| Full name: high density lipoprotein binding protein | Alias Symbol: HBP | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 3069 | HGNC ID: HGNC:4857 | Ensembl Gene: ENSG00000115677 | OMIM ID: 142695 |
| Drug and gene relationship at DGIdb | |||
Expression of HDLBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDLBP | 3069 | 221767_x_at | -0.3413 | 0.2830 | |
| GSE20347 | HDLBP | 3069 | 221767_x_at | -0.5664 | 0.0000 | |
| GSE23400 | HDLBP | 3069 | 200643_at | -0.1468 | 0.0063 | |
| GSE26886 | HDLBP | 3069 | 221767_x_at | -0.3358 | 0.0262 | |
| GSE29001 | HDLBP | 3069 | 221767_x_at | -0.3120 | 0.0855 | |
| GSE38129 | HDLBP | 3069 | 221767_x_at | -0.3245 | 0.0022 | |
| GSE45670 | HDLBP | 3069 | 221767_x_at | -0.1116 | 0.2183 | |
| GSE53622 | HDLBP | 3069 | 30876 | -0.0872 | 0.1416 | |
| GSE53624 | HDLBP | 3069 | 30876 | -0.0129 | 0.7959 | |
| GSE63941 | HDLBP | 3069 | 221767_x_at | -0.4640 | 0.2335 | |
| GSE77861 | HDLBP | 3069 | 221767_x_at | -0.0894 | 0.6596 | |
| GSE97050 | HDLBP | 3069 | A_23_P131417 | 0.1965 | 0.3804 | |
| SRP007169 | HDLBP | 3069 | RNAseq | -0.3942 | 0.1748 | |
| SRP008496 | HDLBP | 3069 | RNAseq | -0.5690 | 0.0067 | |
| SRP064894 | HDLBP | 3069 | RNAseq | -0.0961 | 0.4688 | |
| SRP133303 | HDLBP | 3069 | RNAseq | 0.0591 | 0.7687 | |
| SRP159526 | HDLBP | 3069 | RNAseq | -0.1442 | 0.2649 | |
| SRP193095 | HDLBP | 3069 | RNAseq | -0.2943 | 0.0038 | |
| SRP219564 | HDLBP | 3069 | RNAseq | -0.0232 | 0.9348 | |
| TCGA | HDLBP | 3069 | RNAseq | -0.1674 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HDLBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDLBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDLBP | 3069 | 1 | 12 | 17 | |
| GSE20123 | HDLBP | 3069 | 1 | 12 | 17 | |
| GSE43470 | HDLBP | 3069 | 1 | 9 | 33 | |
| GSE46452 | HDLBP | 3069 | 0 | 5 | 54 | |
| GSE47630 | HDLBP | 3069 | 4 | 5 | 31 | |
| GSE54993 | HDLBP | 3069 | 4 | 3 | 63 | |
| GSE54994 | HDLBP | 3069 | 8 | 9 | 36 | |
| GSE60625 | HDLBP | 3069 | 0 | 3 | 8 | |
| GSE74703 | HDLBP | 3069 | 1 | 7 | 28 | |
| GSE74704 | HDLBP | 3069 | 1 | 5 | 14 | |
| TCGA | HDLBP | 3069 | 12 | 28 | 56 |
Total number of gains: 33; Total number of losses: 98; Total Number of normals: 357.
Somatic mutations of HDLBP:
Generating mutation plots.
Highly correlated genes for HDLBP:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDLBP | MIR210HG | 0.707152 | 3 | 0 | 3 |
| HDLBP | ATP6V1C2 | 0.684095 | 3 | 0 | 3 |
| HDLBP | LZTS1 | 0.661386 | 3 | 0 | 3 |
| HDLBP | METRNL | 0.658842 | 3 | 0 | 3 |
| HDLBP | USO1 | 0.655725 | 4 | 0 | 4 |
| HDLBP | SRD5A1 | 0.653732 | 3 | 0 | 3 |
| HDLBP | BOK | 0.650534 | 5 | 0 | 3 |
| HDLBP | DCAF10 | 0.636297 | 3 | 0 | 3 |
| HDLBP | CCDC125 | 0.632093 | 3 | 0 | 3 |
| HDLBP | TAMM41 | 0.631569 | 3 | 0 | 3 |
| HDLBP | CCL17 | 0.63069 | 3 | 0 | 3 |
| HDLBP | OPTN | 0.62899 | 3 | 0 | 3 |
| HDLBP | SAMD10 | 0.623159 | 4 | 0 | 3 |
| HDLBP | ARPC2 | 0.62043 | 8 | 0 | 7 |
| HDLBP | NSDHL | 0.617668 | 4 | 0 | 4 |
| HDLBP | TBC1D10A | 0.616869 | 3 | 0 | 3 |
| HDLBP | AGPAT2 | 0.616331 | 3 | 0 | 3 |
| HDLBP | PLA2G3 | 0.612123 | 3 | 0 | 3 |
| HDLBP | KLHL2 | 0.611329 | 4 | 0 | 3 |
| HDLBP | EIF4E2 | 0.607624 | 9 | 0 | 8 |
For details and further investigation, click here
