| Full name: glycoprotein V platelet | Alias Symbol: CD42d | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 2814 | HGNC ID: HGNC:4443 | Ensembl Gene: ENSG00000178732 | OMIM ID: 173511 |
| Drug and gene relationship at DGIdb | |||
GP5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04611 | Platelet activation |
Expression of GP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GP5 | 2814 | 207926_at | 0.0978 | 0.5906 | |
| GSE20347 | GP5 | 2814 | 207926_at | 0.0982 | 0.1235 | |
| GSE23400 | GP5 | 2814 | 207926_at | 0.0316 | 0.2520 | |
| GSE26886 | GP5 | 2814 | 207926_at | -0.0273 | 0.8233 | |
| GSE29001 | GP5 | 2814 | 207926_at | 0.0332 | 0.8775 | |
| GSE38129 | GP5 | 2814 | 207926_at | 0.0572 | 0.5543 | |
| GSE45670 | GP5 | 2814 | 207926_at | 0.1520 | 0.1104 | |
| GSE53622 | GP5 | 2814 | 49661 | 0.3550 | 0.0085 | |
| GSE53624 | GP5 | 2814 | 49661 | 0.1236 | 0.3601 | |
| GSE63941 | GP5 | 2814 | 207926_at | -0.2253 | 0.0636 | |
| GSE77861 | GP5 | 2814 | 207926_at | 0.0474 | 0.5834 | |
| TCGA | GP5 | 2814 | RNAseq | 0.3374 | 0.4818 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GP5 | 2814 | 22 | 0 | 8 | |
| GSE20123 | GP5 | 2814 | 22 | 0 | 8 | |
| GSE43470 | GP5 | 2814 | 24 | 0 | 19 | |
| GSE46452 | GP5 | 2814 | 19 | 1 | 39 | |
| GSE47630 | GP5 | 2814 | 27 | 2 | 11 | |
| GSE54993 | GP5 | 2814 | 1 | 21 | 48 | |
| GSE54994 | GP5 | 2814 | 41 | 0 | 12 | |
| GSE60625 | GP5 | 2814 | 0 | 6 | 5 | |
| GSE74703 | GP5 | 2814 | 20 | 0 | 16 | |
| GSE74704 | GP5 | 2814 | 14 | 0 | 6 | |
| TCGA | GP5 | 2814 | 77 | 0 | 19 |
Total number of gains: 267; Total number of losses: 30; Total Number of normals: 191.
Somatic mutations of GP5:
Generating mutation plots.
Highly correlated genes for GP5:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GP5 | TFAP4 | 0.693719 | 3 | 0 | 3 |
| GP5 | RHAG | 0.653773 | 3 | 0 | 3 |
| GP5 | SLIT1 | 0.63467 | 3 | 0 | 3 |
| GP5 | FN3K | 0.627785 | 3 | 0 | 3 |
| GP5 | DPF3 | 0.626753 | 4 | 0 | 3 |
| GP5 | PROX1 | 0.615457 | 4 | 0 | 3 |
| GP5 | HCRTR1 | 0.613798 | 3 | 0 | 3 |
| GP5 | CGA | 0.610474 | 3 | 0 | 3 |
| GP5 | KATNB1 | 0.606746 | 3 | 0 | 3 |
| GP5 | SLC10A1 | 0.605757 | 3 | 0 | 3 |
| GP5 | RPS6KA6 | 0.603851 | 4 | 0 | 3 |
| GP5 | COLEC10 | 0.602725 | 4 | 0 | 4 |
| GP5 | NOVA2 | 0.597804 | 4 | 0 | 3 |
| GP5 | LGI2 | 0.594105 | 4 | 0 | 3 |
| GP5 | PTGER3 | 0.590228 | 3 | 0 | 3 |
| GP5 | MAP1A | 0.587452 | 4 | 0 | 3 |
| GP5 | PRORY | 0.587054 | 3 | 0 | 3 |
| GP5 | ARVCF | 0.585404 | 4 | 0 | 4 |
| GP5 | ZKSCAN3 | 0.582066 | 3 | 0 | 3 |
| GP5 | FBXL18 | 0.582062 | 3 | 0 | 3 |
For details and further investigation, click here
