IMPG2

 

Full name: interphotoreceptor matrix proteoglycan 2 Alias Symbol: IPM200|RP56
Type: protein-coding gene Cytoband: 3q12.3
Entrez ID: 50939 HGNC ID: HGNC:18362 Ensembl Gene: ENSG00000081148 OMIM ID: 607056
Drug and gene relationship at DGIdb

 

Expression of IMPG2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IMPG2 50939 220830_at 0.0328 0.9174
GSE20347 IMPG2 50939 220830_at 0.0184 0.8427
GSE23400 IMPG2 50939 220830_at -0.1321 0.0000
GSE26886 IMPG2 50939 220830_at -0.2088 0.0287
GSE29001 IMPG2 50939 220830_at -0.2263 0.0497
GSE38129 IMPG2 50939 220830_at -0.0411 0.6749
GSE45670 IMPG2 50939 220830_at 0.1227 0.2257
GSE53622 IMPG2 50939 1461 0.0201 0.8445
GSE53624 IMPG2 50939 1461 0.0121 0.9053
GSE63941 IMPG2 50939 220830_at 0.0050 0.9765
GSE77861 IMPG2 50939 220830_at -0.2515 0.1590
SRP064894 IMPG2 50939 RNAseq 0.5655 0.0336
SRP133303 IMPG2 50939 RNAseq -0.2621 0.1003
SRP159526 IMPG2 50939 RNAseq -0.4767 0.4629
SRP193095 IMPG2 50939 RNAseq -0.0253 0.8926
SRP219564 IMPG2 50939 RNAseq -0.2924 0.6060
TCGA IMPG2 50939 RNAseq -0.1730 0.7236

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by IMPG2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of IMPG2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IMPG2 50939 17 1 12
GSE20123 IMPG2 50939 16 1 13
GSE43470 IMPG2 50939 19 1 23
GSE46452 IMPG2 50939 12 6 41
GSE47630 IMPG2 50939 16 6 18
GSE54993 IMPG2 50939 2 5 63
GSE54994 IMPG2 50939 27 5 21
GSE60625 IMPG2 50939 0 6 5
GSE74703 IMPG2 50939 15 1 20
GSE74704 IMPG2 50939 13 1 6
TCGA IMPG2 50939 48 9 39

Total number of gains: 185; Total number of losses: 42; Total Number of normals: 261.  


 

Somatic mutations of IMPG2:

 

Generating mutation plots.

 

Highly correlated genes for IMPG2:

 

Showing top 20/904 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IMPG2KHDRBS20.708484404
IMPG2TRPM50.682195303
IMPG2CER10.673997404
IMPG2GJA30.672812303
IMPG2EPHA50.672689404
IMPG2MC5R0.666403303
IMPG2PTH1R0.666274303
IMPG2CYP2W10.665513404
IMPG2OR12D20.664127505
IMPG2SST0.663882303
IMPG2EPS8L30.663705303
IMPG2IFNA40.662352404
IMPG2GABRR20.660516404
IMPG2KIR2DS20.659258605
IMPG2FGA0.658914504
IMPG2UTF10.655329303
IMPG2RGR0.654097505
IMPG2ARPC20.651055303
IMPG2ORMDL20.65104303
IMPG2TSHB0.650567604

For details and further investigation, click here