| Full name: leupaxin | Alias Symbol: LDPL | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 9404 | HGNC ID: HGNC:14061 | Ensembl Gene: ENSG00000110031 | OMIM ID: 605390 |
| Drug and gene relationship at DGIdb | |||
Expression of LPXN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPXN | 9404 | 216250_s_at | 0.6510 | 0.5842 | |
| GSE20347 | LPXN | 9404 | 216250_s_at | 0.0562 | 0.8279 | |
| GSE23400 | LPXN | 9404 | 216250_s_at | 0.1570 | 0.0630 | |
| GSE26886 | LPXN | 9404 | 216250_s_at | -0.7432 | 0.0700 | |
| GSE29001 | LPXN | 9404 | 216250_s_at | -0.0580 | 0.8051 | |
| GSE38129 | LPXN | 9404 | 216250_s_at | 0.0199 | 0.9432 | |
| GSE45670 | LPXN | 9404 | 216250_s_at | 0.1132 | 0.7922 | |
| GSE53622 | LPXN | 9404 | 9168 | 0.1528 | 0.0909 | |
| GSE53624 | LPXN | 9404 | 9168 | 0.0746 | 0.3913 | |
| GSE63941 | LPXN | 9404 | 216250_s_at | -1.3008 | 0.2302 | |
| GSE77861 | LPXN | 9404 | 242778_at | -0.0115 | 0.9322 | |
| GSE97050 | LPXN | 9404 | A_23_P87150 | 0.3329 | 0.3451 | |
| SRP007169 | LPXN | 9404 | RNAseq | 1.1402 | 0.1600 | |
| SRP008496 | LPXN | 9404 | RNAseq | 0.1355 | 0.7997 | |
| SRP064894 | LPXN | 9404 | RNAseq | 0.7012 | 0.0084 | |
| SRP133303 | LPXN | 9404 | RNAseq | 0.1109 | 0.6216 | |
| SRP159526 | LPXN | 9404 | RNAseq | -0.5388 | 0.4059 | |
| SRP193095 | LPXN | 9404 | RNAseq | 0.1183 | 0.5456 | |
| SRP219564 | LPXN | 9404 | RNAseq | 0.5499 | 0.0968 | |
| TCGA | LPXN | 9404 | RNAseq | 0.0905 | 0.4894 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LPXN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPXN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPXN | 9404 | 1 | 4 | 25 | |
| GSE20123 | LPXN | 9404 | 1 | 4 | 25 | |
| GSE43470 | LPXN | 9404 | 1 | 5 | 37 | |
| GSE46452 | LPXN | 9404 | 10 | 4 | 45 | |
| GSE47630 | LPXN | 9404 | 3 | 8 | 29 | |
| GSE54993 | LPXN | 9404 | 3 | 0 | 67 | |
| GSE54994 | LPXN | 9404 | 5 | 6 | 42 | |
| GSE60625 | LPXN | 9404 | 0 | 3 | 8 | |
| GSE74703 | LPXN | 9404 | 1 | 3 | 32 | |
| GSE74704 | LPXN | 9404 | 1 | 4 | 15 | |
| TCGA | LPXN | 9404 | 14 | 10 | 72 |
Total number of gains: 40; Total number of losses: 51; Total Number of normals: 397.
Somatic mutations of LPXN:
Generating mutation plots.
Highly correlated genes for LPXN:
Showing top 20/276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPXN | FERMT3 | 0.723659 | 3 | 0 | 3 |
| LPXN | CD53 | 0.72219 | 9 | 0 | 8 |
| LPXN | LAPTM5 | 0.71395 | 10 | 0 | 9 |
| LPXN | GRAPL | 0.696805 | 3 | 0 | 3 |
| LPXN | EVI2B | 0.695641 | 12 | 0 | 11 |
| LPXN | BCL2L11 | 0.687762 | 3 | 0 | 3 |
| LPXN | SLA | 0.682562 | 11 | 0 | 11 |
| LPXN | TNFRSF1B | 0.661163 | 11 | 0 | 10 |
| LPXN | IL2RG | 0.658433 | 9 | 0 | 8 |
| LPXN | BTK | 0.654983 | 6 | 0 | 4 |
| LPXN | ARRB2 | 0.651344 | 4 | 0 | 3 |
| LPXN | SELL | 0.651134 | 9 | 0 | 6 |
| LPXN | IL10RA | 0.650613 | 10 | 0 | 8 |
| LPXN | NCKAP1L | 0.646183 | 11 | 0 | 10 |
| LPXN | SMAP2 | 0.644388 | 7 | 0 | 7 |
| LPXN | GZMK | 0.641905 | 7 | 0 | 5 |
| LPXN | ITGB2 | 0.640977 | 12 | 0 | 9 |
| LPXN | RHOH | 0.639948 | 9 | 0 | 6 |
| LPXN | CD84 | 0.638453 | 10 | 0 | 9 |
| LPXN | DOCK10 | 0.633537 | 7 | 0 | 6 |
For details and further investigation, click here
