| Full name: membrane palmitoylated protein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 58538 | HGNC ID: HGNC:13680 | Ensembl Gene: ENSG00000082126 | OMIM ID: 606575 |
| Drug and gene relationship at DGIdb | |||
Expression of MPP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPP4 | 58538 | 1555099_at | -0.0221 | 0.9345 | |
| GSE26886 | MPP4 | 58538 | 1555099_at | -0.0240 | 0.8340 | |
| GSE45670 | MPP4 | 58538 | 1552489_s_at | 0.6173 | 0.1439 | |
| GSE53622 | MPP4 | 58538 | 16787 | 1.1869 | 0.0000 | |
| GSE53624 | MPP4 | 58538 | 16787 | 2.4233 | 0.0000 | |
| GSE63941 | MPP4 | 58538 | 1555099_at | -0.0477 | 0.7553 | |
| GSE77861 | MPP4 | 58538 | 1555099_at | 0.0429 | 0.6558 | |
| GSE97050 | MPP4 | 58538 | A_23_P131263 | -0.2305 | 0.4166 | |
| TCGA | MPP4 | 58538 | RNAseq | 3.1124 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MPP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPP4 | 58538 | 6 | 4 | 20 | |
| GSE20123 | MPP4 | 58538 | 6 | 4 | 20 | |
| GSE43470 | MPP4 | 58538 | 1 | 1 | 41 | |
| GSE46452 | MPP4 | 58538 | 1 | 4 | 54 | |
| GSE47630 | MPP4 | 58538 | 4 | 5 | 31 | |
| GSE54993 | MPP4 | 58538 | 0 | 3 | 67 | |
| GSE54994 | MPP4 | 58538 | 10 | 8 | 35 | |
| GSE60625 | MPP4 | 58538 | 0 | 3 | 8 | |
| GSE74703 | MPP4 | 58538 | 1 | 1 | 34 | |
| GSE74704 | MPP4 | 58538 | 3 | 2 | 15 | |
| TCGA | MPP4 | 58538 | 21 | 11 | 64 |
Total number of gains: 53; Total number of losses: 46; Total Number of normals: 389.
Somatic mutations of MPP4:
Generating mutation plots.
Highly correlated genes for MPP4:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPP4 | MAPK10 | 0.669652 | 3 | 0 | 3 |
| MPP4 | FOXC1 | 0.609909 | 3 | 0 | 3 |
| MPP4 | CIB1 | 0.601206 | 3 | 0 | 3 |
| MPP4 | PSMB3 | 0.596335 | 3 | 0 | 3 |
| MPP4 | SLC7A11 | 0.586308 | 3 | 0 | 3 |
| MPP4 | SURF1 | 0.585223 | 3 | 0 | 3 |
| MPP4 | AGPS | 0.585222 | 4 | 0 | 4 |
| MPP4 | PRR5L | 0.579503 | 3 | 0 | 3 |
| MPP4 | IL31RA | 0.574815 | 3 | 0 | 3 |
| MPP4 | KLHL24 | 0.569221 | 3 | 0 | 3 |
| MPP4 | MED12L | 0.567887 | 3 | 0 | 3 |
| MPP4 | GLI2 | 0.566057 | 4 | 0 | 3 |
| MPP4 | GSTM4 | 0.565575 | 3 | 0 | 3 |
| MPP4 | SLC3A2 | 0.565102 | 3 | 0 | 3 |
| MPP4 | COL11A2 | 0.563156 | 3 | 0 | 3 |
| MPP4 | THEM4 | 0.559955 | 3 | 0 | 3 |
| MPP4 | CCDC65 | 0.558517 | 3 | 0 | 3 |
| MPP4 | FANCE | 0.556382 | 4 | 0 | 3 |
| MPP4 | UAP1L1 | 0.54812 | 4 | 0 | 3 |
| MPP4 | MAPK12 | 0.546549 | 4 | 0 | 3 |
For details and further investigation, click here
