KBTBD11

 

Full name: kelch repeat and BTB domain containing 11 Alias Symbol: KIAA0711|KLHDC7C
Type: protein-coding gene Cytoband: 8p23.3
Entrez ID: 9920 HGNC ID: HGNC:29104 Ensembl Gene: ENSG00000176595 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of KBTBD11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KBTBD11 9920 204301_at -0.7926 0.2836
GSE20347 KBTBD11 9920 204301_at -0.0331 0.7459
GSE23400 KBTBD11 9920 204301_at -0.2493 0.0000
GSE26886 KBTBD11 9920 204301_at 0.1138 0.3730
GSE29001 KBTBD11 9920 204301_at 0.3530 0.2859
GSE38129 KBTBD11 9920 204301_at -0.4309 0.0084
GSE45670 KBTBD11 9920 204301_at -0.5850 0.0018
GSE53622 KBTBD11 9920 31674 -0.7763 0.0000
GSE53624 KBTBD11 9920 31674 -0.4297 0.0112
GSE63941 KBTBD11 9920 204301_at 0.3941 0.6719
GSE77861 KBTBD11 9920 204301_at 0.0594 0.5623
GSE97050 KBTBD11 9920 A_23_P94319 -0.3777 0.2726
SRP007169 KBTBD11 9920 RNAseq 0.7324 0.3390
SRP064894 KBTBD11 9920 RNAseq -0.1552 0.6608
SRP133303 KBTBD11 9920 RNAseq -1.1647 0.0005
SRP159526 KBTBD11 9920 RNAseq 0.3899 0.3383
SRP219564 KBTBD11 9920 RNAseq 0.0241 0.9688
TCGA KBTBD11 9920 RNAseq -1.0341 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by KBTBD11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KBTBD11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KBTBD11 9920 5 13 12
GSE20123 KBTBD11 9920 5 13 12
GSE43470 KBTBD11 9920 5 9 29
GSE46452 KBTBD11 9920 12 14 33
GSE47630 KBTBD11 9920 10 8 22
GSE54993 KBTBD11 9920 4 14 52
GSE54994 KBTBD11 9920 10 18 25
GSE60625 KBTBD11 9920 3 0 8
GSE74703 KBTBD11 9920 5 7 24
GSE74704 KBTBD11 9920 4 8 8
TCGA KBTBD11 9920 14 41 41

Total number of gains: 77; Total number of losses: 145; Total Number of normals: 266.  

 

Somatic mutations of KBTBD11:

 

Generating mutation plots.

 

Highly correlated genes for KBTBD11:

 

Showing top 20/798 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KBTBD11FAT40.790111303
KBTBD11ADAMTS50.774223606
KBTBD11DIXDC10.761266606
KBTBD11LAMA20.754844505
KBTBD11TRIM520.752822303
KBTBD11PDE1A0.748223606
KBTBD11STARD90.739322303
KBTBD11PID10.732738606
KBTBD11FBLN50.729275606
KBTBD11KCTD120.724719606
KBTBD11TMOD10.720998504
KBTBD11LRCH20.720911505
KBTBD11IL11RA0.719076303
KBTBD11JAM30.715702605
KBTBD11ABCA60.714632706
KBTBD11DDR20.709117606
KBTBD11RASSF80.708946403
KBTBD11MCAM0.705983404
KBTBD11FXYD10.704418505
KBTBD11DAPK10.704182403

For details and further investigation, click here