| Full name: FXYD domain containing ion transport regulator 5 | Alias Symbol: OIT2 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 53827 | HGNC ID: HGNC:4029 | Ensembl Gene: ENSG00000089327 | OMIM ID: 606669 |
| Drug and gene relationship at DGIdb | |||
Expression of FXYD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FXYD5 | 53827 | 218084_x_at | -0.1489 | 0.8592 | |
| GSE20347 | FXYD5 | 53827 | 218084_x_at | -0.3482 | 0.2440 | |
| GSE23400 | FXYD5 | 53827 | 218084_x_at | -0.0368 | 0.8146 | |
| GSE26886 | FXYD5 | 53827 | 218084_x_at | 0.2930 | 0.4346 | |
| GSE29001 | FXYD5 | 53827 | 218084_x_at | -0.1277 | 0.7562 | |
| GSE38129 | FXYD5 | 53827 | 218084_x_at | -0.1923 | 0.4290 | |
| GSE45670 | FXYD5 | 53827 | 218084_x_at | 0.6448 | 0.0139 | |
| GSE53622 | FXYD5 | 53827 | 61503 | 0.4880 | 0.0000 | |
| GSE53624 | FXYD5 | 53827 | 61503 | 0.4929 | 0.0000 | |
| GSE63941 | FXYD5 | 53827 | 218084_x_at | 1.5350 | 0.1579 | |
| GSE77861 | FXYD5 | 53827 | 218084_x_at | 0.5002 | 0.2780 | |
| GSE97050 | FXYD5 | 53827 | A_24_P194081 | 1.3374 | 0.1065 | |
| SRP007169 | FXYD5 | 53827 | RNAseq | -1.2143 | 0.0250 | |
| SRP008496 | FXYD5 | 53827 | RNAseq | -0.7604 | 0.0254 | |
| SRP064894 | FXYD5 | 53827 | RNAseq | 1.1249 | 0.0004 | |
| SRP133303 | FXYD5 | 53827 | RNAseq | 0.1835 | 0.4281 | |
| SRP159526 | FXYD5 | 53827 | RNAseq | -0.5018 | 0.0806 | |
| SRP193095 | FXYD5 | 53827 | RNAseq | 0.5101 | 0.0364 | |
| SRP219564 | FXYD5 | 53827 | RNAseq | 0.7718 | 0.1246 | |
| TCGA | FXYD5 | 53827 | RNAseq | 0.3361 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by FXYD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FXYD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FXYD5 | 53827 | 6 | 4 | 20 | |
| GSE20123 | FXYD5 | 53827 | 6 | 3 | 21 | |
| GSE43470 | FXYD5 | 53827 | 3 | 7 | 33 | |
| GSE46452 | FXYD5 | 53827 | 48 | 1 | 10 | |
| GSE47630 | FXYD5 | 53827 | 9 | 5 | 26 | |
| GSE54993 | FXYD5 | 53827 | 17 | 3 | 50 | |
| GSE54994 | FXYD5 | 53827 | 8 | 9 | 36 | |
| GSE60625 | FXYD5 | 53827 | 9 | 0 | 2 | |
| GSE74703 | FXYD5 | 53827 | 3 | 4 | 29 | |
| GSE74704 | FXYD5 | 53827 | 6 | 1 | 13 | |
| TCGA | FXYD5 | 53827 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of FXYD5:
Generating mutation plots.
Highly correlated genes for FXYD5:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FXYD5 | CLEC2D | 0.745706 | 3 | 0 | 3 |
| FXYD5 | KIAA0319L | 0.68752 | 3 | 0 | 3 |
| FXYD5 | PPARD | 0.683906 | 3 | 0 | 3 |
| FXYD5 | TMEM107 | 0.679969 | 4 | 0 | 4 |
| FXYD5 | PYHIN1 | 0.663055 | 4 | 0 | 3 |
| FXYD5 | JAK3 | 0.659335 | 4 | 0 | 3 |
| FXYD5 | CDH3 | 0.64788 | 5 | 0 | 4 |
| FXYD5 | PTK7 | 0.646271 | 5 | 0 | 4 |
| FXYD5 | PREX1 | 0.645525 | 3 | 0 | 3 |
| FXYD5 | LIMK1 | 0.636262 | 4 | 0 | 3 |
| FXYD5 | MMP14 | 0.63301 | 4 | 0 | 3 |
| FXYD5 | LAMB3 | 0.632389 | 5 | 0 | 4 |
| FXYD5 | TFAP2A | 0.631579 | 4 | 0 | 3 |
| FXYD5 | CD22 | 0.629017 | 4 | 0 | 3 |
| FXYD5 | LPAR3 | 0.625841 | 4 | 0 | 3 |
| FXYD5 | MRPS12 | 0.623423 | 3 | 0 | 3 |
| FXYD5 | TSTA3 | 0.618928 | 4 | 0 | 3 |
| FXYD5 | FSCN1 | 0.617203 | 5 | 0 | 4 |
| FXYD5 | NRM | 0.615585 | 6 | 0 | 5 |
| FXYD5 | ELMO1 | 0.61247 | 3 | 0 | 3 |
For details and further investigation, click here
