| Full name: perilipin 3 | Alias Symbol: TIP47|PP17 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10226 | HGNC ID: HGNC:16893 | Ensembl Gene: ENSG00000105355 | OMIM ID: 602702 |
| Drug and gene relationship at DGIdb | |||
Expression of PLIN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLIN3 | 10226 | 202122_s_at | -0.7001 | 0.4519 | |
| GSE20347 | PLIN3 | 10226 | 202122_s_at | -1.2177 | 0.0000 | |
| GSE23400 | PLIN3 | 10226 | 202122_s_at | -0.8439 | 0.0000 | |
| GSE26886 | PLIN3 | 10226 | 202122_s_at | -2.2349 | 0.0000 | |
| GSE29001 | PLIN3 | 10226 | 202122_s_at | -1.2255 | 0.0000 | |
| GSE38129 | PLIN3 | 10226 | 202122_s_at | -0.7059 | 0.0045 | |
| GSE45670 | PLIN3 | 10226 | 202122_s_at | 0.0692 | 0.7901 | |
| GSE53622 | PLIN3 | 10226 | 31883 | -0.8436 | 0.0000 | |
| GSE53624 | PLIN3 | 10226 | 31883 | -1.0390 | 0.0000 | |
| GSE63941 | PLIN3 | 10226 | 202122_s_at | -1.5884 | 0.0247 | |
| GSE77861 | PLIN3 | 10226 | 202122_s_at | -0.6810 | 0.0291 | |
| GSE97050 | PLIN3 | 10226 | A_23_P101707 | -0.1141 | 0.8643 | |
| SRP007169 | PLIN3 | 10226 | RNAseq | -3.2098 | 0.0000 | |
| SRP008496 | PLIN3 | 10226 | RNAseq | -2.8915 | 0.0000 | |
| SRP064894 | PLIN3 | 10226 | RNAseq | -1.3562 | 0.0000 | |
| SRP133303 | PLIN3 | 10226 | RNAseq | -0.9869 | 0.0000 | |
| SRP159526 | PLIN3 | 10226 | RNAseq | -2.2049 | 0.0000 | |
| SRP193095 | PLIN3 | 10226 | RNAseq | -1.5791 | 0.0000 | |
| SRP219564 | PLIN3 | 10226 | RNAseq | -1.6768 | 0.0010 | |
| TCGA | PLIN3 | 10226 | RNAseq | 0.1280 | 0.0604 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by PLIN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLIN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLIN3 | 10226 | 5 | 3 | 22 | |
| GSE20123 | PLIN3 | 10226 | 4 | 2 | 24 | |
| GSE43470 | PLIN3 | 10226 | 1 | 8 | 34 | |
| GSE46452 | PLIN3 | 10226 | 47 | 1 | 11 | |
| GSE47630 | PLIN3 | 10226 | 5 | 7 | 28 | |
| GSE54993 | PLIN3 | 10226 | 16 | 3 | 51 | |
| GSE54994 | PLIN3 | 10226 | 6 | 16 | 31 | |
| GSE60625 | PLIN3 | 10226 | 9 | 0 | 2 | |
| GSE74703 | PLIN3 | 10226 | 1 | 5 | 30 | |
| GSE74704 | PLIN3 | 10226 | 1 | 2 | 17 | |
| TCGA | PLIN3 | 10226 | 11 | 18 | 67 |
Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.
Somatic mutations of PLIN3:
Generating mutation plots.
Highly correlated genes for PLIN3:
Showing top 20/1376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLIN3 | TMEM40 | 0.823008 | 11 | 0 | 11 |
| PLIN3 | ELOVL1 | 0.811639 | 3 | 0 | 3 |
| PLIN3 | TGM1 | 0.810671 | 11 | 0 | 11 |
| PLIN3 | NUAK2 | 0.810572 | 3 | 0 | 3 |
| PLIN3 | SH3GL1 | 0.809568 | 11 | 0 | 11 |
| PLIN3 | EPGN | 0.809119 | 3 | 0 | 3 |
| PLIN3 | TMOD3 | 0.808582 | 11 | 0 | 11 |
| PLIN3 | NIPAL1 | 0.802624 | 3 | 0 | 3 |
| PLIN3 | MXD1 | 0.799845 | 11 | 0 | 11 |
| PLIN3 | ASCC2 | 0.789138 | 11 | 0 | 11 |
| PLIN3 | EPS8L1 | 0.788209 | 11 | 0 | 11 |
| PLIN3 | CWH43 | 0.785409 | 10 | 0 | 10 |
| PLIN3 | S100A16 | 0.781337 | 7 | 0 | 7 |
| PLIN3 | GALE | 0.780774 | 11 | 0 | 11 |
| PLIN3 | TP53I3 | 0.779215 | 12 | 0 | 12 |
| PLIN3 | LYPD3 | 0.777448 | 11 | 0 | 11 |
| PLIN3 | CRCT1 | 0.776648 | 11 | 0 | 10 |
| PLIN3 | CAPNS2 | 0.776223 | 4 | 0 | 4 |
| PLIN3 | CDA | 0.775845 | 11 | 0 | 11 |
| PLIN3 | EPHA2 | 0.772393 | 11 | 0 | 11 |
For details and further investigation, click here
