| Full name: homeobox A1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.2 | ||
| Entrez ID: 3198 | HGNC ID: HGNC:5099 | Ensembl Gene: ENSG00000105991 | OMIM ID: 142955 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXA1 | 3198 | 214639_s_at | 0.2487 | 0.7918 | |
| GSE20347 | HOXA1 | 3198 | 214639_s_at | -0.1324 | 0.5313 | |
| GSE23400 | HOXA1 | 3198 | 214639_s_at | 0.1627 | 0.0348 | |
| GSE26886 | HOXA1 | 3198 | 214639_s_at | -0.5682 | 0.0609 | |
| GSE29001 | HOXA1 | 3198 | 214639_s_at | -0.0689 | 0.8475 | |
| GSE38129 | HOXA1 | 3198 | 214639_s_at | 0.2839 | 0.2062 | |
| GSE45670 | HOXA1 | 3198 | 214639_s_at | 0.3820 | 0.0154 | |
| GSE53622 | HOXA1 | 3198 | 52316 | 0.1761 | 0.3757 | |
| GSE53624 | HOXA1 | 3198 | 52316 | 0.0952 | 0.4620 | |
| GSE63941 | HOXA1 | 3198 | 214639_s_at | 1.6997 | 0.0916 | |
| GSE77861 | HOXA1 | 3198 | 214639_s_at | -0.3591 | 0.3579 | |
| SRP064894 | HOXA1 | 3198 | RNAseq | -0.0330 | 0.9033 | |
| SRP133303 | HOXA1 | 3198 | RNAseq | 0.2941 | 0.2693 | |
| SRP159526 | HOXA1 | 3198 | RNAseq | -0.8501 | 0.0066 | |
| SRP219564 | HOXA1 | 3198 | RNAseq | -0.1662 | 0.8052 | |
| TCGA | HOXA1 | 3198 | RNAseq | 1.2355 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HOXA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXA1 | 3198 | 16 | 1 | 13 | |
| GSE20123 | HOXA1 | 3198 | 16 | 1 | 13 | |
| GSE43470 | HOXA1 | 3198 | 4 | 0 | 39 | |
| GSE46452 | HOXA1 | 3198 | 10 | 2 | 47 | |
| GSE47630 | HOXA1 | 3198 | 8 | 1 | 31 | |
| GSE54993 | HOXA1 | 3198 | 0 | 6 | 64 | |
| GSE54994 | HOXA1 | 3198 | 21 | 2 | 30 | |
| GSE60625 | HOXA1 | 3198 | 0 | 0 | 11 | |
| GSE74703 | HOXA1 | 3198 | 4 | 0 | 32 | |
| GSE74704 | HOXA1 | 3198 | 10 | 1 | 9 | |
| TCGA | HOXA1 | 3198 | 54 | 7 | 35 |
Total number of gains: 143; Total number of losses: 21; Total Number of normals: 324.
Somatic mutations of HOXA1:
Generating mutation plots.
Highly correlated genes for HOXA1:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXA1 | FOPNL | 0.704886 | 3 | 0 | 3 |
| HOXA1 | FAM83A | 0.658239 | 3 | 0 | 3 |
| HOXA1 | BTBD11 | 0.658193 | 3 | 0 | 3 |
| HOXA1 | TTC23 | 0.643475 | 4 | 0 | 4 |
| HOXA1 | IL1RAP | 0.625879 | 4 | 0 | 3 |
| HOXA1 | GJB3 | 0.623385 | 4 | 0 | 3 |
| HOXA1 | ATP10D | 0.622893 | 5 | 0 | 4 |
| HOXA1 | TGFA | 0.621415 | 4 | 0 | 3 |
| HOXA1 | SKAP2 | 0.620505 | 3 | 0 | 3 |
| HOXA1 | RNF40 | 0.618304 | 3 | 0 | 3 |
| HOXA1 | PALB2 | 0.61742 | 4 | 0 | 4 |
| HOXA1 | TMEM41B | 0.603715 | 5 | 0 | 4 |
| HOXA1 | TACSTD2 | 0.590998 | 4 | 0 | 3 |
| HOXA1 | ANXA2 | 0.589404 | 5 | 0 | 4 |
| HOXA1 | VSNL1 | 0.581683 | 5 | 0 | 3 |
| HOXA1 | CCNYL1 | 0.581658 | 3 | 0 | 3 |
| HOXA1 | GJB2 | 0.578364 | 3 | 0 | 3 |
| HOXA1 | JUP | 0.571546 | 5 | 0 | 3 |
| HOXA1 | SLC11A2 | 0.568775 | 3 | 0 | 3 |
| HOXA1 | LPAR5 | 0.565392 | 5 | 0 | 3 |
For details and further investigation, click here
