| Full name: PAS domain containing serine/threonine kinase | Alias Symbol: PASKIN|KIAA0135|STK37 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 23178 | HGNC ID: HGNC:17270 | Ensembl Gene: ENSG00000115687 | OMIM ID: 607505 |
| Drug and gene relationship at DGIdb | |||
Expression of PASK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PASK | 23178 | 216945_x_at | -0.0095 | 0.9925 | |
| GSE20347 | PASK | 23178 | 213534_s_at | 0.0934 | 0.5885 | |
| GSE23400 | PASK | 23178 | 213534_s_at | -0.0560 | 0.2938 | |
| GSE26886 | PASK | 23178 | 206594_at | 0.0329 | 0.9288 | |
| GSE29001 | PASK | 23178 | 216945_x_at | 0.0976 | 0.6921 | |
| GSE38129 | PASK | 23178 | 213534_s_at | 0.1562 | 0.3726 | |
| GSE45670 | PASK | 23178 | 213534_s_at | 0.5860 | 0.0031 | |
| GSE53622 | PASK | 23178 | 90964 | 0.3563 | 0.0053 | |
| GSE53624 | PASK | 23178 | 90964 | 0.1018 | 0.2597 | |
| GSE63941 | PASK | 23178 | 216945_x_at | 0.8588 | 0.0172 | |
| GSE77861 | PASK | 23178 | 216945_x_at | 0.3145 | 0.0106 | |
| GSE97050 | PASK | 23178 | A_24_P299911 | 0.6784 | 0.1618 | |
| SRP007169 | PASK | 23178 | RNAseq | 0.9158 | 0.0992 | |
| SRP008496 | PASK | 23178 | RNAseq | 0.5838 | 0.1207 | |
| SRP064894 | PASK | 23178 | RNAseq | 0.2532 | 0.3913 | |
| SRP133303 | PASK | 23178 | RNAseq | 0.1483 | 0.5858 | |
| SRP159526 | PASK | 23178 | RNAseq | 0.7381 | 0.0735 | |
| SRP193095 | PASK | 23178 | RNAseq | 0.2936 | 0.0742 | |
| SRP219564 | PASK | 23178 | RNAseq | 0.0682 | 0.8824 | |
| TCGA | PASK | 23178 | RNAseq | 0.2392 | 0.0058 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PASK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PASK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PASK | 23178 | 1 | 12 | 17 | |
| GSE20123 | PASK | 23178 | 1 | 12 | 17 | |
| GSE43470 | PASK | 23178 | 1 | 9 | 33 | |
| GSE46452 | PASK | 23178 | 0 | 5 | 54 | |
| GSE47630 | PASK | 23178 | 4 | 5 | 31 | |
| GSE54993 | PASK | 23178 | 4 | 3 | 63 | |
| GSE54994 | PASK | 23178 | 8 | 9 | 36 | |
| GSE60625 | PASK | 23178 | 0 | 3 | 8 | |
| GSE74703 | PASK | 23178 | 1 | 7 | 28 | |
| GSE74704 | PASK | 23178 | 1 | 5 | 14 | |
| TCGA | PASK | 23178 | 12 | 28 | 56 |
Total number of gains: 33; Total number of losses: 98; Total Number of normals: 357.
Somatic mutations of PASK:
Generating mutation plots.
Highly correlated genes for PASK:
Showing top 20/221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PASK | ST6GALNAC2 | 0.700136 | 3 | 0 | 3 |
| PASK | WDR66 | 0.693887 | 3 | 0 | 3 |
| PASK | LACTB2 | 0.680021 | 3 | 0 | 3 |
| PASK | CDH3 | 0.674625 | 3 | 0 | 3 |
| PASK | PRIM1 | 0.670099 | 4 | 0 | 3 |
| PASK | UBE2T | 0.666972 | 5 | 0 | 4 |
| PASK | SNRPE | 0.664555 | 4 | 0 | 3 |
| PASK | PLK1 | 0.664193 | 4 | 0 | 3 |
| PASK | CDCA2 | 0.656444 | 4 | 0 | 3 |
| PASK | SLC25A13 | 0.655849 | 4 | 0 | 4 |
| PASK | PBK | 0.653984 | 5 | 0 | 5 |
| PASK | RAP1GAP2 | 0.647965 | 3 | 0 | 3 |
| PASK | GMNN | 0.647241 | 4 | 0 | 4 |
| PASK | PLCG2 | 0.637421 | 4 | 0 | 3 |
| PASK | CKS1B | 0.634097 | 4 | 0 | 3 |
| PASK | DSG2 | 0.632404 | 4 | 0 | 3 |
| PASK | KRT18 | 0.631565 | 3 | 0 | 3 |
| PASK | CCDC137 | 0.628925 | 3 | 0 | 3 |
| PASK | CDC45 | 0.625909 | 5 | 0 | 4 |
| PASK | CPNE2 | 0.624789 | 3 | 0 | 3 |
For details and further investigation, click here
