| Full name: thioredoxin domain containing 11 | Alias Symbol: EFP1 | ||
| Type: protein-coding gene | Cytoband: 16p13.13 | ||
| Entrez ID: 51061 | HGNC ID: HGNC:28030 | Ensembl Gene: ENSG00000153066 | OMIM ID: 617792 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNDC11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC11 | 51061 | 223325_at | -0.2179 | 0.5682 | |
| GSE26886 | TXNDC11 | 51061 | 223325_at | -0.3500 | 0.0552 | |
| GSE45670 | TXNDC11 | 51061 | 223325_at | 0.2037 | 0.0770 | |
| GSE53622 | TXNDC11 | 51061 | 26776 | 0.1869 | 0.0115 | |
| GSE53624 | TXNDC11 | 51061 | 74983 | 0.0573 | 0.4323 | |
| GSE63941 | TXNDC11 | 51061 | 223325_at | 0.0472 | 0.8682 | |
| GSE77861 | TXNDC11 | 51061 | 223325_at | -0.1219 | 0.3806 | |
| GSE97050 | TXNDC11 | 51061 | A_33_P3386995 | 0.4726 | 0.2192 | |
| SRP007169 | TXNDC11 | 51061 | RNAseq | -0.4304 | 0.2579 | |
| SRP008496 | TXNDC11 | 51061 | RNAseq | -0.2948 | 0.1744 | |
| SRP064894 | TXNDC11 | 51061 | RNAseq | 0.1155 | 0.5304 | |
| SRP133303 | TXNDC11 | 51061 | RNAseq | 0.4411 | 0.0026 | |
| SRP159526 | TXNDC11 | 51061 | RNAseq | 0.1748 | 0.5464 | |
| SRP193095 | TXNDC11 | 51061 | RNAseq | -0.0824 | 0.6424 | |
| SRP219564 | TXNDC11 | 51061 | RNAseq | 0.2973 | 0.1592 | |
| TCGA | TXNDC11 | 51061 | RNAseq | -0.1713 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TXNDC11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC11 | 51061 | 5 | 4 | 21 | |
| GSE20123 | TXNDC11 | 51061 | 5 | 3 | 22 | |
| GSE43470 | TXNDC11 | 51061 | 3 | 3 | 37 | |
| GSE46452 | TXNDC11 | 51061 | 38 | 1 | 20 | |
| GSE47630 | TXNDC11 | 51061 | 14 | 6 | 20 | |
| GSE54993 | TXNDC11 | 51061 | 3 | 5 | 62 | |
| GSE54994 | TXNDC11 | 51061 | 5 | 9 | 39 | |
| GSE60625 | TXNDC11 | 51061 | 4 | 0 | 7 | |
| GSE74703 | TXNDC11 | 51061 | 3 | 2 | 31 | |
| GSE74704 | TXNDC11 | 51061 | 2 | 1 | 17 | |
| TCGA | TXNDC11 | 51061 | 21 | 12 | 63 |
Total number of gains: 103; Total number of losses: 46; Total Number of normals: 339.
Somatic mutations of TXNDC11:
Generating mutation plots.
Highly correlated genes for TXNDC11:
Showing top 20/146 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC11 | CREBL2 | 0.724329 | 3 | 0 | 3 |
| TXNDC11 | STEAP4 | 0.72132 | 3 | 0 | 3 |
| TXNDC11 | HOXB2 | 0.718934 | 3 | 0 | 3 |
| TXNDC11 | NCOA7 | 0.71441 | 3 | 0 | 3 |
| TXNDC11 | SLC35A4 | 0.710906 | 3 | 0 | 3 |
| TXNDC11 | RAC1 | 0.707119 | 3 | 0 | 3 |
| TXNDC11 | EEA1 | 0.706179 | 3 | 0 | 3 |
| TXNDC11 | ZNF546 | 0.702535 | 3 | 0 | 3 |
| TXNDC11 | ORMDL3 | 0.702475 | 3 | 0 | 3 |
| TXNDC11 | HLA-DMA | 0.69976 | 3 | 0 | 3 |
| TXNDC11 | SEMA4A | 0.698454 | 3 | 0 | 3 |
| TXNDC11 | BNIP1 | 0.69844 | 3 | 0 | 3 |
| TXNDC11 | KAT7 | 0.695288 | 3 | 0 | 3 |
| TXNDC11 | KCNA3 | 0.693314 | 3 | 0 | 3 |
| TXNDC11 | MAT2B | 0.688762 | 3 | 0 | 3 |
| TXNDC11 | SEC63 | 0.682978 | 3 | 0 | 3 |
| TXNDC11 | NSMCE1 | 0.681781 | 3 | 0 | 3 |
| TXNDC11 | PFDN1 | 0.678872 | 3 | 0 | 3 |
| TXNDC11 | JUP | 0.678009 | 3 | 0 | 3 |
| TXNDC11 | ACO2 | 0.676871 | 3 | 0 | 3 |
For details and further investigation, click here
