| Full name: metallothionein 1H like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 645745 | HGNC ID: HGNC:31864 | Ensembl Gene: ENSG00000244020 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MT1HL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MT1HL1 | 645745 | 211456_x_at | 0.0341 | 0.9714 | |
| GSE20347 | MT1HL1 | 645745 | 211456_x_at | 0.0367 | 0.8816 | |
| GSE23400 | MT1HL1 | 645745 | 211456_x_at | -0.2088 | 0.0669 | |
| GSE26886 | MT1HL1 | 645745 | 211456_x_at | 0.1824 | 0.7224 | |
| GSE29001 | MT1HL1 | 645745 | 211456_x_at | -0.4365 | 0.1076 | |
| GSE38129 | MT1HL1 | 645745 | 211456_x_at | -0.0552 | 0.8249 | |
| GSE45670 | MT1HL1 | 645745 | 211456_x_at | -0.5186 | 0.0571 | |
| GSE53622 | MT1HL1 | 645745 | 162585 | -0.8265 | 0.0000 | |
| GSE53624 | MT1HL1 | 645745 | 162585 | -0.8832 | 0.0000 | |
| GSE63941 | MT1HL1 | 645745 | 211456_x_at | -1.7094 | 0.1466 | |
| GSE77861 | MT1HL1 | 645745 | 211456_x_at | -0.5406 | 0.2076 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MT1HL1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MT1HL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT1HL1 | 645745 | 10 | 1 | 19 | |
| GSE20123 | MT1HL1 | 645745 | 10 | 1 | 19 | |
| GSE43470 | MT1HL1 | 645745 | 8 | 1 | 34 | |
| GSE46452 | MT1HL1 | 645745 | 4 | 2 | 53 | |
| GSE47630 | MT1HL1 | 645745 | 15 | 0 | 25 | |
| GSE54993 | MT1HL1 | 645745 | 0 | 6 | 64 | |
| GSE54994 | MT1HL1 | 645745 | 16 | 0 | 37 | |
| GSE60625 | MT1HL1 | 645745 | 0 | 0 | 11 | |
| GSE74703 | MT1HL1 | 645745 | 8 | 1 | 27 | |
| GSE74704 | MT1HL1 | 645745 | 4 | 0 | 16 | |
| TCGA | MT1HL1 | 645745 | 43 | 4 | 49 |
Total number of gains: 118; Total number of losses: 16; Total Number of normals: 354.
Somatic mutations of MT1HL1:
Generating mutation plots.
Highly correlated genes for MT1HL1:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT1HL1 | MT1H | 0.953235 | 11 | 0 | 11 |
| MT1HL1 | MT1G | 0.929102 | 9 | 0 | 9 |
| MT1HL1 | MT1X | 0.8757 | 11 | 0 | 10 |
| MT1HL1 | MT1F | 0.861269 | 11 | 0 | 9 |
| MT1HL1 | MT2A | 0.834743 | 11 | 0 | 9 |
| MT1HL1 | MT1E | 0.722735 | 11 | 0 | 11 |
| MT1HL1 | RABGGTB | 0.683703 | 3 | 0 | 3 |
| MT1HL1 | FAM187B | 0.669196 | 3 | 0 | 3 |
| MT1HL1 | SOCS3 | 0.661217 | 3 | 0 | 3 |
| MT1HL1 | LEPROT | 0.63913 | 4 | 0 | 3 |
| MT1HL1 | KIFC3 | 0.633418 | 3 | 0 | 3 |
| MT1HL1 | LAMTOR5 | 0.610154 | 3 | 0 | 3 |
| MT1HL1 | CXCL3 | 0.58881 | 3 | 0 | 3 |
| MT1HL1 | FEZ2 | 0.584746 | 4 | 0 | 4 |
| MT1HL1 | SPATA3-AS1 | 0.581298 | 3 | 0 | 3 |
| MT1HL1 | VAMP3 | 0.57594 | 4 | 0 | 3 |
| MT1HL1 | MT1M | 0.56832 | 10 | 0 | 7 |
| MT1HL1 | BCAR3 | 0.565637 | 4 | 0 | 3 |
| MT1HL1 | ZBED2 | 0.56466 | 3 | 0 | 3 |
| MT1HL1 | SGMS2 | 0.564445 | 3 | 0 | 3 |
For details and further investigation, click here
