| Full name: RAD54 homolog B | Alias Symbol: RDH54 | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 25788 | HGNC ID: HGNC:17228 | Ensembl Gene: ENSG00000197275 | OMIM ID: 604289 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAD54B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD54B | 25788 | 219494_at | 1.3670 | 0.0152 | |
| GSE20347 | RAD54B | 25788 | 219494_at | 1.4983 | 0.0000 | |
| GSE23400 | RAD54B | 25788 | 219494_at | 0.7752 | 0.0000 | |
| GSE26886 | RAD54B | 25788 | 219494_at | 0.2010 | 0.5534 | |
| GSE29001 | RAD54B | 25788 | 219494_at | 0.8667 | 0.0045 | |
| GSE38129 | RAD54B | 25788 | 219494_at | 1.5600 | 0.0000 | |
| GSE45670 | RAD54B | 25788 | 219494_at | 0.9484 | 0.0000 | |
| GSE53622 | RAD54B | 25788 | 20759 | 1.4323 | 0.0000 | |
| GSE53624 | RAD54B | 25788 | 77092 | 1.1696 | 0.0000 | |
| GSE63941 | RAD54B | 25788 | 219494_at | 1.6982 | 0.0131 | |
| GSE77861 | RAD54B | 25788 | 219494_at | 0.4960 | 0.0985 | |
| GSE97050 | RAD54B | 25788 | A_23_P94141 | -0.0462 | 0.8494 | |
| SRP007169 | RAD54B | 25788 | RNAseq | 0.8917 | 0.0258 | |
| SRP008496 | RAD54B | 25788 | RNAseq | 0.6892 | 0.0226 | |
| SRP064894 | RAD54B | 25788 | RNAseq | 1.1352 | 0.0001 | |
| SRP133303 | RAD54B | 25788 | RNAseq | 1.3162 | 0.0000 | |
| SRP159526 | RAD54B | 25788 | RNAseq | 1.1491 | 0.0019 | |
| SRP193095 | RAD54B | 25788 | RNAseq | 0.8385 | 0.0000 | |
| SRP219564 | RAD54B | 25788 | RNAseq | 0.5918 | 0.2047 | |
| TCGA | RAD54B | 25788 | RNAseq | 0.8046 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by RAD54B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAD54B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD54B | 25788 | 16 | 0 | 14 | |
| GSE20123 | RAD54B | 25788 | 17 | 0 | 13 | |
| GSE43470 | RAD54B | 25788 | 21 | 1 | 21 | |
| GSE46452 | RAD54B | 25788 | 22 | 0 | 37 | |
| GSE47630 | RAD54B | 25788 | 24 | 0 | 16 | |
| GSE54993 | RAD54B | 25788 | 0 | 20 | 50 | |
| GSE54994 | RAD54B | 25788 | 34 | 1 | 18 | |
| GSE60625 | RAD54B | 25788 | 0 | 4 | 7 | |
| GSE74703 | RAD54B | 25788 | 18 | 1 | 17 | |
| GSE74704 | RAD54B | 25788 | 12 | 0 | 8 | |
| TCGA | RAD54B | 25788 | 56 | 1 | 39 |
Total number of gains: 220; Total number of losses: 28; Total Number of normals: 240.
Somatic mutations of RAD54B:
Generating mutation plots.
Highly correlated genes for RAD54B:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD54B | BUB1B | 0.800126 | 9 | 0 | 9 |
| RAD54B | CDCA5 | 0.794489 | 7 | 0 | 7 |
| RAD54B | CDK1 | 0.786066 | 10 | 0 | 10 |
| RAD54B | RAD51AP1 | 0.773758 | 11 | 0 | 11 |
| RAD54B | CKS1B | 0.770261 | 10 | 0 | 10 |
| RAD54B | HOXC9 | 0.766528 | 4 | 0 | 4 |
| RAD54B | KNSTRN | 0.764221 | 6 | 0 | 6 |
| RAD54B | ETV3 | 0.762973 | 3 | 0 | 3 |
| RAD54B | FOXM1 | 0.756696 | 10 | 0 | 10 |
| RAD54B | ECT2 | 0.75662 | 11 | 0 | 10 |
| RAD54B | TBC1D31 | 0.753937 | 11 | 0 | 10 |
| RAD54B | KIF4A | 0.75128 | 12 | 0 | 11 |
| RAD54B | MTERF3 | 0.749786 | 9 | 0 | 8 |
| RAD54B | KIF2C | 0.748851 | 11 | 0 | 10 |
| RAD54B | CDC6 | 0.747674 | 9 | 0 | 9 |
| RAD54B | CDC20 | 0.744254 | 11 | 0 | 11 |
| RAD54B | ZWINT | 0.741274 | 11 | 0 | 11 |
| RAD54B | HAUS8 | 0.740217 | 7 | 0 | 7 |
| RAD54B | TRIP13 | 0.735048 | 11 | 0 | 10 |
| RAD54B | RFC4 | 0.732311 | 11 | 0 | 10 |
For details and further investigation, click here
