CENPF

 

Full name: centromere protein F Alias Symbol: hcp-1
Type: protein-coding gene Cytoband: 1q41
Entrez ID: 1063 HGNC ID: HGNC:1857 Ensembl Gene: ENSG00000117724 OMIM ID: 600236
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CENPF:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CENPF 1063 207828_s_at 1.7622 0.0215
GSE20347 CENPF 1063 207828_s_at 1.5075 0.0000
GSE23400 CENPF 1063 207828_s_at 1.4145 0.0000
GSE26886 CENPF 1063 207828_s_at 1.3389 0.0000
GSE29001 CENPF 1063 207828_s_at 1.6747 0.0000
GSE38129 CENPF 1063 207828_s_at 1.9762 0.0000
GSE45670 CENPF 1063 207828_s_at 1.4971 0.0000
GSE53622 CENPF 1063 24600 1.6448 0.0000
GSE53624 CENPF 1063 24600 1.9286 0.0000
GSE63941 CENPF 1063 207828_s_at 2.7123 0.0024
GSE77861 CENPF 1063 207828_s_at 1.1206 0.0063
GSE97050 CENPF 1063 A_23_P401 1.5255 0.1413
SRP007169 CENPF 1063 RNAseq 3.7798 0.0000
SRP008496 CENPF 1063 RNAseq 3.3736 0.0000
SRP064894 CENPF 1063 RNAseq 1.6604 0.0000
SRP133303 CENPF 1063 RNAseq 1.6623 0.0000
SRP159526 CENPF 1063 RNAseq 1.6025 0.0002
SRP193095 CENPF 1063 RNAseq 1.0718 0.0000
SRP219564 CENPF 1063 RNAseq 1.2691 0.0658
TCGA CENPF 1063 RNAseq 1.0081 0.0000

Upregulated datasets: 18; Downregulated datasets: 0.  

 

Survival by CENPF expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CENPF:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CENPF 1063 9 1 20
GSE20123 CENPF 1063 9 1 20
GSE43470 CENPF 1063 7 1 35
GSE46452 CENPF 1063 3 1 55
GSE47630 CENPF 1063 15 0 25
GSE54993 CENPF 1063 0 6 64
GSE54994 CENPF 1063 14 0 39
GSE60625 CENPF 1063 0 0 11
GSE74703 CENPF 1063 7 1 28
GSE74704 CENPF 1063 3 1 16
TCGA CENPF 1063 43 4 49

Total number of gains: 110; Total number of losses: 16; Total Number of normals: 362.  

 

Somatic mutations of CENPF:

 

Generating mutation plots.

 

Highly correlated genes for CENPF:

 

Showing top 20/2016 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CENPFNEK20.89573613013
CENPFASPM0.89416313012
CENPFBUB1B0.892045909
CENPFTPX20.88869612012
CENPFKIF4A0.87955511011
CENPFDTL0.86988513012
CENPFNUF20.868385909
CENPFTOP2A0.86709613013
CENPFKIF140.86683613012
CENPFKIF20A0.86530712012
CENPFCKS1B0.86303912012
CENPFTRIP130.85420512012
CENPFCDKN30.85358312012
CENPFCDK10.85344612012
CENPFUBE2T0.849273908
CENPFMCM40.84647212012
CENPFGINS10.846212012
CENPFDLGAP50.84493312012
CENPFNCAPH0.844242909
CENPFGMNN0.84049412012

For details and further investigation, click here