| Full name: inositol hexakisphosphate kinase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51447 | HGNC ID: HGNC:17313 | Ensembl Gene: ENSG00000068745 | OMIM ID: 606992 |
| Drug and gene relationship at DGIdb | |||
Expression of IP6K2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IP6K2 | 51447 | 223165_s_at | 0.2259 | 0.5282 | |
| GSE20347 | IP6K2 | 51447 | 218192_at | -0.1323 | 0.3115 | |
| GSE23400 | IP6K2 | 51447 | 218192_at | -0.1361 | 0.0055 | |
| GSE26886 | IP6K2 | 51447 | 223165_s_at | -0.5714 | 0.0032 | |
| GSE29001 | IP6K2 | 51447 | 218192_at | -0.4242 | 0.1794 | |
| GSE38129 | IP6K2 | 51447 | 218192_at | -0.1619 | 0.0890 | |
| GSE45670 | IP6K2 | 51447 | 223165_s_at | 0.0123 | 0.9615 | |
| GSE53622 | IP6K2 | 51447 | 118370 | -0.2532 | 0.0228 | |
| GSE53624 | IP6K2 | 51447 | 118370 | -0.5110 | 0.0000 | |
| GSE63941 | IP6K2 | 51447 | 223165_s_at | 0.3075 | 0.6330 | |
| GSE77861 | IP6K2 | 51447 | 223165_s_at | -0.4719 | 0.1148 | |
| GSE97050 | IP6K2 | 51447 | A_23_P301138 | 0.2992 | 0.2433 | |
| SRP007169 | IP6K2 | 51447 | RNAseq | -0.9252 | 0.0156 | |
| SRP008496 | IP6K2 | 51447 | RNAseq | -0.7688 | 0.0046 | |
| SRP064894 | IP6K2 | 51447 | RNAseq | -0.2805 | 0.0923 | |
| SRP133303 | IP6K2 | 51447 | RNAseq | -0.5200 | 0.0001 | |
| SRP159526 | IP6K2 | 51447 | RNAseq | -0.1842 | 0.5883 | |
| SRP193095 | IP6K2 | 51447 | RNAseq | -0.3590 | 0.0009 | |
| SRP219564 | IP6K2 | 51447 | RNAseq | -0.2840 | 0.4960 | |
| TCGA | IP6K2 | 51447 | RNAseq | -0.0454 | 0.3753 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IP6K2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IP6K2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IP6K2 | 51447 | 0 | 18 | 12 | |
| GSE20123 | IP6K2 | 51447 | 0 | 19 | 11 | |
| GSE43470 | IP6K2 | 51447 | 0 | 19 | 24 | |
| GSE46452 | IP6K2 | 51447 | 3 | 16 | 40 | |
| GSE47630 | IP6K2 | 51447 | 1 | 24 | 15 | |
| GSE54993 | IP6K2 | 51447 | 6 | 2 | 62 | |
| GSE54994 | IP6K2 | 51447 | 0 | 37 | 16 | |
| GSE60625 | IP6K2 | 51447 | 5 | 0 | 6 | |
| GSE74703 | IP6K2 | 51447 | 0 | 15 | 21 | |
| GSE74704 | IP6K2 | 51447 | 0 | 12 | 8 | |
| TCGA | IP6K2 | 51447 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 240; Total Number of normals: 233.
Somatic mutations of IP6K2:
Generating mutation plots.
Highly correlated genes for IP6K2:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IP6K2 | ZNF180 | 0.656372 | 3 | 0 | 3 |
| IP6K2 | MSL2 | 0.651089 | 3 | 0 | 3 |
| IP6K2 | TSTD1 | 0.644618 | 4 | 0 | 3 |
| IP6K2 | SYTL1 | 0.633953 | 6 | 0 | 4 |
| IP6K2 | NIPAL1 | 0.632433 | 3 | 0 | 3 |
| IP6K2 | ZBTB44 | 0.629618 | 3 | 0 | 3 |
| IP6K2 | ZNF740 | 0.629247 | 4 | 0 | 3 |
| IP6K2 | RAD18 | 0.629025 | 3 | 0 | 3 |
| IP6K2 | MYEOV | 0.621595 | 3 | 0 | 3 |
| IP6K2 | PTPN3 | 0.621101 | 5 | 0 | 4 |
| IP6K2 | ELOF1 | 0.616434 | 3 | 0 | 3 |
| IP6K2 | CASP9 | 0.613633 | 5 | 0 | 3 |
| IP6K2 | ARFGAP2 | 0.613611 | 4 | 0 | 4 |
| IP6K2 | SYT17 | 0.61166 | 4 | 0 | 3 |
| IP6K2 | APH1A | 0.607869 | 5 | 0 | 4 |
| IP6K2 | TSEN54 | 0.607712 | 3 | 0 | 3 |
| IP6K2 | ANGEL2 | 0.606578 | 4 | 0 | 3 |
| IP6K2 | CDS1 | 0.602194 | 3 | 0 | 3 |
| IP6K2 | DNAJC5 | 0.599705 | 4 | 0 | 3 |
| IP6K2 | SMARCD2 | 0.595267 | 3 | 0 | 3 |
For details and further investigation, click here
