| Full name: G protein-coupled receptor 137B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.3 | ||
| Entrez ID: 7107 | HGNC ID: HGNC:11862 | Ensembl Gene: ENSG00000077585 | OMIM ID: 604658 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR137B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR137B | 7107 | 204137_at | 0.8842 | 0.1075 | |
| GSE20347 | GPR137B | 7107 | 204137_at | 0.8947 | 0.0000 | |
| GSE23400 | GPR137B | 7107 | 204137_at | 0.9098 | 0.0000 | |
| GSE26886 | GPR137B | 7107 | 204137_at | 0.9585 | 0.0069 | |
| GSE29001 | GPR137B | 7107 | 204137_at | 1.2015 | 0.0185 | |
| GSE38129 | GPR137B | 7107 | 204137_at | 1.0854 | 0.0000 | |
| GSE45670 | GPR137B | 7107 | 204137_at | 0.6220 | 0.0062 | |
| GSE53622 | GPR137B | 7107 | 86624 | 0.9939 | 0.0000 | |
| GSE53624 | GPR137B | 7107 | 80 | 0.9404 | 0.0000 | |
| GSE63941 | GPR137B | 7107 | 204137_at | -2.2346 | 0.0015 | |
| GSE77861 | GPR137B | 7107 | 204137_at | 0.9600 | 0.1151 | |
| GSE97050 | GPR137B | 7107 | A_33_P3243618 | 0.6581 | 0.1383 | |
| SRP007169 | GPR137B | 7107 | RNAseq | 1.7437 | 0.0081 | |
| SRP008496 | GPR137B | 7107 | RNAseq | 1.4957 | 0.0012 | |
| SRP064894 | GPR137B | 7107 | RNAseq | 1.2627 | 0.0000 | |
| SRP133303 | GPR137B | 7107 | RNAseq | 1.2193 | 0.0000 | |
| SRP159526 | GPR137B | 7107 | RNAseq | 0.8057 | 0.0685 | |
| SRP193095 | GPR137B | 7107 | RNAseq | 0.4615 | 0.0004 | |
| SRP219564 | GPR137B | 7107 | RNAseq | 0.6901 | 0.0676 | |
| TCGA | GPR137B | 7107 | RNAseq | 0.2840 | 0.0001 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by GPR137B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR137B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR137B | 7107 | 10 | 1 | 19 | |
| GSE20123 | GPR137B | 7107 | 11 | 1 | 18 | |
| GSE43470 | GPR137B | 7107 | 9 | 1 | 33 | |
| GSE46452 | GPR137B | 7107 | 4 | 2 | 53 | |
| GSE47630 | GPR137B | 7107 | 15 | 0 | 25 | |
| GSE54993 | GPR137B | 7107 | 0 | 6 | 64 | |
| GSE54994 | GPR137B | 7107 | 16 | 0 | 37 | |
| GSE60625 | GPR137B | 7107 | 0 | 0 | 11 | |
| GSE74703 | GPR137B | 7107 | 9 | 1 | 26 | |
| GSE74704 | GPR137B | 7107 | 5 | 0 | 15 | |
| TCGA | GPR137B | 7107 | 43 | 4 | 49 |
Total number of gains: 122; Total number of losses: 16; Total Number of normals: 350.
Somatic mutations of GPR137B:
Generating mutation plots.
Highly correlated genes for GPR137B:
Showing top 20/1343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR137B | CEP170 | 0.78713 | 3 | 0 | 3 |
| GPR137B | PYCR2 | 0.764363 | 3 | 0 | 3 |
| GPR137B | PREX1 | 0.755064 | 3 | 0 | 3 |
| GPR137B | GNG10 | 0.752403 | 3 | 0 | 3 |
| GPR137B | FCGR3A | 0.727839 | 3 | 0 | 3 |
| GPR137B | LRRC8C | 0.719751 | 3 | 0 | 3 |
| GPR137B | GPR107 | 0.718734 | 4 | 0 | 4 |
| GPR137B | RAB34 | 0.718376 | 3 | 0 | 3 |
| GPR137B | GXYLT2 | 0.717401 | 5 | 0 | 5 |
| GPR137B | USF1 | 0.716242 | 4 | 0 | 4 |
| GPR137B | NF1 | 0.715644 | 3 | 0 | 3 |
| GPR137B | SNAP47 | 0.714804 | 3 | 0 | 3 |
| GPR137B | PDIA5 | 0.714219 | 3 | 0 | 3 |
| GPR137B | SH2B2 | 0.714136 | 3 | 0 | 3 |
| GPR137B | TRPC4AP | 0.712174 | 3 | 0 | 3 |
| GPR137B | PBXIP1 | 0.70515 | 4 | 0 | 4 |
| GPR137B | SLC35B3 | 0.704827 | 4 | 0 | 4 |
| GPR137B | SPON2 | 0.702841 | 3 | 0 | 3 |
| GPR137B | MINPP1 | 0.701022 | 12 | 0 | 12 |
| GPR137B | ACVR1 | 0.698082 | 11 | 0 | 10 |
For details and further investigation, click here
