| Full name: growth regulating estrogen receptor binding 1 | Alias Symbol: KIAA0575 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 9687 | HGNC ID: HGNC:24885 | Ensembl Gene: ENSG00000196208 | OMIM ID: 611736 |
| Drug and gene relationship at DGIdb | |||
Expression of GREB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GREB1 | 9687 | 210855_at | 0.2858 | 0.3264 | |
| GSE20347 | GREB1 | 9687 | 210855_at | 0.0980 | 0.1864 | |
| GSE23400 | GREB1 | 9687 | 210855_at | -0.0129 | 0.5174 | |
| GSE26886 | GREB1 | 9687 | 210855_at | -0.1979 | 0.0791 | |
| GSE29001 | GREB1 | 9687 | 210562_at | 0.0489 | 0.6645 | |
| GSE38129 | GREB1 | 9687 | 210855_at | 0.0239 | 0.7763 | |
| GSE45670 | GREB1 | 9687 | 210855_at | -0.0489 | 0.5965 | |
| GSE53622 | GREB1 | 9687 | 79418 | 0.1681 | 0.0610 | |
| GSE53624 | GREB1 | 9687 | 79418 | 0.2693 | 0.0178 | |
| GSE63941 | GREB1 | 9687 | 210855_at | 0.4173 | 0.0072 | |
| GSE77861 | GREB1 | 9687 | 210855_at | 0.0560 | 0.5953 | |
| GSE97050 | GREB1 | 9687 | A_23_P412476 | -0.0746 | 0.8010 | |
| SRP007169 | GREB1 | 9687 | RNAseq | 2.1047 | 0.0425 | |
| SRP064894 | GREB1 | 9687 | RNAseq | 0.6499 | 0.0444 | |
| SRP133303 | GREB1 | 9687 | RNAseq | 0.5361 | 0.0103 | |
| SRP159526 | GREB1 | 9687 | RNAseq | 0.6404 | 0.2012 | |
| SRP193095 | GREB1 | 9687 | RNAseq | 0.3349 | 0.0483 | |
| SRP219564 | GREB1 | 9687 | RNAseq | 2.3587 | 0.0033 | |
| TCGA | GREB1 | 9687 | RNAseq | -0.6083 | 0.0061 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by GREB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GREB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GREB1 | 9687 | 10 | 2 | 18 | |
| GSE20123 | GREB1 | 9687 | 10 | 2 | 18 | |
| GSE43470 | GREB1 | 9687 | 2 | 1 | 40 | |
| GSE46452 | GREB1 | 9687 | 3 | 4 | 52 | |
| GSE47630 | GREB1 | 9687 | 7 | 0 | 33 | |
| GSE54993 | GREB1 | 9687 | 0 | 7 | 63 | |
| GSE54994 | GREB1 | 9687 | 11 | 0 | 42 | |
| GSE60625 | GREB1 | 9687 | 0 | 3 | 8 | |
| GSE74703 | GREB1 | 9687 | 2 | 0 | 34 | |
| GSE74704 | GREB1 | 9687 | 9 | 1 | 10 | |
| TCGA | GREB1 | 9687 | 34 | 5 | 57 |
Total number of gains: 88; Total number of losses: 25; Total Number of normals: 375.
Somatic mutations of GREB1:
Generating mutation plots.
Highly correlated genes for GREB1:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GREB1 | RENBP | 0.760298 | 4 | 0 | 4 |
| GREB1 | ORM1 | 0.757939 | 4 | 0 | 4 |
| GREB1 | GPHA2 | 0.727648 | 3 | 0 | 3 |
| GREB1 | RLN3 | 0.689513 | 3 | 0 | 3 |
| GREB1 | FGF22 | 0.683114 | 6 | 0 | 6 |
| GREB1 | CDRT15 | 0.675568 | 3 | 0 | 3 |
| GREB1 | AGAP2 | 0.673786 | 4 | 0 | 3 |
| GREB1 | TMEM221 | 0.66599 | 3 | 0 | 3 |
| GREB1 | DNMT3L | 0.665361 | 3 | 0 | 3 |
| GREB1 | TNFSF11 | 0.664888 | 3 | 0 | 3 |
| GREB1 | KCNJ11 | 0.661641 | 3 | 0 | 3 |
| GREB1 | CHIT1 | 0.661265 | 4 | 0 | 3 |
| GREB1 | ZNRF4 | 0.655706 | 5 | 0 | 4 |
| GREB1 | RHBDL1 | 0.653276 | 4 | 0 | 4 |
| GREB1 | SEMA3B | 0.652842 | 3 | 0 | 3 |
| GREB1 | HDAC8 | 0.651953 | 3 | 0 | 3 |
| GREB1 | MEPE | 0.648941 | 5 | 0 | 4 |
| GREB1 | KIF21B | 0.648869 | 7 | 0 | 6 |
| GREB1 | CCDC157 | 0.646499 | 3 | 0 | 3 |
| GREB1 | DCDC1 | 0.645178 | 3 | 0 | 3 |
For details and further investigation, click here
