| Full name: C-type lectin domain family 2 member D | Alias Symbol: LLT1|CLAX|OCIL | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 29121 | HGNC ID: HGNC:14351 | Ensembl Gene: ENSG00000069493 | OMIM ID: 605659 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC2D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC2D | 29121 | 233500_x_at | 0.0304 | 0.9771 | |
| GSE20347 | CLEC2D | 29121 | 220132_s_at | 0.0678 | 0.2411 | |
| GSE23400 | CLEC2D | 29121 | 220132_s_at | 0.1032 | 0.0000 | |
| GSE26886 | CLEC2D | 29121 | 233500_x_at | 0.0575 | 0.7564 | |
| GSE29001 | CLEC2D | 29121 | 220132_s_at | 0.2539 | 0.0408 | |
| GSE38129 | CLEC2D | 29121 | 220132_s_at | 0.1191 | 0.0237 | |
| GSE45670 | CLEC2D | 29121 | 235522_at | 0.1033 | 0.6028 | |
| GSE53622 | CLEC2D | 29121 | 85696 | 0.5006 | 0.0001 | |
| GSE53624 | CLEC2D | 29121 | 85696 | 0.1734 | 0.1735 | |
| GSE63941 | CLEC2D | 29121 | 233500_x_at | 0.2274 | 0.7314 | |
| GSE77861 | CLEC2D | 29121 | 233500_x_at | -0.0830 | 0.4902 | |
| GSE97050 | CLEC2D | 29121 | A_32_P80068 | 0.2757 | 0.3524 | |
| SRP007169 | CLEC2D | 29121 | RNAseq | 0.1856 | 0.7467 | |
| SRP008496 | CLEC2D | 29121 | RNAseq | 0.0637 | 0.8634 | |
| SRP064894 | CLEC2D | 29121 | RNAseq | 0.5122 | 0.0183 | |
| SRP133303 | CLEC2D | 29121 | RNAseq | 0.0626 | 0.7544 | |
| SRP159526 | CLEC2D | 29121 | RNAseq | -0.1797 | 0.7180 | |
| SRP193095 | CLEC2D | 29121 | RNAseq | 0.1999 | 0.2082 | |
| SRP219564 | CLEC2D | 29121 | RNAseq | 0.6020 | 0.1031 | |
| TCGA | CLEC2D | 29121 | RNAseq | 0.2290 | 0.0016 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLEC2D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC2D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC2D | 29121 | 6 | 3 | 21 | |
| GSE20123 | CLEC2D | 29121 | 6 | 3 | 21 | |
| GSE43470 | CLEC2D | 29121 | 8 | 3 | 32 | |
| GSE46452 | CLEC2D | 29121 | 10 | 1 | 48 | |
| GSE47630 | CLEC2D | 29121 | 14 | 2 | 24 | |
| GSE54993 | CLEC2D | 29121 | 1 | 10 | 59 | |
| GSE54994 | CLEC2D | 29121 | 9 | 2 | 42 | |
| GSE60625 | CLEC2D | 29121 | 0 | 1 | 10 | |
| GSE74703 | CLEC2D | 29121 | 8 | 2 | 26 | |
| GSE74704 | CLEC2D | 29121 | 4 | 2 | 14 | |
| TCGA | CLEC2D | 29121 | 39 | 6 | 51 |
Total number of gains: 105; Total number of losses: 35; Total Number of normals: 348.
Somatic mutations of CLEC2D:
Generating mutation plots.
Highly correlated genes for CLEC2D:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC2D | FXYD5 | 0.745706 | 3 | 0 | 3 |
| CLEC2D | GNGT2 | 0.721037 | 3 | 0 | 3 |
| CLEC2D | PAPSS2 | 0.721011 | 3 | 0 | 3 |
| CLEC2D | CHST11 | 0.693486 | 3 | 0 | 3 |
| CLEC2D | GLRX | 0.692807 | 3 | 0 | 3 |
| CLEC2D | WBP11 | 0.676825 | 3 | 0 | 3 |
| CLEC2D | PIK3AP1 | 0.673731 | 4 | 0 | 3 |
| CLEC2D | PALB2 | 0.671027 | 3 | 0 | 3 |
| CLEC2D | CD37 | 0.668784 | 4 | 0 | 3 |
| CLEC2D | TMED5 | 0.660157 | 3 | 0 | 3 |
| CLEC2D | ATP8B4 | 0.649802 | 3 | 0 | 3 |
| CLEC2D | ST8SIA4 | 0.645211 | 4 | 0 | 3 |
| CLEC2D | CSF1R | 0.641482 | 5 | 0 | 4 |
| CLEC2D | CD300A | 0.641119 | 6 | 0 | 5 |
| CLEC2D | CD53 | 0.636637 | 7 | 0 | 6 |
| CLEC2D | MS4A6A | 0.632535 | 4 | 0 | 3 |
| CLEC2D | CD38 | 0.632223 | 5 | 0 | 4 |
| CLEC2D | PDE4B | 0.631527 | 4 | 0 | 3 |
| CLEC2D | ZNF281 | 0.629755 | 3 | 0 | 3 |
| CLEC2D | IL7R | 0.62825 | 5 | 0 | 3 |
For details and further investigation, click here
