 0 | 9 |
| SEC24C | CWH43 | 0.714109 | 9 | 0 | 8 |
| SEC24C | TMED3 | 0.71334 | 10 | 0 | 10 |
| SEC24C | EPS8L2 | 0.712405 | 10 | 0 | 10 |
| SEC24C | ARHGAP27 | 0.710494 | 7 | 0 | 7 |
For details and further investigation, click here
