| Full name: Rho GTPase activating protein 20 | Alias Symbol: KIAA1391 | ||
| Type: protein-coding gene | Cytoband: 11q22.3-q23.1 | ||
| Entrez ID: 57569 | HGNC ID: HGNC:18357 | Ensembl Gene: ENSG00000137727 | OMIM ID: 609568 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP20 | 57569 | 228368_at | -1.1076 | 0.0331 | |
| GSE26886 | ARHGAP20 | 57569 | 1555020_a_at | -0.2201 | 0.0808 | |
| GSE45670 | ARHGAP20 | 57569 | 1555020_a_at | 0.2177 | 0.0334 | |
| GSE53622 | ARHGAP20 | 57569 | 96345 | -1.7481 | 0.0000 | |
| GSE53624 | ARHGAP20 | 57569 | 96345 | -1.3877 | 0.0000 | |
| GSE63941 | ARHGAP20 | 57569 | 228368_at | -4.9691 | 0.0000 | |
| GSE77861 | ARHGAP20 | 57569 | 1555020_a_at | -0.0771 | 0.4714 | |
| SRP007169 | ARHGAP20 | 57569 | RNAseq | -1.5117 | 0.0107 | |
| SRP064894 | ARHGAP20 | 57569 | RNAseq | -0.4063 | 0.3197 | |
| SRP133303 | ARHGAP20 | 57569 | RNAseq | -1.1923 | 0.0030 | |
| SRP159526 | ARHGAP20 | 57569 | RNAseq | -1.2897 | 0.0316 | |
| SRP193095 | ARHGAP20 | 57569 | RNAseq | -1.0505 | 0.0000 | |
| SRP219564 | ARHGAP20 | 57569 | RNAseq | 0.1748 | 0.7604 | |
| TCGA | ARHGAP20 | 57569 | RNAseq | -0.4835 | 0.0164 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by ARHGAP20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP20 | 57569 | 0 | 13 | 17 | |
| GSE20123 | ARHGAP20 | 57569 | 0 | 12 | 18 | |
| GSE43470 | ARHGAP20 | 57569 | 2 | 6 | 35 | |
| GSE46452 | ARHGAP20 | 57569 | 3 | 26 | 30 | |
| GSE47630 | ARHGAP20 | 57569 | 2 | 19 | 19 | |
| GSE54993 | ARHGAP20 | 57569 | 10 | 0 | 60 | |
| GSE54994 | ARHGAP20 | 57569 | 5 | 19 | 29 | |
| GSE60625 | ARHGAP20 | 57569 | 0 | 3 | 8 | |
| GSE74703 | ARHGAP20 | 57569 | 1 | 4 | 31 | |
| GSE74704 | ARHGAP20 | 57569 | 0 | 8 | 12 | |
| TCGA | ARHGAP20 | 57569 | 6 | 47 | 43 |
Total number of gains: 29; Total number of losses: 157; Total Number of normals: 302.
Somatic mutations of ARHGAP20:
Generating mutation plots.
Highly correlated genes for ARHGAP20:
Showing top 20/399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP20 | RSPO2 | 0.778706 | 3 | 0 | 3 |
| ARHGAP20 | IL33 | 0.7667 | 4 | 0 | 4 |
| ARHGAP20 | PTN | 0.755836 | 3 | 0 | 3 |
| ARHGAP20 | SHISA3 | 0.755207 | 3 | 0 | 3 |
| ARHGAP20 | CYYR1 | 0.719212 | 3 | 0 | 3 |
| ARHGAP20 | ZCWPW2 | 0.711853 | 4 | 0 | 4 |
| ARHGAP20 | SPATA18 | 0.709135 | 3 | 0 | 3 |
| ARHGAP20 | IL6ST | 0.699858 | 4 | 0 | 4 |
| ARHGAP20 | ZNF471 | 0.699239 | 3 | 0 | 3 |
| ARHGAP20 | PRICKLE2 | 0.695866 | 4 | 0 | 4 |
| ARHGAP20 | XYLT1 | 0.69363 | 5 | 0 | 5 |
| ARHGAP20 | SLC18A2 | 0.690299 | 3 | 0 | 3 |
| ARHGAP20 | ARL6IP5 | 0.683166 | 5 | 0 | 4 |
| ARHGAP20 | MEIS1 | 0.682946 | 4 | 0 | 4 |
| ARHGAP20 | CLDN5 | 0.681523 | 3 | 0 | 3 |
| ARHGAP20 | LY6G6C | 0.681412 | 3 | 0 | 3 |
| ARHGAP20 | PLAC9 | 0.681311 | 3 | 0 | 3 |
| ARHGAP20 | PLCXD3 | 0.679351 | 3 | 0 | 3 |
| ARHGAP20 | DDAH1 | 0.678769 | 4 | 0 | 4 |
| ARHGAP20 | LRFN5 | 0.675245 | 4 | 0 | 4 |
For details and further investigation, click here
