| Full name: keratin 86 | Alias Symbol: MNX|Hb6 | ||
| Type: protein-coding gene | Cytoband: 12q13 | ||
| Entrez ID: 3892 | HGNC ID: HGNC:6463 | Ensembl Gene: ENSG00000170442 | OMIM ID: 601928 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT86:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT86 | 3892 | 215189_at | 0.1562 | 0.4747 | |
| GSE20347 | KRT86 | 3892 | 215189_at | 0.0537 | 0.5744 | |
| GSE23400 | KRT86 | 3892 | 215189_at | -0.0193 | 0.6432 | |
| GSE26886 | KRT86 | 3892 | 215189_at | 0.3785 | 0.0551 | |
| GSE29001 | KRT86 | 3892 | 215189_at | 0.2950 | 0.0645 | |
| GSE38129 | KRT86 | 3892 | 215189_at | 0.0054 | 0.9672 | |
| GSE45670 | KRT86 | 3892 | 215189_at | 0.0473 | 0.7886 | |
| GSE53622 | KRT86 | 3892 | 38057 | 0.3734 | 0.0004 | |
| GSE53624 | KRT86 | 3892 | 38057 | -0.1428 | 0.1909 | |
| GSE63941 | KRT86 | 3892 | 215189_at | 0.8262 | 0.1229 | |
| GSE77861 | KRT86 | 3892 | 215189_at | -0.0989 | 0.3264 | |
| GSE97050 | KRT86 | 3892 | A_23_P363769 | 0.0128 | 0.9706 | |
| SRP219564 | KRT86 | 3892 | RNAseq | 1.1729 | 0.0501 | |
| TCGA | KRT86 | 3892 | RNAseq | 1.9235 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KRT86 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT86:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT86 | 3892 | 8 | 1 | 21 | |
| GSE20123 | KRT86 | 3892 | 8 | 1 | 21 | |
| GSE43470 | KRT86 | 3892 | 3 | 0 | 40 | |
| GSE46452 | KRT86 | 3892 | 7 | 1 | 51 | |
| GSE47630 | KRT86 | 3892 | 10 | 2 | 28 | |
| GSE54993 | KRT86 | 3892 | 0 | 5 | 65 | |
| GSE54994 | KRT86 | 3892 | 3 | 2 | 48 | |
| GSE60625 | KRT86 | 3892 | 0 | 0 | 11 | |
| GSE74703 | KRT86 | 3892 | 3 | 0 | 33 | |
| GSE74704 | KRT86 | 3892 | 5 | 1 | 14 | |
| TCGA | KRT86 | 3892 | 12 | 11 | 73 |
Total number of gains: 59; Total number of losses: 24; Total Number of normals: 405.
Somatic mutations of KRT86:
Generating mutation plots.
Highly correlated genes for KRT86:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT86 | RIT2 | 0.654979 | 3 | 0 | 3 |
| KRT86 | SLC14A1 | 0.644828 | 3 | 0 | 3 |
| KRT86 | CREB3L1 | 0.634616 | 3 | 0 | 3 |
| KRT86 | CRABP1 | 0.626692 | 4 | 0 | 4 |
| KRT86 | WRNIP1 | 0.610557 | 3 | 0 | 3 |
| KRT86 | ST8SIA3 | 0.59148 | 3 | 0 | 3 |
| KRT86 | MYBPH | 0.590327 | 6 | 0 | 4 |
| KRT86 | GDF9 | 0.583534 | 4 | 0 | 3 |
| KRT86 | CRHR2 | 0.582744 | 3 | 0 | 3 |
| KRT86 | RNASE3 | 0.581776 | 4 | 0 | 3 |
| KRT86 | GIP | 0.576803 | 4 | 0 | 3 |
| KRT86 | ASPHD1 | 0.572883 | 5 | 0 | 5 |
| KRT86 | APC2 | 0.570959 | 4 | 0 | 3 |
| KRT86 | KIR2DL2 | 0.565518 | 5 | 0 | 4 |
| KRT86 | NOC4L | 0.563984 | 3 | 0 | 3 |
| KRT86 | NYX | 0.563379 | 4 | 0 | 4 |
| KRT86 | SCGN | 0.56325 | 3 | 0 | 3 |
| KRT86 | OXTR | 0.560573 | 3 | 0 | 3 |
| KRT86 | SNAP25 | 0.558283 | 4 | 0 | 3 |
| KRT86 | TSPAN9 | 0.557629 | 4 | 0 | 3 |
For details and further investigation, click here
