| Full name: E2F transcription factor 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q21.2 | ||
| Entrez ID: 144455 | HGNC ID: HGNC:23820 | Ensembl Gene: ENSG00000165891 | OMIM ID: 612046 |
| Drug and gene relationship at DGIdb | |||
Expression of E2F7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | E2F7 | 144455 | 228033_at | 1.5869 | 0.1555 | |
| GSE26886 | E2F7 | 144455 | 228033_at | 0.6923 | 0.0506 | |
| GSE45670 | E2F7 | 144455 | 228033_at | 1.9120 | 0.0000 | |
| GSE53622 | E2F7 | 144455 | 46411 | 1.2375 | 0.0000 | |
| GSE53624 | E2F7 | 144455 | 46411 | 1.5050 | 0.0000 | |
| GSE63941 | E2F7 | 144455 | 228033_at | 1.9147 | 0.0124 | |
| GSE77861 | E2F7 | 144455 | 241725_at | -0.0285 | 0.8349 | |
| GSE97050 | E2F7 | 144455 | A_32_P210202 | 1.0190 | 0.1675 | |
| SRP007169 | E2F7 | 144455 | RNAseq | 4.2971 | 0.0000 | |
| SRP008496 | E2F7 | 144455 | RNAseq | 3.7328 | 0.0000 | |
| SRP133303 | E2F7 | 144455 | RNAseq | 2.0449 | 0.0000 | |
| SRP159526 | E2F7 | 144455 | RNAseq | 1.6662 | 0.0000 | |
| SRP193095 | E2F7 | 144455 | RNAseq | 1.2306 | 0.0000 | |
| SRP219564 | E2F7 | 144455 | RNAseq | 1.1706 | 0.1898 | |
| TCGA | E2F7 | 144455 | RNAseq | 1.5434 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by E2F7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of E2F7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | E2F7 | 144455 | 3 | 3 | 24 | |
| GSE20123 | E2F7 | 144455 | 3 | 3 | 24 | |
| GSE43470 | E2F7 | 144455 | 3 | 1 | 39 | |
| GSE46452 | E2F7 | 144455 | 8 | 1 | 50 | |
| GSE47630 | E2F7 | 144455 | 10 | 1 | 29 | |
| GSE54993 | E2F7 | 144455 | 0 | 5 | 65 | |
| GSE54994 | E2F7 | 144455 | 6 | 1 | 46 | |
| GSE60625 | E2F7 | 144455 | 0 | 0 | 11 | |
| GSE74703 | E2F7 | 144455 | 3 | 1 | 32 | |
| GSE74704 | E2F7 | 144455 | 2 | 2 | 16 | |
| TCGA | E2F7 | 144455 | 14 | 15 | 67 |
Total number of gains: 52; Total number of losses: 33; Total Number of normals: 403.
Somatic mutations of E2F7:
Generating mutation plots.
Highly correlated genes for E2F7:
Showing top 20/1009 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| E2F7 | NCAPH | 0.811331 | 4 | 0 | 4 |
| E2F7 | CDC45 | 0.807835 | 7 | 0 | 7 |
| E2F7 | KIF2C | 0.80063 | 7 | 0 | 7 |
| E2F7 | HJURP | 0.797965 | 6 | 0 | 6 |
| E2F7 | KIF18B | 0.797378 | 6 | 0 | 6 |
| E2F7 | CDC20 | 0.787398 | 7 | 0 | 7 |
| E2F7 | C1orf112 | 0.786466 | 3 | 0 | 3 |
| E2F7 | STIL | 0.782432 | 7 | 0 | 7 |
| E2F7 | CDK1 | 0.773673 | 7 | 0 | 7 |
| E2F7 | SLC20A1 | 0.772329 | 3 | 0 | 3 |
| E2F7 | MTFR2 | 0.771691 | 6 | 0 | 6 |
| E2F7 | DLGAP5 | 0.771034 | 8 | 0 | 7 |
| E2F7 | CDCA8 | 0.768255 | 7 | 0 | 7 |
| E2F7 | PFDN2 | 0.765887 | 3 | 0 | 3 |
| E2F7 | UHRF1 | 0.764444 | 8 | 0 | 8 |
| E2F7 | MCM2 | 0.762683 | 8 | 0 | 8 |
| E2F7 | CDCA5 | 0.757065 | 7 | 0 | 7 |
| E2F7 | TRIP13 | 0.756322 | 7 | 0 | 7 |
| E2F7 | RACGAP1 | 0.754328 | 5 | 0 | 4 |
| E2F7 | CCNB2 | 0.752345 | 6 | 0 | 5 |
For details and further investigation, click here
