| Full name: homeobox B13 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 10481 | HGNC ID: HGNC:5112 | Ensembl Gene: ENSG00000159184 | OMIM ID: 604607 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HOXB13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB13 | 10481 | 230105_at | 0.0887 | 0.7523 | |
| GSE20347 | HOXB13 | 10481 | 209844_at | 0.1611 | 0.4404 | |
| GSE23400 | HOXB13 | 10481 | 209844_at | -0.0087 | 0.7958 | |
| GSE26886 | HOXB13 | 10481 | 230105_at | 0.2468 | 0.2455 | |
| GSE29001 | HOXB13 | 10481 | 209844_at | -0.0732 | 0.5591 | |
| GSE38129 | HOXB13 | 10481 | 209844_at | 0.0738 | 0.6890 | |
| GSE45670 | HOXB13 | 10481 | 230105_at | 0.3492 | 0.0024 | |
| GSE53622 | HOXB13 | 10481 | 44457 | 1.5297 | 0.0000 | |
| GSE53624 | HOXB13 | 10481 | 44457 | 1.5021 | 0.0000 | |
| GSE63941 | HOXB13 | 10481 | 209844_at | 0.8205 | 0.1245 | |
| GSE77861 | HOXB13 | 10481 | 209844_at | -0.0128 | 0.9133 | |
| TCGA | HOXB13 | 10481 | RNAseq | 1.6865 | 0.0181 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by HOXB13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB13 | 10481 | 6 | 2 | 22 | |
| GSE20123 | HOXB13 | 10481 | 6 | 2 | 22 | |
| GSE43470 | HOXB13 | 10481 | 3 | 0 | 40 | |
| GSE46452 | HOXB13 | 10481 | 32 | 0 | 27 | |
| GSE47630 | HOXB13 | 10481 | 9 | 0 | 31 | |
| GSE54993 | HOXB13 | 10481 | 2 | 4 | 64 | |
| GSE54994 | HOXB13 | 10481 | 10 | 6 | 37 | |
| GSE60625 | HOXB13 | 10481 | 4 | 0 | 7 | |
| GSE74703 | HOXB13 | 10481 | 3 | 0 | 33 | |
| GSE74704 | HOXB13 | 10481 | 4 | 1 | 15 | |
| TCGA | HOXB13 | 10481 | 27 | 6 | 63 |
Total number of gains: 106; Total number of losses: 21; Total Number of normals: 361.
Somatic mutations of HOXB13:
Generating mutation plots.
Highly correlated genes for HOXB13:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB13 | FGF3 | 0.689643 | 5 | 0 | 3 |
| HOXB13 | SULT1E1 | 0.618747 | 4 | 0 | 3 |
| HOXB13 | SPIB | 0.6082 | 6 | 0 | 3 |
| HOXB13 | ATP8A2 | 0.606185 | 6 | 0 | 5 |
| HOXB13 | CLDN3 | 0.602191 | 4 | 0 | 3 |
| HOXB13 | CXorf58 | 0.582774 | 3 | 0 | 3 |
| HOXB13 | CSN2 | 0.573656 | 6 | 0 | 3 |
| HOXB13 | PADI2 | 0.571381 | 6 | 0 | 3 |
| HOXB13 | PRDM9 | 0.568081 | 4 | 0 | 3 |
| HOXB13 | FABP7 | 0.562928 | 6 | 0 | 3 |
| HOXB13 | CSN3 | 0.561227 | 7 | 0 | 3 |
| HOXB13 | TCTN1 | 0.559345 | 4 | 0 | 3 |
| HOXB13 | CAPN6 | 0.558041 | 4 | 0 | 3 |
| HOXB13 | GDF5 | 0.55126 | 3 | 0 | 3 |
| HOXB13 | ARNT2 | 0.549586 | 6 | 0 | 3 |
| HOXB13 | TTLL4 | 0.54905 | 6 | 0 | 3 |
| HOXB13 | LRP6 | 0.548221 | 6 | 0 | 3 |
| HOXB13 | UPK3A | 0.542982 | 6 | 0 | 3 |
| HOXB13 | FZD9 | 0.538028 | 4 | 0 | 3 |
| HOXB13 | FGF4 | 0.537736 | 5 | 0 | 3 |
For details and further investigation, click here
