| Full name: ETS variant transcription factor 3 | Alias Symbol: PE-1 | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 2117 | HGNC ID: HGNC:3492 | Ensembl Gene: ENSG00000117036 | OMIM ID: 164873 |
| Drug and gene relationship at DGIdb | |||
Expression of ETV3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV3 | 2117 | 227200_at | 0.5511 | 0.1411 | |
| GSE20347 | ETV3 | 2117 | 214480_at | -0.0165 | 0.8603 | |
| GSE23400 | ETV3 | 2117 | 214480_at | -0.0278 | 0.4046 | |
| GSE26886 | ETV3 | 2117 | 227200_at | 0.2282 | 0.3139 | |
| GSE29001 | ETV3 | 2117 | 214480_at | -0.0678 | 0.6145 | |
| GSE38129 | ETV3 | 2117 | 214480_at | -0.0467 | 0.4976 | |
| GSE45670 | ETV3 | 2117 | 227200_at | 0.2282 | 0.0517 | |
| GSE53622 | ETV3 | 2117 | 138124 | 0.1222 | 0.0461 | |
| GSE53624 | ETV3 | 2117 | 63831 | 0.0888 | 0.3544 | |
| GSE63941 | ETV3 | 2117 | 227200_at | 0.4708 | 0.2120 | |
| GSE77861 | ETV3 | 2117 | 227200_at | 0.2884 | 0.2657 | |
| GSE97050 | ETV3 | 2117 | A_33_P3324860 | -0.1089 | 0.6631 | |
| SRP007169 | ETV3 | 2117 | RNAseq | -0.5129 | 0.1917 | |
| SRP008496 | ETV3 | 2117 | RNAseq | -0.1784 | 0.4903 | |
| SRP064894 | ETV3 | 2117 | RNAseq | -0.5981 | 0.0226 | |
| SRP133303 | ETV3 | 2117 | RNAseq | -0.0445 | 0.6494 | |
| SRP159526 | ETV3 | 2117 | RNAseq | 0.1913 | 0.5825 | |
| SRP193095 | ETV3 | 2117 | RNAseq | -0.1747 | 0.1192 | |
| SRP219564 | ETV3 | 2117 | RNAseq | -0.3881 | 0.4041 | |
| TCGA | ETV3 | 2117 | RNAseq | 0.0209 | 0.7950 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ETV3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV3 | 2117 | 12 | 0 | 18 | |
| GSE20123 | ETV3 | 2117 | 12 | 0 | 18 | |
| GSE43470 | ETV3 | 2117 | 7 | 2 | 34 | |
| GSE46452 | ETV3 | 2117 | 2 | 1 | 56 | |
| GSE47630 | ETV3 | 2117 | 14 | 0 | 26 | |
| GSE54993 | ETV3 | 2117 | 0 | 5 | 65 | |
| GSE54994 | ETV3 | 2117 | 16 | 0 | 37 | |
| GSE60625 | ETV3 | 2117 | 0 | 0 | 11 | |
| GSE74703 | ETV3 | 2117 | 7 | 2 | 27 | |
| GSE74704 | ETV3 | 2117 | 6 | 0 | 14 | |
| TCGA | ETV3 | 2117 | 38 | 2 | 56 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of ETV3:
Generating mutation plots.
Highly correlated genes for ETV3:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV3 | LRR1 | 0.8403 | 3 | 0 | 3 |
| ETV3 | PCSK9 | 0.779473 | 3 | 0 | 3 |
| ETV3 | CDCA5 | 0.773797 | 3 | 0 | 3 |
| ETV3 | RAD51 | 0.764864 | 3 | 0 | 3 |
| ETV3 | RAD54B | 0.762973 | 3 | 0 | 3 |
| ETV3 | BCL2L12 | 0.760127 | 3 | 0 | 3 |
| ETV3 | GTF2IRD2 | 0.755445 | 3 | 0 | 3 |
| ETV3 | SNAI2 | 0.743187 | 3 | 0 | 3 |
| ETV3 | CDC6 | 0.728561 | 4 | 0 | 4 |
| ETV3 | FAM189B | 0.727026 | 4 | 0 | 4 |
| ETV3 | DNMT3B | 0.705696 | 3 | 0 | 3 |
| ETV3 | LAMTOR2 | 0.70442 | 3 | 0 | 3 |
| ETV3 | ZNF264 | 0.702598 | 3 | 0 | 3 |
| ETV3 | HOXA11 | 0.702121 | 4 | 0 | 3 |
| ETV3 | ALKBH2 | 0.69378 | 3 | 0 | 3 |
| ETV3 | FEN1 | 0.682012 | 3 | 0 | 3 |
| ETV3 | FTCD | 0.677699 | 3 | 0 | 3 |
| ETV3 | TATDN3 | 0.666157 | 3 | 0 | 3 |
| ETV3 | CDK12 | 0.664462 | 3 | 0 | 3 |
| ETV3 | RUSC1 | 0.658531 | 3 | 0 | 3 |
For details and further investigation, click here
