| Full name: homeobox and leucine zipper encoding | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 57594 | HGNC ID: HGNC:20164 | Ensembl Gene: ENSG00000215271 | OMIM ID: 608119 |
| Drug and gene relationship at DGIdb | |||
Expression of HOMEZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOMEZ | 57594 | 231868_at | 0.0321 | 0.9140 | |
| GSE26886 | HOMEZ | 57594 | 231868_at | -0.1371 | 0.4152 | |
| GSE45670 | HOMEZ | 57594 | 231868_at | 0.1825 | 0.3071 | |
| GSE53622 | HOMEZ | 57594 | 105821 | -0.1287 | 0.2168 | |
| GSE53624 | HOMEZ | 57594 | 105821 | -0.1340 | 0.1136 | |
| GSE63941 | HOMEZ | 57594 | 231868_at | 0.6656 | 0.1498 | |
| GSE77861 | HOMEZ | 57594 | 231868_at | 0.0243 | 0.8940 | |
| GSE97050 | HOMEZ | 57594 | A_24_P40594 | -0.3084 | 0.1712 | |
| SRP007169 | HOMEZ | 57594 | RNAseq | -0.3200 | 0.3834 | |
| SRP008496 | HOMEZ | 57594 | RNAseq | -0.4565 | 0.0439 | |
| SRP064894 | HOMEZ | 57594 | RNAseq | -0.2081 | 0.3301 | |
| SRP133303 | HOMEZ | 57594 | RNAseq | 0.1288 | 0.6450 | |
| SRP159526 | HOMEZ | 57594 | RNAseq | -0.4280 | 0.0910 | |
| SRP193095 | HOMEZ | 57594 | RNAseq | -0.0756 | 0.6748 | |
| SRP219564 | HOMEZ | 57594 | RNAseq | -0.2330 | 0.5434 | |
| TCGA | HOMEZ | 57594 | RNAseq | -0.0488 | 0.4942 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HOMEZ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOMEZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOMEZ | 57594 | 9 | 1 | 20 | |
| GSE20123 | HOMEZ | 57594 | 9 | 1 | 20 | |
| GSE43470 | HOMEZ | 57594 | 7 | 2 | 34 | |
| GSE46452 | HOMEZ | 57594 | 17 | 2 | 40 | |
| GSE47630 | HOMEZ | 57594 | 11 | 10 | 19 | |
| GSE54993 | HOMEZ | 57594 | 3 | 11 | 56 | |
| GSE54994 | HOMEZ | 57594 | 18 | 5 | 30 | |
| GSE60625 | HOMEZ | 57594 | 0 | 2 | 9 | |
| GSE74703 | HOMEZ | 57594 | 6 | 2 | 28 | |
| GSE74704 | HOMEZ | 57594 | 4 | 1 | 15 | |
| TCGA | HOMEZ | 57594 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of HOMEZ:
Generating mutation plots.
Highly correlated genes for HOMEZ:
Showing top 20/72 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOMEZ | KHNYN | 0.698344 | 4 | 0 | 3 |
| HOMEZ | ARV1 | 0.69271 | 3 | 0 | 3 |
| HOMEZ | EIF3E | 0.666926 | 3 | 0 | 3 |
| HOMEZ | RBM23 | 0.665222 | 4 | 0 | 3 |
| HOMEZ | SAP18 | 0.665106 | 3 | 0 | 3 |
| HOMEZ | XRRA1 | 0.663857 | 3 | 0 | 3 |
| HOMEZ | ZC3HAV1 | 0.663481 | 3 | 0 | 3 |
| HOMEZ | PPP1R16A | 0.662187 | 3 | 0 | 3 |
| HOMEZ | CASP8AP2 | 0.654169 | 3 | 0 | 3 |
| HOMEZ | CLMN | 0.652022 | 3 | 0 | 3 |
| HOMEZ | DHRS4L2 | 0.648886 | 3 | 0 | 3 |
| HOMEZ | UPF1 | 0.647317 | 3 | 0 | 3 |
| HOMEZ | MTUS1 | 0.644674 | 3 | 0 | 3 |
| HOMEZ | FLOT2 | 0.632808 | 3 | 0 | 3 |
| HOMEZ | AKT1 | 0.624157 | 3 | 0 | 3 |
| HOMEZ | HDAC11 | 0.622396 | 4 | 0 | 3 |
| HOMEZ | PPME1 | 0.620843 | 3 | 0 | 3 |
| HOMEZ | ELMOD3 | 0.618027 | 3 | 0 | 3 |
| HOMEZ | ZBTB25 | 0.616435 | 3 | 0 | 3 |
| HOMEZ | KRTCAP2 | 0.613814 | 3 | 0 | 3 |
For details and further investigation, click here
