| Full name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | Alias Symbol: XIP|MGC71071 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 10542 | HGNC ID: HGNC:17955 | Ensembl Gene: ENSG00000134248 | OMIM ID: 608521 |
Screen Evidence:
| |||
LAMTOR5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway | |
| hsa05161 | Hepatitis B |
Expression of LAMTOR5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAMTOR5 | 10542 | 202300_at | -0.1866 | 0.6916 | |
| GSE20347 | LAMTOR5 | 10542 | 202300_at | -0.2658 | 0.1112 | |
| GSE23400 | LAMTOR5 | 10542 | 202300_at | -0.0252 | 0.7336 | |
| GSE26886 | LAMTOR5 | 10542 | 202299_s_at | -0.5503 | 0.0058 | |
| GSE29001 | LAMTOR5 | 10542 | 202299_s_at | -0.3505 | 0.2729 | |
| GSE38129 | LAMTOR5 | 10542 | 202300_at | -0.0540 | 0.7129 | |
| GSE45670 | LAMTOR5 | 10542 | 202299_s_at | 0.0095 | 0.9563 | |
| GSE53622 | LAMTOR5 | 10542 | 127665 | -0.2411 | 0.0000 | |
| GSE53624 | LAMTOR5 | 10542 | 127665 | -0.0351 | 0.5448 | |
| GSE63941 | LAMTOR5 | 10542 | 202300_at | 0.0382 | 0.9378 | |
| GSE77861 | LAMTOR5 | 10542 | 202299_s_at | -0.2472 | 0.2891 | |
| SRP007169 | LAMTOR5 | 10542 | RNAseq | -0.6287 | 0.0645 | |
| SRP008496 | LAMTOR5 | 10542 | RNAseq | -0.7394 | 0.0003 | |
| SRP064894 | LAMTOR5 | 10542 | RNAseq | -0.0266 | 0.9034 | |
| SRP133303 | LAMTOR5 | 10542 | RNAseq | 0.2316 | 0.1227 | |
| SRP159526 | LAMTOR5 | 10542 | RNAseq | -0.3017 | 0.1852 | |
| SRP193095 | LAMTOR5 | 10542 | RNAseq | -0.3860 | 0.0065 | |
| SRP219564 | LAMTOR5 | 10542 | RNAseq | -0.1099 | 0.6655 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LAMTOR5 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LAMTOR5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LAMTOR5 | 10542 | 0 | 11 | 19 | |
| GSE20123 | LAMTOR5 | 10542 | 0 | 11 | 19 | |
| GSE43470 | LAMTOR5 | 10542 | 0 | 8 | 35 | |
| GSE46452 | LAMTOR5 | 10542 | 2 | 1 | 56 | |
| GSE47630 | LAMTOR5 | 10542 | 9 | 5 | 26 | |
| GSE54993 | LAMTOR5 | 10542 | 0 | 1 | 69 | |
| GSE54994 | LAMTOR5 | 10542 | 7 | 4 | 42 | |
| GSE60625 | LAMTOR5 | 10542 | 0 | 0 | 11 | |
| GSE74703 | LAMTOR5 | 10542 | 0 | 7 | 29 | |
| GSE74704 | LAMTOR5 | 10542 | 0 | 7 | 13 | |
| TCGA | LAMTOR5 | 10542 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 81; Total Number of normals: 380.
Somatic mutations of LAMTOR5:
Generating mutation plots.
Highly correlated genes for LAMTOR5:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAMTOR5 | SDHC | 0.681757 | 3 | 0 | 3 |
| LAMTOR5 | FEM1B | 0.680924 | 3 | 0 | 3 |
| LAMTOR5 | SAMD8 | 0.649227 | 3 | 0 | 3 |
| LAMTOR5 | ARL16 | 0.621161 | 3 | 0 | 3 |
| LAMTOR5 | RPS12 | 0.610523 | 6 | 0 | 4 |
| LAMTOR5 | MT1HL1 | 0.610154 | 3 | 0 | 3 |
| LAMTOR5 | EIF2S3 | 0.604763 | 4 | 0 | 4 |
| LAMTOR5 | CEPT1 | 0.604359 | 10 | 0 | 8 |
| LAMTOR5 | PRPF38B | 0.601913 | 6 | 0 | 4 |
| LAMTOR5 | SDF2 | 0.591214 | 3 | 0 | 3 |
| LAMTOR5 | WDR47 | 0.589947 | 6 | 0 | 3 |
| LAMTOR5 | LMO2 | 0.58948 | 4 | 0 | 3 |
| LAMTOR5 | STXBP3 | 0.586538 | 7 | 0 | 5 |
| LAMTOR5 | PRKAG1 | 0.584558 | 6 | 0 | 5 |
| LAMTOR5 | AHCYL1 | 0.583376 | 7 | 0 | 5 |
| LAMTOR5 | MIPEP | 0.582564 | 5 | 0 | 4 |
| LAMTOR5 | VPS29 | 0.580335 | 4 | 0 | 3 |
| LAMTOR5 | RABGGTB | 0.578765 | 6 | 0 | 4 |
| LAMTOR5 | PSMA5 | 0.577162 | 10 | 0 | 6 |
| LAMTOR5 | PDIK1L | 0.576818 | 4 | 0 | 3 |
For details and further investigation, click here
