| Full name: cyclin O | Alias Symbol: UDG2|FLJ22422|UNG2 | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 10309 | HGNC ID: HGNC:18576 | Ensembl Gene: ENSG00000152669 | OMIM ID: 607752 |
| Drug and gene relationship at DGIdb | |||
Expression of CCNO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNO | 10309 | 210021_s_at | 0.6049 | 0.0749 | |
| GSE20347 | CCNO | 10309 | 210021_s_at | 0.1120 | 0.3340 | |
| GSE23400 | CCNO | 10309 | 210021_s_at | 0.0838 | 0.0173 | |
| GSE26886 | CCNO | 10309 | 210021_s_at | 0.6644 | 0.0001 | |
| GSE29001 | CCNO | 10309 | 210021_s_at | 0.1517 | 0.3758 | |
| GSE38129 | CCNO | 10309 | 210021_s_at | 0.5166 | 0.0144 | |
| GSE45670 | CCNO | 10309 | 210021_s_at | 0.9130 | 0.0003 | |
| GSE53622 | CCNO | 10309 | 19784 | 0.7178 | 0.0029 | |
| GSE53624 | CCNO | 10309 | 19784 | 0.8468 | 0.0000 | |
| GSE63941 | CCNO | 10309 | 210021_s_at | 1.4172 | 0.0219 | |
| GSE77861 | CCNO | 10309 | 210021_s_at | 0.2115 | 0.3332 | |
| SRP159526 | CCNO | 10309 | RNAseq | 1.4368 | 0.0224 | |
| SRP219564 | CCNO | 10309 | RNAseq | 1.7578 | 0.0713 | |
| TCGA | CCNO | 10309 | RNAseq | -0.2287 | 0.2333 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCNO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNO | 10309 | 1 | 13 | 16 | |
| GSE20123 | CCNO | 10309 | 1 | 13 | 16 | |
| GSE43470 | CCNO | 10309 | 1 | 12 | 30 | |
| GSE46452 | CCNO | 10309 | 1 | 27 | 31 | |
| GSE47630 | CCNO | 10309 | 2 | 16 | 22 | |
| GSE54993 | CCNO | 10309 | 8 | 1 | 61 | |
| GSE54994 | CCNO | 10309 | 3 | 20 | 30 | |
| GSE60625 | CCNO | 10309 | 0 | 0 | 11 | |
| GSE74703 | CCNO | 10309 | 1 | 9 | 26 | |
| GSE74704 | CCNO | 10309 | 1 | 6 | 13 | |
| TCGA | CCNO | 10309 | 8 | 45 | 43 |
Total number of gains: 27; Total number of losses: 162; Total Number of normals: 299.
Somatic mutations of CCNO:
Generating mutation plots.
Highly correlated genes for CCNO:
Showing top 20/450 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNO | CYB561A3 | 0.682001 | 4 | 0 | 4 |
| CCNO | CD276 | 0.681899 | 4 | 0 | 4 |
| CCNO | HIP1 | 0.675905 | 3 | 0 | 3 |
| CCNO | PRSS36 | 0.671826 | 3 | 0 | 3 |
| CCNO | TXNDC12 | 0.666375 | 4 | 0 | 4 |
| CCNO | TRAPPC1 | 0.661925 | 3 | 0 | 3 |
| CCNO | FBLIM1 | 0.649932 | 4 | 0 | 4 |
| CCNO | NOB1 | 0.647039 | 3 | 0 | 3 |
| CCNO | HOXC9 | 0.64549 | 4 | 0 | 4 |
| CCNO | NEURL1B | 0.644449 | 3 | 0 | 3 |
| CCNO | CERS2 | 0.641845 | 4 | 0 | 3 |
| CCNO | GLI3 | 0.639667 | 3 | 0 | 3 |
| CCNO | TRAF3 | 0.638331 | 4 | 0 | 3 |
| CCNO | PGP | 0.636607 | 4 | 0 | 3 |
| CCNO | KIF18A | 0.635971 | 3 | 0 | 3 |
| CCNO | TSEN54 | 0.634178 | 3 | 0 | 3 |
| CCNO | PIGT | 0.632312 | 3 | 0 | 3 |
| CCNO | MECP2 | 0.631781 | 3 | 0 | 3 |
| CCNO | LAMB3 | 0.629729 | 7 | 0 | 5 |
| CCNO | CLIP2 | 0.629111 | 5 | 0 | 5 |
For details and further investigation, click here
