| Full name: ectonucleoside triphosphate diphosphohydrolase 3 | Alias Symbol: NTPDase-3|HB6 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 956 | HGNC ID: HGNC:3365 | Ensembl Gene: ENSG00000168032 | OMIM ID: 603161 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD3 | 956 | 206191_at | -0.2114 | 0.8620 | |
| GSE20347 | ENTPD3 | 956 | 206191_at | -0.3844 | 0.0789 | |
| GSE23400 | ENTPD3 | 956 | 206191_at | -0.0822 | 0.2935 | |
| GSE26886 | ENTPD3 | 956 | 206191_at | -0.5903 | 0.1602 | |
| GSE29001 | ENTPD3 | 956 | 206191_at | -0.3640 | 0.2631 | |
| GSE38129 | ENTPD3 | 956 | 206191_at | 0.0290 | 0.9249 | |
| GSE45670 | ENTPD3 | 956 | 206191_at | 0.0072 | 0.9860 | |
| GSE53622 | ENTPD3 | 956 | 108798 | -0.4902 | 0.0156 | |
| GSE53624 | ENTPD3 | 956 | 108798 | -0.5957 | 0.0050 | |
| GSE63941 | ENTPD3 | 956 | 206191_at | 1.2536 | 0.1745 | |
| GSE77861 | ENTPD3 | 956 | 206191_at | 0.0996 | 0.8117 | |
| GSE97050 | ENTPD3 | 956 | A_23_P212469 | -0.0356 | 0.9006 | |
| SRP007169 | ENTPD3 | 956 | RNAseq | -0.1657 | 0.7715 | |
| SRP008496 | ENTPD3 | 956 | RNAseq | 0.2659 | 0.4622 | |
| SRP064894 | ENTPD3 | 956 | RNAseq | -0.8893 | 0.0169 | |
| SRP133303 | ENTPD3 | 956 | RNAseq | -0.8366 | 0.0024 | |
| SRP159526 | ENTPD3 | 956 | RNAseq | 0.3114 | 0.5808 | |
| SRP193095 | ENTPD3 | 956 | RNAseq | -0.2878 | 0.2711 | |
| SRP219564 | ENTPD3 | 956 | RNAseq | -0.6601 | 0.3126 | |
| TCGA | ENTPD3 | 956 | RNAseq | 0.0996 | 0.6209 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ENTPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD3 | 956 | 0 | 19 | 11 | |
| GSE20123 | ENTPD3 | 956 | 0 | 19 | 11 | |
| GSE43470 | ENTPD3 | 956 | 0 | 20 | 23 | |
| GSE46452 | ENTPD3 | 956 | 2 | 17 | 40 | |
| GSE47630 | ENTPD3 | 956 | 2 | 24 | 14 | |
| GSE54993 | ENTPD3 | 956 | 7 | 2 | 61 | |
| GSE54994 | ENTPD3 | 956 | 1 | 33 | 19 | |
| GSE60625 | ENTPD3 | 956 | 5 | 0 | 6 | |
| GSE74703 | ENTPD3 | 956 | 0 | 16 | 20 | |
| GSE74704 | ENTPD3 | 956 | 0 | 13 | 7 | |
| TCGA | ENTPD3 | 956 | 1 | 71 | 24 |
Total number of gains: 18; Total number of losses: 234; Total Number of normals: 236.
Somatic mutations of ENTPD3:
Generating mutation plots.
Highly correlated genes for ENTPD3:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD3 | AVEN | 0.761239 | 3 | 0 | 3 |
| ENTPD3 | FGGY | 0.721596 | 3 | 0 | 3 |
| ENTPD3 | EIF3J | 0.719648 | 3 | 0 | 3 |
| ENTPD3 | PCBP1 | 0.715961 | 3 | 0 | 3 |
| ENTPD3 | MARS2 | 0.709458 | 3 | 0 | 3 |
| ENTPD3 | IREB2 | 0.705783 | 3 | 0 | 3 |
| ENTPD3 | MAPK6 | 0.69168 | 3 | 0 | 3 |
| ENTPD3 | CUL2 | 0.691503 | 3 | 0 | 3 |
| ENTPD3 | WDR47 | 0.683253 | 4 | 0 | 3 |
| ENTPD3 | TTC23 | 0.680475 | 4 | 0 | 3 |
| ENTPD3 | TMCC3 | 0.66892 | 3 | 0 | 3 |
| ENTPD3 | C3orf38 | 0.659259 | 3 | 0 | 3 |
| ENTPD3 | USP8 | 0.657835 | 4 | 0 | 4 |
| ENTPD3 | HSPA4L | 0.656306 | 4 | 0 | 4 |
| ENTPD3 | POLE3 | 0.653425 | 3 | 0 | 3 |
| ENTPD3 | SETX | 0.648537 | 3 | 0 | 3 |
| ENTPD3 | RAD50 | 0.64832 | 3 | 0 | 3 |
| ENTPD3 | EPB41 | 0.647482 | 3 | 0 | 3 |
| ENTPD3 | CBR1 | 0.647113 | 9 | 0 | 9 |
| ENTPD3 | SPPL2A | 0.645698 | 4 | 0 | 4 |
For details and further investigation, click here
