| Full name: coiled-coil domain containing 58 | Alias Symbol: FLJ33273 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 131076 | HGNC ID: HGNC:31136 | Ensembl Gene: ENSG00000160124 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC58:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC58 | 131076 | 235244_at | 0.3226 | 0.7858 | |
| GSE26886 | CCDC58 | 131076 | 235244_at | -0.3444 | 0.3432 | |
| GSE45670 | CCDC58 | 131076 | 235244_at | 0.8272 | 0.0071 | |
| GSE53622 | CCDC58 | 131076 | 29360 | 0.3852 | 0.0000 | |
| GSE53624 | CCDC58 | 131076 | 29360 | 0.6657 | 0.0000 | |
| GSE63941 | CCDC58 | 131076 | 235244_at | -0.5876 | 0.6621 | |
| GSE77861 | CCDC58 | 131076 | 235244_at | 0.1293 | 0.6329 | |
| GSE97050 | CCDC58 | 131076 | A_32_P215113 | 0.5251 | 0.2729 | |
| SRP007169 | CCDC58 | 131076 | RNAseq | 1.3099 | 0.0023 | |
| SRP008496 | CCDC58 | 131076 | RNAseq | 1.0987 | 0.0000 | |
| SRP064894 | CCDC58 | 131076 | RNAseq | 0.6030 | 0.0125 | |
| SRP133303 | CCDC58 | 131076 | RNAseq | 0.6673 | 0.0013 | |
| SRP159526 | CCDC58 | 131076 | RNAseq | 0.5722 | 0.0927 | |
| SRP193095 | CCDC58 | 131076 | RNAseq | 0.1431 | 0.3990 | |
| SRP219564 | CCDC58 | 131076 | RNAseq | 0.5803 | 0.1979 | |
| TCGA | CCDC58 | 131076 | RNAseq | 0.5013 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCDC58 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC58:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC58 | 131076 | 18 | 0 | 12 | |
| GSE20123 | CCDC58 | 131076 | 18 | 0 | 12 | |
| GSE43470 | CCDC58 | 131076 | 20 | 0 | 23 | |
| GSE46452 | CCDC58 | 131076 | 14 | 5 | 40 | |
| GSE47630 | CCDC58 | 131076 | 16 | 5 | 19 | |
| GSE54993 | CCDC58 | 131076 | 2 | 6 | 62 | |
| GSE54994 | CCDC58 | 131076 | 30 | 4 | 19 | |
| GSE60625 | CCDC58 | 131076 | 0 | 6 | 5 | |
| GSE74703 | CCDC58 | 131076 | 16 | 0 | 20 | |
| GSE74704 | CCDC58 | 131076 | 13 | 0 | 7 | |
| TCGA | CCDC58 | 131076 | 54 | 6 | 36 |
Total number of gains: 201; Total number of losses: 32; Total Number of normals: 255.
Somatic mutations of CCDC58:
Generating mutation plots.
Highly correlated genes for CCDC58:
Showing top 20/375 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC58 | MARS2 | 0.747986 | 3 | 0 | 3 |
| CCDC58 | ATR | 0.721136 | 5 | 0 | 5 |
| CCDC58 | WIZ | 0.711969 | 3 | 0 | 3 |
| CCDC58 | LRRC58 | 0.711834 | 3 | 0 | 3 |
| CCDC58 | DDX39A | 0.706754 | 4 | 0 | 4 |
| CCDC58 | CDCA3 | 0.706735 | 4 | 0 | 4 |
| CCDC58 | MRPL3 | 0.70176 | 6 | 0 | 5 |
| CCDC58 | GTPBP3 | 0.69952 | 3 | 0 | 3 |
| CCDC58 | XPOT | 0.693143 | 4 | 0 | 4 |
| CCDC58 | GOSR1 | 0.693047 | 3 | 0 | 3 |
| CCDC58 | HMCES | 0.691187 | 3 | 0 | 3 |
| CCDC58 | HJURP | 0.691048 | 4 | 0 | 4 |
| CCDC58 | TRMT2A | 0.690515 | 3 | 0 | 3 |
| CCDC58 | ZNF397 | 0.686085 | 3 | 0 | 3 |
| CCDC58 | ESCO2 | 0.685306 | 4 | 0 | 4 |
| CCDC58 | SLC25A44 | 0.684896 | 3 | 0 | 3 |
| CCDC58 | NUF2 | 0.683601 | 4 | 0 | 4 |
| CCDC58 | BUB1 | 0.682551 | 4 | 0 | 3 |
| CCDC58 | TDP1 | 0.680105 | 3 | 0 | 3 |
| CCDC58 | RUVBL1 | 0.678571 | 5 | 0 | 4 |
For details and further investigation, click here
