| Full name: general transcription factor IIF subunit 2 | Alias Symbol: TFIIF|BTF4|RAP30 | ||
| Type: protein-coding gene | Cytoband: 13q14.12-q14.13 | ||
| Entrez ID: 2963 | HGNC ID: HGNC:4653 | Ensembl Gene: ENSG00000188342 | OMIM ID: 189969 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GTF2F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2F2 | 2963 | 209595_at | 0.2360 | 0.5413 | |
| GSE20347 | GTF2F2 | 2963 | 209595_at | -0.0129 | 0.9312 | |
| GSE23400 | GTF2F2 | 2963 | 209595_at | 0.0624 | 0.0131 | |
| GSE26886 | GTF2F2 | 2963 | 209595_at | 0.6633 | 0.0076 | |
| GSE29001 | GTF2F2 | 2963 | 209595_at | 0.0413 | 0.7862 | |
| GSE38129 | GTF2F2 | 2963 | 209595_at | 0.1702 | 0.0612 | |
| GSE45670 | GTF2F2 | 2963 | 209595_at | 0.2066 | 0.2611 | |
| GSE53622 | GTF2F2 | 2963 | 11774 | 0.1269 | 0.0717 | |
| GSE53624 | GTF2F2 | 2963 | 11774 | 0.3058 | 0.0000 | |
| GSE63941 | GTF2F2 | 2963 | 209595_at | 0.2631 | 0.6815 | |
| GSE77861 | GTF2F2 | 2963 | 209595_at | 0.0797 | 0.6074 | |
| GSE97050 | GTF2F2 | 2963 | A_33_P3317198 | 0.5588 | 0.3638 | |
| SRP007169 | GTF2F2 | 2963 | RNAseq | -0.4428 | 0.2538 | |
| SRP008496 | GTF2F2 | 2963 | RNAseq | 0.2087 | 0.5731 | |
| SRP064894 | GTF2F2 | 2963 | RNAseq | 0.2185 | 0.1695 | |
| SRP133303 | GTF2F2 | 2963 | RNAseq | 0.0767 | 0.5764 | |
| SRP159526 | GTF2F2 | 2963 | RNAseq | -0.2484 | 0.2223 | |
| SRP193095 | GTF2F2 | 2963 | RNAseq | -0.0850 | 0.5260 | |
| SRP219564 | GTF2F2 | 2963 | RNAseq | -0.0880 | 0.7699 | |
| TCGA | GTF2F2 | 2963 | RNAseq | 0.2596 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2F2 | 2963 | 0 | 13 | 17 | |
| GSE20123 | GTF2F2 | 2963 | 0 | 12 | 18 | |
| GSE43470 | GTF2F2 | 2963 | 3 | 13 | 27 | |
| GSE46452 | GTF2F2 | 2963 | 0 | 33 | 26 | |
| GSE47630 | GTF2F2 | 2963 | 2 | 27 | 11 | |
| GSE54993 | GTF2F2 | 2963 | 12 | 2 | 56 | |
| GSE54994 | GTF2F2 | 2963 | 1 | 16 | 36 | |
| GSE60625 | GTF2F2 | 2963 | 0 | 3 | 8 | |
| GSE74703 | GTF2F2 | 2963 | 3 | 10 | 23 | |
| GSE74704 | GTF2F2 | 2963 | 0 | 9 | 11 | |
| TCGA | GTF2F2 | 2963 | 8 | 39 | 49 |
Total number of gains: 29; Total number of losses: 177; Total Number of normals: 282.
Somatic mutations of GTF2F2:
Generating mutation plots.
Highly correlated genes for GTF2F2:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2F2 | EXOC8 | 0.738618 | 3 | 0 | 3 |
| GTF2F2 | SLC22A5 | 0.727754 | 3 | 0 | 3 |
| GTF2F2 | MRPL52 | 0.725447 | 3 | 0 | 3 |
| GTF2F2 | RAD17 | 0.717568 | 3 | 0 | 3 |
| GTF2F2 | FADD | 0.715737 | 3 | 0 | 3 |
| GTF2F2 | PPP1R16A | 0.703547 | 3 | 0 | 3 |
| GTF2F2 | MSTO1 | 0.694862 | 3 | 0 | 3 |
| GTF2F2 | LRRC47 | 0.693863 | 3 | 0 | 3 |
| GTF2F2 | ALKBH3 | 0.68748 | 3 | 0 | 3 |
| GTF2F2 | GUSB | 0.687351 | 3 | 0 | 3 |
| GTF2F2 | DYNC2LI1 | 0.686522 | 3 | 0 | 3 |
| GTF2F2 | XXYLT1 | 0.683802 | 3 | 0 | 3 |
| GTF2F2 | ZNF146 | 0.672133 | 4 | 0 | 4 |
| GTF2F2 | DPP9 | 0.67184 | 3 | 0 | 3 |
| GTF2F2 | HSD17B7 | 0.671318 | 3 | 0 | 3 |
| GTF2F2 | MRPS9 | 0.671014 | 4 | 0 | 3 |
| GTF2F2 | SGTB | 0.67006 | 3 | 0 | 3 |
| GTF2F2 | DNMT3A | 0.664739 | 3 | 0 | 3 |
| GTF2F2 | PPIG | 0.661956 | 3 | 0 | 3 |
| GTF2F2 | FKTN | 0.659972 | 3 | 0 | 3 |
For details and further investigation, click here
