| Full name: polypeptide N-acetylgalactosaminyltransferase 3 | Alias Symbol: GalNAc-T3|HHS|HFTC | ||
| Type: protein-coding gene | Cytoband: 2q24.3 | ||
| Entrez ID: 2591 | HGNC ID: HGNC:4125 | Ensembl Gene: ENSG00000115339 | OMIM ID: 601756 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT3 | 2591 | 203397_s_at | 0.5335 | 0.5119 | |
| GSE20347 | GALNT3 | 2591 | 203397_s_at | -0.3787 | 0.0343 | |
| GSE23400 | GALNT3 | 2591 | 203397_s_at | -0.0549 | 0.7172 | |
| GSE26886 | GALNT3 | 2591 | 203397_s_at | -0.7190 | 0.0073 | |
| GSE29001 | GALNT3 | 2591 | 203397_s_at | -0.2460 | 0.5394 | |
| GSE38129 | GALNT3 | 2591 | 203397_s_at | 0.3388 | 0.4088 | |
| GSE45670 | GALNT3 | 2591 | 203397_s_at | 0.2082 | 0.3479 | |
| GSE53622 | GALNT3 | 2591 | 92287 | -0.1013 | 0.6977 | |
| GSE53624 | GALNT3 | 2591 | 92287 | -0.3758 | 0.0076 | |
| GSE63941 | GALNT3 | 2591 | 203397_s_at | 4.9921 | 0.0003 | |
| GSE77861 | GALNT3 | 2591 | 203397_s_at | -0.0981 | 0.7292 | |
| GSE97050 | GALNT3 | 2591 | A_24_P114249 | 0.1852 | 0.8278 | |
| SRP007169 | GALNT3 | 2591 | RNAseq | -0.6915 | 0.3161 | |
| SRP008496 | GALNT3 | 2591 | RNAseq | -0.7646 | 0.0418 | |
| SRP064894 | GALNT3 | 2591 | RNAseq | -0.5497 | 0.1758 | |
| SRP133303 | GALNT3 | 2591 | RNAseq | 0.0202 | 0.9302 | |
| SRP159526 | GALNT3 | 2591 | RNAseq | -0.5445 | 0.1176 | |
| SRP193095 | GALNT3 | 2591 | RNAseq | -0.9294 | 0.0000 | |
| SRP219564 | GALNT3 | 2591 | RNAseq | -1.1866 | 0.1681 | |
| TCGA | GALNT3 | 2591 | RNAseq | -0.0149 | 0.8990 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GALNT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT3 | 2591 | 5 | 1 | 24 | |
| GSE20123 | GALNT3 | 2591 | 4 | 1 | 25 | |
| GSE43470 | GALNT3 | 2591 | 5 | 1 | 37 | |
| GSE46452 | GALNT3 | 2591 | 1 | 4 | 54 | |
| GSE47630 | GALNT3 | 2591 | 5 | 3 | 32 | |
| GSE54993 | GALNT3 | 2591 | 0 | 5 | 65 | |
| GSE54994 | GALNT3 | 2591 | 11 | 2 | 40 | |
| GSE60625 | GALNT3 | 2591 | 0 | 3 | 8 | |
| GSE74703 | GALNT3 | 2591 | 4 | 1 | 31 | |
| GSE74704 | GALNT3 | 2591 | 2 | 0 | 18 | |
| TCGA | GALNT3 | 2591 | 25 | 9 | 62 |
Total number of gains: 62; Total number of losses: 30; Total Number of normals: 396.
Somatic mutations of GALNT3:
Generating mutation plots.
Highly correlated genes for GALNT3:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT3 | AP1S3 | 0.824969 | 4 | 0 | 4 |
| GALNT3 | IRX3 | 0.780355 | 3 | 0 | 3 |
| GALNT3 | SPINT2 | 0.758602 | 6 | 0 | 6 |
| GALNT3 | TMEM54 | 0.743376 | 4 | 0 | 3 |
| GALNT3 | KRT18 | 0.734189 | 3 | 0 | 3 |
| GALNT3 | CSF2RA | 0.733533 | 3 | 0 | 3 |
| GALNT3 | C1orf112 | 0.721673 | 3 | 0 | 3 |
| GALNT3 | RNF149 | 0.700728 | 4 | 0 | 3 |
| GALNT3 | ZNF710 | 0.695808 | 3 | 0 | 3 |
| GALNT3 | S1PR5 | 0.689213 | 4 | 0 | 3 |
| GALNT3 | TMEM30B | 0.681996 | 9 | 0 | 7 |
| GALNT3 | SORD | 0.6815 | 6 | 0 | 4 |
| GALNT3 | DICER1 | 0.67753 | 3 | 0 | 3 |
| GALNT3 | SNRNP200 | 0.677497 | 3 | 0 | 3 |
| GALNT3 | NIPAL1 | 0.676671 | 3 | 0 | 3 |
| GALNT3 | BCL11A | 0.670909 | 3 | 0 | 3 |
| GALNT3 | FAM83B | 0.669901 | 6 | 0 | 5 |
| GALNT3 | ITGA6 | 0.666518 | 3 | 0 | 3 |
| GALNT3 | ERAP2 | 0.665561 | 3 | 0 | 3 |
| GALNT3 | DIAPH1 | 0.664979 | 7 | 0 | 6 |
For details and further investigation, click here
