Full name: gigaxonin	Alias Symbol: GAN1|KLHL16
Type: protein-coding gene	Cytoband: 16q23.2
Entrez ID: 8139	HGNC ID: HGNC:4137	Ensembl Gene: ENSG00000261609	OMIM ID: 605379
Drug and gene relationship at DGIdb

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Expression of GAN:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	GAN	8139	228567_at	0.1849	0.6469	Show
GSE20347	GAN	8139	220124_at	-0.3668	0.0133	Show
GSE23400	GAN	8139	220124_at	-0.0515	0.1149	Show
GSE26886	GAN	8139	228567_at	-0.8157	0.0015	Show
GSE29001	GAN	8139	220124_at	-0.2931	0.4517	Show
GSE38129	GAN	8139	220124_at	-0.0482	0.8313	Show
GSE45670	GAN	8139	228567_at	-0.1303	0.5907	Show
GSE53622	GAN	8139	138116	-0.6034	0.0000	Show
GSE53624	GAN	8139	138116	-0.5477	0.0000	Show
GSE63941	GAN	8139	228567_at	0.3926	0.3847	Show
GSE77861	GAN	8139	228567_at	-0.1682	0.6971	Show
GSE97050	GAN	8139	A_23_P88873	-0.0310	0.9238	Show
SRP007169	GAN	8139	RNAseq	-0.2439	0.6681	Show
SRP008496	GAN	8139	RNAseq	-0.1472	0.6749	Show
SRP064894	GAN	8139	RNAseq	-1.2335	0.0018	Show
SRP133303	GAN	8139	RNAseq	-0.5463	0.0005	Show
SRP159526	GAN	8139	RNAseq	-0.0432	0.9367	Show
SRP193095	GAN	8139	RNAseq	-0.7881	0.0000	Show
SRP219564	GAN	8139	RNAseq	-1.0558	0.0822	Show
TCGA	GAN	8139	RNAseq	0.0295	0.8020	Show

Upregulated datasets: 0; Downregulated datasets: 1.  Download Data

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Survival by GAN expression:

 

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Copy number change of GAN:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	GAN	8139	5	3	22	Show
GSE20123	GAN	8139	5	3	22	Show
GSE43470	GAN	8139	2	8	33	Show
GSE46452	GAN	8139	37	2	20	Show
GSE47630	GAN	8139	11	9	20	Show
GSE54993	GAN	8139	2	4	64	Show
GSE54994	GAN	8139	7	10	36	Show
GSE60625	GAN	8139	4	0	7	Show
GSE74703	GAN	8139	2	6	28	Show
GSE74704	GAN	8139	3	2	15	Show
TCGA	GAN	8139	25	16	55	Show

Total number of gains: 103; Total number of losses: 63; Total Number of normals: 322.  Download Data

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Somatic mutations of GAN:

 

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Highly correlated genes for GAN:

 

Showing top 20/704 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
GAN	CPEB4	0.703905	3	0	3
GAN	PITHD1	0.685664	4	0	4
GAN	OSBPL8	0.684142	3	0	3
GAN	ELOVL1	0.683756	3	0	3
GAN	CAPNS2	0.668855	4	0	4
GAN	RAB8A	0.66422	3	0	3
GAN	NPC1	0.660019	3	0	3
GAN	STXBP5	0.65895	5	0	4
GAN	CTTNBP2NL	0.654402	4	0	4
GAN	METRNL	0.653765	4	0	4
GAN	SLC22A15	0.653311	3	0	3
GAN	PSMD5	0.652034	4	0	4
GAN	TAX1BP3	0.645157	3	0	3
GAN	GRPEL2	0.639921	4	0	3
GAN	NIP7	0.632761	5	0	5
GAN	JAG1	0.631733	4	0	3
GAN	HK1	0.628941	8	0	8
GAN	PPP2R2C	0.628282	4	0	4
GAN	GSDMC	0.626959	5	0	4
GAN	ABLIM2	0.623926	4	0	4

For details and further investigation, click here