| Full name: inositol hexakisphosphate kinase 3 | Alias Symbol: INSP6K3 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 117283 | HGNC ID: HGNC:17269 | Ensembl Gene: ENSG00000161896 | OMIM ID: 606993 |
| Drug and gene relationship at DGIdb | |||
Expression of IP6K3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IP6K3 | 117283 | 231179_at | -1.3892 | 0.0374 | |
| GSE26886 | IP6K3 | 117283 | 231179_at | 0.6234 | 0.0007 | |
| GSE45670 | IP6K3 | 117283 | 231179_at | -0.6680 | 0.0016 | |
| GSE53622 | IP6K3 | 117283 | 105748 | -1.6485 | 0.0000 | |
| GSE53624 | IP6K3 | 117283 | 105748 | -2.1260 | 0.0000 | |
| GSE63941 | IP6K3 | 117283 | 231179_at | 0.1182 | 0.4669 | |
| GSE77861 | IP6K3 | 117283 | 231179_at | -0.0817 | 0.4039 | |
| SRP159526 | IP6K3 | 117283 | RNAseq | -3.8966 | 0.0000 | |
| SRP219564 | IP6K3 | 117283 | RNAseq | -2.9230 | 0.0015 | |
| TCGA | IP6K3 | 117283 | RNAseq | -1.8248 | 0.0016 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by IP6K3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IP6K3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IP6K3 | 117283 | 5 | 0 | 25 | |
| GSE20123 | IP6K3 | 117283 | 5 | 0 | 25 | |
| GSE43470 | IP6K3 | 117283 | 4 | 1 | 38 | |
| GSE46452 | IP6K3 | 117283 | 2 | 9 | 48 | |
| GSE47630 | IP6K3 | 117283 | 8 | 4 | 28 | |
| GSE54993 | IP6K3 | 117283 | 3 | 1 | 66 | |
| GSE54994 | IP6K3 | 117283 | 11 | 4 | 38 | |
| GSE60625 | IP6K3 | 117283 | 1 | 0 | 10 | |
| GSE74703 | IP6K3 | 117283 | 4 | 0 | 32 | |
| GSE74704 | IP6K3 | 117283 | 2 | 0 | 18 | |
| TCGA | IP6K3 | 117283 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of IP6K3:
Generating mutation plots.
Highly correlated genes for IP6K3:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IP6K3 | PKHD1L1 | 0.798455 | 3 | 0 | 3 |
| IP6K3 | LGI1 | 0.749534 | 4 | 0 | 4 |
| IP6K3 | ENPP1 | 0.729749 | 3 | 0 | 3 |
| IP6K3 | RGN | 0.685783 | 4 | 0 | 4 |
| IP6K3 | P2RY14 | 0.680121 | 4 | 0 | 4 |
| IP6K3 | BEGAIN | 0.679497 | 3 | 0 | 3 |
| IP6K3 | PDK4 | 0.67862 | 4 | 0 | 4 |
| IP6K3 | ATP1A2 | 0.675991 | 4 | 0 | 4 |
| IP6K3 | PLAC9 | 0.67211 | 4 | 0 | 4 |
| IP6K3 | PGM5 | 0.671828 | 5 | 0 | 5 |
| IP6K3 | ANGPTL1 | 0.668779 | 4 | 0 | 4 |
| IP6K3 | FXYD1 | 0.668707 | 3 | 0 | 3 |
| IP6K3 | ADH1B | 0.656822 | 4 | 0 | 4 |
| IP6K3 | CHRDL1 | 0.655115 | 3 | 0 | 3 |
| IP6K3 | GREM2 | 0.65189 | 6 | 0 | 6 |
| IP6K3 | KLF15 | 0.648051 | 4 | 0 | 3 |
| IP6K3 | PTCHD1 | 0.646886 | 4 | 0 | 4 |
| IP6K3 | KCNB1 | 0.64146 | 3 | 0 | 3 |
| IP6K3 | DPT | 0.640279 | 4 | 0 | 4 |
| IP6K3 | RCAN2 | 0.637973 | 4 | 0 | 4 |
For details and further investigation, click here
