| Full name: potassium voltage-gated channel modifier subfamily S member 3 | Alias Symbol: Kv9.3 | ||
| Type: protein-coding gene | Cytoband: 2p24.2 | ||
| Entrez ID: 3790 | HGNC ID: HGNC:6302 | Ensembl Gene: ENSG00000170745 | OMIM ID: 603888 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNS3 | 3790 | 205968_at | 1.7376 | 0.0331 | |
| GSE20347 | KCNS3 | 3790 | 205968_at | 2.0179 | 0.0000 | |
| GSE23400 | KCNS3 | 3790 | 205968_at | 0.8154 | 0.0000 | |
| GSE26886 | KCNS3 | 3790 | 205968_at | 1.6254 | 0.0007 | |
| GSE29001 | KCNS3 | 3790 | 205968_at | 1.3246 | 0.0031 | |
| GSE38129 | KCNS3 | 3790 | 205968_at | 1.6693 | 0.0000 | |
| GSE45670 | KCNS3 | 3790 | 205968_at | 1.4239 | 0.0052 | |
| GSE53622 | KCNS3 | 3790 | 89701 | 1.2758 | 0.0000 | |
| GSE53624 | KCNS3 | 3790 | 89701 | 1.5494 | 0.0000 | |
| GSE63941 | KCNS3 | 3790 | 205968_at | 0.2452 | 0.8755 | |
| GSE77861 | KCNS3 | 3790 | 205968_at | 1.8100 | 0.0045 | |
| GSE97050 | KCNS3 | 3790 | A_23_P120103 | 0.7470 | 0.3458 | |
| SRP007169 | KCNS3 | 3790 | RNAseq | 3.4675 | 0.0000 | |
| SRP008496 | KCNS3 | 3790 | RNAseq | 3.3836 | 0.0000 | |
| SRP064894 | KCNS3 | 3790 | RNAseq | 1.6781 | 0.0000 | |
| SRP133303 | KCNS3 | 3790 | RNAseq | 1.8110 | 0.0000 | |
| SRP159526 | KCNS3 | 3790 | RNAseq | 2.4949 | 0.0000 | |
| SRP193095 | KCNS3 | 3790 | RNAseq | 1.6694 | 0.0000 | |
| SRP219564 | KCNS3 | 3790 | RNAseq | 1.6319 | 0.0003 | |
| TCGA | KCNS3 | 3790 | RNAseq | 0.6705 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by KCNS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNS3 | 3790 | 10 | 2 | 18 | |
| GSE20123 | KCNS3 | 3790 | 10 | 2 | 18 | |
| GSE43470 | KCNS3 | 3790 | 2 | 0 | 41 | |
| GSE46452 | KCNS3 | 3790 | 3 | 4 | 52 | |
| GSE47630 | KCNS3 | 3790 | 7 | 0 | 33 | |
| GSE54993 | KCNS3 | 3790 | 0 | 7 | 63 | |
| GSE54994 | KCNS3 | 3790 | 10 | 0 | 43 | |
| GSE60625 | KCNS3 | 3790 | 0 | 3 | 8 | |
| GSE74703 | KCNS3 | 3790 | 2 | 0 | 34 | |
| GSE74704 | KCNS3 | 3790 | 9 | 2 | 9 | |
| TCGA | KCNS3 | 3790 | 36 | 3 | 57 |
Total number of gains: 89; Total number of losses: 23; Total Number of normals: 376.
Somatic mutations of KCNS3:
Generating mutation plots.
Highly correlated genes for KCNS3:
Showing top 20/1624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNS3 | FAM89B | 0.782275 | 3 | 0 | 3 |
| KCNS3 | HAS3 | 0.76088 | 4 | 0 | 4 |
| KCNS3 | GHDC | 0.760729 | 3 | 0 | 3 |
| KCNS3 | PYCR2 | 0.728174 | 3 | 0 | 3 |
| KCNS3 | FADS1 | 0.722302 | 3 | 0 | 3 |
| KCNS3 | SGTB | 0.721249 | 3 | 0 | 3 |
| KCNS3 | ZC3H18 | 0.716134 | 4 | 0 | 4 |
| KCNS3 | TRAF7 | 0.714846 | 4 | 0 | 4 |
| KCNS3 | CDCA2 | 0.711251 | 5 | 0 | 5 |
| KCNS3 | CDK6 | 0.710753 | 5 | 0 | 5 |
| KCNS3 | TMTC1 | 0.710456 | 4 | 0 | 3 |
| KCNS3 | CERS5 | 0.706369 | 5 | 0 | 4 |
| KCNS3 | KNSTRN | 0.704898 | 6 | 0 | 6 |
| KCNS3 | C1orf131 | 0.701877 | 7 | 0 | 7 |
| KCNS3 | MFHAS1 | 0.701817 | 11 | 0 | 11 |
| KCNS3 | SIX4 | 0.701749 | 8 | 0 | 7 |
| KCNS3 | M6PR | 0.701682 | 4 | 0 | 4 |
| KCNS3 | PIGX | 0.70166 | 7 | 0 | 7 |
| KCNS3 | STK17A | 0.699682 | 3 | 0 | 3 |
| KCNS3 | ASXL2 | 0.699328 | 5 | 0 | 4 |
For details and further investigation, click here
