| Full name: methyltransferase like 2A | Alias Symbol: FLJ12760|METTL2 | ||
| Type: protein-coding gene | Cytoband: 17q23.2 | ||
| Entrez ID: 339175 | HGNC ID: HGNC:25755 | Ensembl Gene: ENSG00000087995 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of METTL2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | METTL2A | 339175 | 1801 | 0.4787 | 0.0000 | |
| GSE53624 | METTL2A | 339175 | 1801 | 0.3611 | 0.0000 | |
| GSE97050 | METTL2A | 339175 | A_32_P725218 | 0.6391 | 0.0828 | |
| SRP007169 | METTL2A | 339175 | RNAseq | 0.1978 | 0.5838 | |
| SRP008496 | METTL2A | 339175 | RNAseq | 0.0206 | 0.9207 | |
| SRP064894 | METTL2A | 339175 | RNAseq | 0.5767 | 0.0022 | |
| SRP133303 | METTL2A | 339175 | RNAseq | 0.5666 | 0.0119 | |
| SRP159526 | METTL2A | 339175 | RNAseq | 0.5769 | 0.0198 | |
| SRP193095 | METTL2A | 339175 | RNAseq | -0.0109 | 0.8807 | |
| SRP219564 | METTL2A | 339175 | RNAseq | 0.3010 | 0.3864 | |
| TCGA | METTL2A | 339175 | RNAseq | 0.0080 | 0.8880 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by METTL2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL2A | 339175 | 4 | 1 | 25 | |
| GSE20123 | METTL2A | 339175 | 4 | 1 | 25 | |
| GSE43470 | METTL2A | 339175 | 5 | 0 | 38 | |
| GSE46452 | METTL2A | 339175 | 31 | 0 | 28 | |
| GSE47630 | METTL2A | 339175 | 7 | 1 | 32 | |
| GSE54993 | METTL2A | 339175 | 2 | 5 | 63 | |
| GSE54994 | METTL2A | 339175 | 9 | 5 | 39 | |
| GSE60625 | METTL2A | 339175 | 4 | 0 | 7 | |
| GSE74703 | METTL2A | 339175 | 5 | 0 | 31 | |
| GSE74704 | METTL2A | 339175 | 3 | 1 | 16 | |
| TCGA | METTL2A | 339175 | 31 | 7 | 58 |
Total number of gains: 105; Total number of losses: 21; Total Number of normals: 362.
Somatic mutations of METTL2A:
Generating mutation plots.
Highly correlated genes for METTL2A:
Showing top 20/26 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL2A | SENP3 | 0.724473 | 3 | 0 | 3 |
| METTL2A | MAZ | 0.711549 | 3 | 0 | 3 |
| METTL2A | MPHOSPH9 | 0.700561 | 3 | 0 | 3 |
| METTL2A | IMMT | 0.700365 | 3 | 0 | 3 |
| METTL2A | NOP58 | 0.699648 | 3 | 0 | 3 |
| METTL2A | ESF1 | 0.689599 | 3 | 0 | 3 |
| METTL2A | GPATCH2 | 0.688533 | 3 | 0 | 3 |
| METTL2A | NUP88 | 0.684382 | 3 | 0 | 3 |
| METTL2A | MTIF2 | 0.679119 | 3 | 0 | 3 |
| METTL2A | SNRPB2 | 0.677462 | 3 | 0 | 3 |
| METTL2A | CTBP2 | 0.676739 | 3 | 0 | 3 |
| METTL2A | R3HDM1 | 0.674902 | 3 | 0 | 3 |
| METTL2A | DNMT1 | 0.674136 | 3 | 0 | 3 |
| METTL2A | POU2F1 | 0.674061 | 3 | 0 | 3 |
| METTL2A | TOPBP1 | 0.672955 | 3 | 0 | 3 |
| METTL2A | ILF3 | 0.669008 | 3 | 0 | 3 |
| METTL2A | NOP2 | 0.65797 | 3 | 0 | 3 |
| METTL2A | GORAB | 0.647017 | 3 | 0 | 3 |
| METTL2A | RBBP5 | 0.644508 | 4 | 0 | 3 |
| METTL2A | LLPH | 0.633597 | 3 | 0 | 3 |
For details and further investigation, click here
