| Full name: fucosyltransferase 2 | Alias Symbol: sej|Se2|SEC2 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 2524 | HGNC ID: HGNC:4013 | Ensembl Gene: ENSG00000176920 | OMIM ID: 182100 |
| Drug and gene relationship at DGIdb | |||
Expression of FUT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUT2 | 2524 | 210608_s_at | -1.7506 | 0.1561 | |
| GSE20347 | FUT2 | 2524 | 210608_s_at | -1.6092 | 0.0000 | |
| GSE23400 | FUT2 | 2524 | 210608_s_at | -1.3018 | 0.0000 | |
| GSE26886 | FUT2 | 2524 | 210608_s_at | -1.8722 | 0.0000 | |
| GSE29001 | FUT2 | 2524 | 210608_s_at | -1.0542 | 0.0006 | |
| GSE38129 | FUT2 | 2524 | 210608_s_at | -1.2158 | 0.0021 | |
| GSE45670 | FUT2 | 2524 | 210608_s_at | 0.0491 | 0.8830 | |
| GSE63941 | FUT2 | 2524 | 208505_s_at | 0.6151 | 0.1512 | |
| GSE77861 | FUT2 | 2524 | 210608_s_at | -0.6145 | 0.1864 | |
| GSE97050 | FUT2 | 2524 | A_24_P942969 | -0.2990 | 0.4263 | |
| SRP007169 | FUT2 | 2524 | RNAseq | -2.2207 | 0.0000 | |
| SRP008496 | FUT2 | 2524 | RNAseq | -2.6417 | 0.0000 | |
| SRP064894 | FUT2 | 2524 | RNAseq | -2.0736 | 0.0000 | |
| SRP133303 | FUT2 | 2524 | RNAseq | -1.5749 | 0.0000 | |
| SRP159526 | FUT2 | 2524 | RNAseq | -2.1178 | 0.0004 | |
| SRP193095 | FUT2 | 2524 | RNAseq | -1.4245 | 0.0000 | |
| SRP219564 | FUT2 | 2524 | RNAseq | -2.0622 | 0.0225 | |
| TCGA | FUT2 | 2524 | RNAseq | -0.1864 | 0.2866 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by FUT2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FUT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUT2 | 2524 | 4 | 4 | 22 | |
| GSE20123 | FUT2 | 2524 | 4 | 3 | 23 | |
| GSE43470 | FUT2 | 2524 | 4 | 10 | 29 | |
| GSE46452 | FUT2 | 2524 | 45 | 1 | 13 | |
| GSE47630 | FUT2 | 2524 | 9 | 6 | 25 | |
| GSE54993 | FUT2 | 2524 | 17 | 4 | 49 | |
| GSE54994 | FUT2 | 2524 | 4 | 14 | 35 | |
| GSE60625 | FUT2 | 2524 | 9 | 0 | 2 | |
| GSE74703 | FUT2 | 2524 | 4 | 7 | 25 | |
| GSE74704 | FUT2 | 2524 | 4 | 1 | 15 | |
| TCGA | FUT2 | 2524 | 14 | 18 | 64 |
Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.
Somatic mutations of FUT2:
Generating mutation plots.
Highly correlated genes for FUT2:
Showing top 20/1262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUT2 | TGM1 | 0.782166 | 10 | 0 | 9 |
| FUT2 | CLIC3 | 0.769173 | 10 | 0 | 9 |
| FUT2 | TMPRSS11D | 0.767269 | 10 | 0 | 10 |
| FUT2 | CEACAM1 | 0.764319 | 9 | 0 | 8 |
| FUT2 | FUT3 | 0.758423 | 10 | 0 | 10 |
| FUT2 | SCEL | 0.756453 | 9 | 0 | 9 |
| FUT2 | SERPINB1 | 0.756139 | 10 | 0 | 9 |
| FUT2 | NLRX1 | 0.750004 | 9 | 0 | 9 |
| FUT2 | MAST4 | 0.742886 | 7 | 0 | 7 |
| FUT2 | FMO2 | 0.740685 | 9 | 0 | 9 |
| FUT2 | SPAG17 | 0.740512 | 5 | 0 | 5 |
| FUT2 | PLEKHM1 | 0.736754 | 10 | 0 | 9 |
| FUT2 | XG | 0.735313 | 3 | 0 | 3 |
| FUT2 | TMEM40 | 0.735042 | 11 | 0 | 10 |
| FUT2 | PSCA | 0.733324 | 8 | 0 | 8 |
| FUT2 | GLTP | 0.733045 | 10 | 0 | 9 |
| FUT2 | KLK8 | 0.732257 | 10 | 0 | 10 |
| FUT2 | CEACAM5 | 0.730405 | 9 | 0 | 9 |
| FUT2 | PRSS27 | 0.729121 | 5 | 0 | 5 |
| FUT2 | PRSS3 | 0.727697 | 10 | 0 | 9 |
For details and further investigation, click here
